Navigation Links
What role do cytokines play in autoimmune diseases?
Date:10/27/2011

New Rochelle, NY, October 24, 2011Cytokines, a varied group of signaling chemicals in the body, have been described as the software that runs the immune system, but when that software malfunctions, dysregulation of the immune system can result in debilitating autoimmune diseases such as lupus, arthritis, and diabetes. Leading experts in the field of cytokine research present their most up-to-date findings and unique perspectives on the role of cytokines in autoimmune diseases in a special issue of Journal of Interferon & Cytokine Research, a peer-reviewed publication of Mary Ann Liebert, Inc. (www.liebertpub.com). The issue is available free online for a limited time at www.liebertpub.com/jir

Dhan Kalvakolanu, PhD, University of Maryland School of Medicine, Journal Co-Editors-in-Chief Ganes C. Sen, PhD, and Thomas A. Hamilton, PhD, Cleveland Clinic Foundation, together with Guest Editors Kamal Moudgil, MD, PhD, University of Maryland School of Medicine, and Divaker Choubey, PhD, University of Cincinnati have compiled a wealth of in-depth review articles, original research, and insightful perspectives from expert researchers on the evolving understanding of how cytokines can both contribute to the initiation of autoimmune diseases and control the inflammation associated with the acute phase of these diseases. This special issue of the Journal is the first in a two-volume collection of articles.

In his introductory Editorial, Dr. Kalvakolanu identifies cytokines as the first step in the onset of immune responses in which the body attacks its own cells and tissues, leading to the development of autoimmune diseases. Drs. Moudgil and Choubey present an overview of the role cytokines play in the induction, regulation, and treatment of autoimmunity. An original research article, "Critical Cytokine Pathways to Cardiac Inflammation," by Noel Rose, PhD, The Johns Hopkins Schools of Medicine and Public Health (Baltimore, MD), describes a mouse model of autoimmune myocarditisinflammation of the heart musclesthat is triggered by infection with Coxsackievirus B3. The model allows researchers to study the cytokine pathways involved in this disease, with the goal of identifying chemical markers that could be used to predict patients more likely to experience an autoimmune reaction after infection.


'/>"/>

Contact: Tracy Kasten
tkasten@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related biology news :

1. Xencor Initiates Phase 1 Study of XmAb®5871 Therapeutic Antibody for the Treatment of Autoimmune Diseases
2. Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases
3. Scientists discover a master key to unlock new treatments for autoimmune disorders
4. B-cell discovery suggests why women suffer more autoimmune disease
5. A promising new approach to autoimmune diseases
6. New clue to lupus: Failed autoimmune suppression mechanism
7. JAX publishes online tool for exploring autoimmune disease gene networks
8. Vitamin D may exacerbate autoimmune disease
9. Unexpected finding opens up new way to stop autoimmune diseases and transplant rejection
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
What role do cytokines play in autoimmune diseases?
(Date:4/3/2017)... 2017  Data captured by IsoCode, IsoPlexis ... a statistically significant association between the potency ... and objective response of cancer patients post-treatment. ... whether cancer patients will respond to CAR-T ... as to improve both pre-infusion potency testing and ...
(Date:3/30/2017)... 2017 The research team of The Hong ... fingerprint identification by adopting ground breaking 3D fingerprint minutiae recovery and ... speed and accuracy for use in identification, crime investigation, immigration control, ... ... A research team led ...
(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... Vortex Biosciences , provider of circulating tumor ... circulating tumor cells using Vortex microfluidic technology ” in Nature Precision Oncology on May ... Dino Di Carlo and Dr. Matthew Rettig at the University of California, Los Angeles. ...
(Date:5/23/2017)... , ... May 23, 2017 , ... Bacterial biofilms, surface ... molecules, can cause diverse pathologies ranging from food poisoning and catheter infections to gum ... is in the tens of billions of dollars per year, there is currently a ...
(Date:5/22/2017)... ... 22, 2017 , ... Stratevi, a boutique firm that partners with healthcare companies ... opened an office in downtown Boston at 745 Atlantic Ave. , “We are ... generate evidence on the value they provide, not just to patients, but also payers. ...
(Date:5/21/2017)... ANGELES, CA (PRWEB) , ... May 19, 2017 ... ... the annual meeting and educational conference of the American Association of Bioanalysts (AAB) ... the Galleria Hotel in Houston. The conference reinforces AAB’s commitment to excellence in ...
Breaking Biology Technology: