Navigation Links
What role do cytokines play in autoimmune diseases?
Date:10/27/2011

New Rochelle, NY, October 24, 2011Cytokines, a varied group of signaling chemicals in the body, have been described as the software that runs the immune system, but when that software malfunctions, dysregulation of the immune system can result in debilitating autoimmune diseases such as lupus, arthritis, and diabetes. Leading experts in the field of cytokine research present their most up-to-date findings and unique perspectives on the role of cytokines in autoimmune diseases in a special issue of Journal of Interferon & Cytokine Research, a peer-reviewed publication of Mary Ann Liebert, Inc. (www.liebertpub.com). The issue is available free online for a limited time at www.liebertpub.com/jir

Dhan Kalvakolanu, PhD, University of Maryland School of Medicine, Journal Co-Editors-in-Chief Ganes C. Sen, PhD, and Thomas A. Hamilton, PhD, Cleveland Clinic Foundation, together with Guest Editors Kamal Moudgil, MD, PhD, University of Maryland School of Medicine, and Divaker Choubey, PhD, University of Cincinnati have compiled a wealth of in-depth review articles, original research, and insightful perspectives from expert researchers on the evolving understanding of how cytokines can both contribute to the initiation of autoimmune diseases and control the inflammation associated with the acute phase of these diseases. This special issue of the Journal is the first in a two-volume collection of articles.

In his introductory Editorial, Dr. Kalvakolanu identifies cytokines as the first step in the onset of immune responses in which the body attacks its own cells and tissues, leading to the development of autoimmune diseases. Drs. Moudgil and Choubey present an overview of the role cytokines play in the induction, regulation, and treatment of autoimmunity. An original research article, "Critical Cytokine Pathways to Cardiac Inflammation," by Noel Rose, PhD, The Johns Hopkins Schools of Medicine and Public Health (Baltimore, MD), describes a mouse model of autoimmune myocarditisinflammation of the heart musclesthat is triggered by infection with Coxsackievirus B3. The model allows researchers to study the cytokine pathways involved in this disease, with the goal of identifying chemical markers that could be used to predict patients more likely to experience an autoimmune reaction after infection.


'/>"/>

Contact: Tracy Kasten
tkasten@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related biology news :

1. Xencor Initiates Phase 1 Study of XmAb®5871 Therapeutic Antibody for the Treatment of Autoimmune Diseases
2. Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases
3. Scientists discover a master key to unlock new treatments for autoimmune disorders
4. B-cell discovery suggests why women suffer more autoimmune disease
5. A promising new approach to autoimmune diseases
6. New clue to lupus: Failed autoimmune suppression mechanism
7. JAX publishes online tool for exploring autoimmune disease gene networks
8. Vitamin D may exacerbate autoimmune disease
9. Unexpected finding opens up new way to stop autoimmune diseases and transplant rejection
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
What role do cytokines play in autoimmune diseases?
(Date:6/7/2016)... , June 7, 2016  Syngrafii Inc. and ... business relationship that includes integrating Syngrafii,s patented LongPen™ ... project. This collaboration will result in greater convenience ... credit union, while maintaining existing document workflow and ... ...
(Date:6/2/2016)... -- The Department of Transport Management (DOTM) of ... US Dollar project, for the , Supply and ... and IT Infrastructure , to Decatur ... of Identity Management Solutions. Numerous renowned international vendors participated in ... was selected for the most compliant and innovative solution. ...
(Date:6/2/2016)... Perimeter Surveillance & Detection Systems, Biometrics & ... & Other Service  The latest report from ... of the global Border Security market . Visiongain ... billion in 2016. Now: In November 2015 ... and hardware technologies for advanced video surveillance. ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016  Liquid Biotech ... funding of a Sponsored Research Agreement with The ... cells (CTCs) from cancer patients.  The funding will ... levels correlate with clinical outcomes in cancer patients ... will then be employed to support the design ...
(Date:6/24/2016)... ... 2016 , ... While the majority of commercial spectrophotometers and fluorometers use the ... models are higher end machines that use the more unconventional z-dimension of 20mm. ... the bottom of the cuvette holder. , FireflySci has developed several Agilent flow ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
Breaking Biology Technology: