Navigation Links
What is the brain telling us about the diagnoses of schizophrenia and bipolar disorder?
Date:9/5/2013

differ primarily by degree or are there clear categorical differences? To answer this question, researchers from a large collaborative project called BSNIP looked at a large sample of patients diagnosed with schizophrenia or bipolar disorder, their healthy relatives, and healthy people without a family history of psychiatric disorder.

They used a specialized analysis technique to evaluate the data from their multi-site study, which revealed abnormalities within seven different brain networks. Generally speaking, they found that schizophrenia and bipolar disorder showed similar disturbances in cortical circuit function. When differences emerged between these two disorders, it was usually because schizophrenia appeared to be a more severe disease. In other words, individuals with schizophrenia had abnormalities that were larger or affected more brain regions. Their healthy relatives showed subtle alterations that fell between the healthy comparison group and the patient groups.

The authors highlight the possibility that there is a continuous spectrum of circuit dysfunction, spanning from individuals without any familial association with schizophrenia or bipolar to patients carrying these diagnoses. "These findings might serve as useful biological markers of psychotic illnesses in general," said Khadka.

Krystal agreed, adding, "It is evident that neither our genomes nor our brains have read DSM-V in that there are links across disorders that we had not previously imagined. These links suggest that new ways of organizing patients will emerge once we understand both the genetics and neural circuitry of psychiatric disorders sufficiently."


'/>"/>

Contact: Jordi van de Weerd
j.weerd@elsevier.com
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Discovery helps to unlock brains speech-learning mechanism
2. Learning a new language alters brain development
3. Human brains are hardwired for empathy, friendship, study shows
4. Playing video games can boost brain power
5. How brain microcircuits integrate information from different senses
6. Making the brain take notice of faces in autism
7. Protein involved in nerve-cell migration implicated in spread of brain cancer
8. Material in dissolvable sutures could treat brain infections, reducing hospital stays
9. Practice makes the brains motor cortex more efficient, Pitt researchers say
10. MIT researchers reveal how the brain keeps eyes on the prize
11. Study reveals potential role of love hormone oxytocin in brain function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... has different effects on different species of fish, ... of Bristol and Exeter which tested fish anti-predator ... a flying seagull predator model when exposed to ... European minnows. , Lead author Dr Irene ... "Noise levels in many aquatic environments have increased ...
(Date:7/24/2014)... 2014 Some sticky research out of York University ... certain species of toxic grass fungus: moose saliva (yes ... Biology Letters , "Ungulate saliva inhibits a grassendophyte mutualism" ... red fescue grass (which hosts a fungus called epichlo ... fungus growth and less toxicity. , "Plants have evolved ...
(Date:7/24/2014)... Bhavani Iyer, O.D., a low vision specialist at The ... Medical School, has been awarded a grant to help ... with eyeglasses, medication or surgery. , Even with corrective ... at best. However, there are a variety of low ... to help offset their vision loss. , Iyer is ...
Breaking Biology News(10 mins):Moose drool inhibits growth of toxic fungus: York U research 2UTHealth Dr. Bhavani Iyer awarded low vision grant 2
... of native North Americans offers new insights into the migration ... home in northwest North America to the southwestern United States. ... to have occurred about 500 years ago. The ... detailed this month in the American Journal of Physical ...
... literature review conducted by a team of researchers from ... and the Connecticut Center for Eliminating Health Disparities among ... and health outcomes among Latinos living in the United ... the Journal of Nutrition Education and Behavior, ...
... spotting the cuckoo in the nest. But if you don,t, ... hosts distinguish impostor eggs from their own has long puzzled ... through our own eyes. It was only when people started ... how hosts recognise a cuckoo egg in the nest. Marcel ...
Cached Biology News:Y chromosome study sheds light on Athapaskan migration to southwest US 2Y chromosome study sheds light on Athapaskan migration to southwest US 3Peers important for nutrition education among Latinos 2How birds spot the cuckoo in the nest 2
(Date:7/25/2014)... Pa. , July 25, 2014 /PRNewswire-iReach/ -- ... and consulting for global corporations operating in highly ... host its first annual Global User Group Conference, ... historic Philadelphia, Pennsylvania at ... - http://photos.prnewswire.com/prnh/20140724/130263 This ...
(Date:7/24/2014)... New York, NY - July 24, 2014 -- Keryx ... results from the long-term, randomized, active control Phase 3 ... ferric iron-based phosphate binder, for the treatment of hyperphosphatemia ... The PERFECTED study (PhosphatE binding and iRon delivery with ... the Journal of the American Society of Nephrology ...
(Date:7/24/2014)... Calif. , July 24, 2014  Now available ... to home. Rehealth Regenerative Therapies , located in ... and other physically active people a new health option: ... Regardless of age, countless patients suffer from joint ... activities, such as muscle tears, torn rotator cuff, tennis ...
(Date:7/24/2014)... Security forces worldwide rely on sophisticated equipment, trained ... other public areas against terrorist attacks. A revolutionary ... about to make their job much easier. , ... Patolsky of Tel Aviv University ,s School of ... developed by the Herzliya company Tracense, picks up ...
Breaking Biology Technology:Xybion Announces It Will Host International User Conference in Philadelphia 2Xybion Announces It Will Host International User Conference in Philadelphia 3Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 2Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 3Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 4Stem Cells In Sports Injuries, Joints And Muscular Pain 2Stem Cells In Sports Injuries, Joints And Muscular Pain 3Nano-sized chip 'sniffs out' explosives far better than trained dogs 2
... February 26 Arpida Ltd.,(SWX: ARPN) today reported that ... intravenous iclaprim in its first indication,complicated Skin and Skin ... weeks., Arpida has agreed with the U.S. Food ... rolling process. Using a ,rolling NDA, allows modules,within the ...
... using Star-P, WALTHAM, Mass., Feb. 26 ... Research Lab (NUCAR) and the National,Science Foundation,s ... (CenSSIS) are teaming with Massachusetts General Hospital ... technology that improves breast,cancer screening accuracy. The ...
... Talent Management Vendor,s Model ... Market, OTTAWA, Feb. 26 /PRNewswire/ - Halogen Software ... management software,today announced that FactPoint Group has profiled Halogen ... market. The Silicon Valley based research and,consulting firm selected ...
Cached Biology Technology:Arpida Provides Update on Progress of New Drug Application for Intravenous Iclaprim 2Arpida Provides Update on Progress of New Drug Application for Intravenous Iclaprim 3Northeastern University and Mass General Hospital Increase the Accuracy, While Reducing the Diagnosis Time, for Breast Cancer Detection 2Northeastern University and Mass General Hospital Increase the Accuracy, While Reducing the Diagnosis Time, for Breast Cancer Detection 3FactPoint Group Recognizes Halogen for "On-Choice" Deployment Model 2
Screening assay to detect the Listeria monocytogenes in food samples by,DNA amplification and molecular hybridization on a microtiter plate....
... CopyControl™ vector can be induced prior to ... provide the stability of single-copy BACs with ... other cloning vectors. The kits provide the ... insert size screening system) necessary to create ...
... PCR Enhancer (with betaine) substantially improves ... and specificity for amplification of many ... in PCR eliminates the base-pair composition ... thermal stability, suppresses pauses of DNA ...
... Systems provide rapid, precise localization of ... frozen or paraffin-embedded tissue, cytospins and ... facilitate double or triple labeleing experiments, ... with primary antibodies of different animal ...
Biology Products: