Navigation Links
What happens when we sleep
Date:1/28/2009

This release is available in French.

Lack of sleep is a common complaint but for many, falling asleep involuntarily during the day poses a very real and dangerous problem. A new study from the Montreal Neurological Institute (MNI) at McGill University demonstrates interestingly, that sleep-wake states are regulated by two different types of nerve cells (neurons), melanin-concentrating hormone (MCH) neurons and orexin (Orx) neurons, which occupy the same region of the brain but perform opposite functions. The MNI study is the first to discover that MCH neurons are activated during sleep and could thus be important in regulating the sleep state. The study, published in this week's issue of the journal Proceedings of the National Academy of Sciences (PNAS), provides deeper understanding of the sleep-wake cycle and vital insight into the basis of sleep disorders such as narcolepsy and possibly also other diseases such as depression and Parkinson's.

Sleep is regulated by processes in the brain in response to how long we are awake in addition to the light/dark cycle controlled by the circadian rhythm. With Drs. Oum Hassani and Maan Gee Lee, Dr. Barbara Jones at the MNI were studying a structure in the brain called the lateral hypothalamus (LH) known to be critical for maintaining wakefulness. MCH neurons, co-distributed with Orx neurons, constitute less than 10% of the LH. Previous studies have shown that Orx neurons are essential for maintenance of the awake state. These neurons are active in the waking state and turn off during sleep and in their absence, animals and humans experience narcolepsy with cataplexy or sudden loss of mucle tone. However, the role of MCH neurons was until now, unclear. Evidence from earlier knockout studies suggested that MCH neurons might play a different role than Orx neurons in regulating activity and slee
'/>"/>

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Dung happens and helps scientists
2. Mice roar message: genetic change happens fast
3. Dog owners more likely to share germs with pets by not washing hands than by sleeping with dog
4. Is there a relationship between sleep-wake rhythm and diabetes?
5. When it comes to sleep research, fruit flies and people make unlikely bedfellows
6. Study helps explain connection between sleep apnea, stroke and death
7. Practice as well as sleep may help birds learn new songs
8. Emotion and scent create lasting memories -- even in a sleeping brain
9. What a sleep study can reveal about fibromyalgia
10. Brain tweak lets sleep-deprived flies stay sharp
11. Sleep restriction results in increased consumption of energy from snacks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... According to a new market ... RFID, Access Control, Intrusion Detection, Parking Management, Under Vehicle ... Service Geography - Global Forecasts to 2020", published by ... be around $25 Billion in 2014 and is expected ... CAGR of 8.69%. Browse 116 market data ...
(Date:11/21/2014)... NEW YORK , Nov. 19, 2014  Earlier ... Board at New York College, and one of the ... for biosensor signals that are transmitted from Smartphones to ... there were Smartphones and has one of the earliest ... are discussing its usage in the military, child care, ...
(Date:11/21/2014)... MOUNTAIN VIEW, Calif. , Nov. 20, 2014 /PRNewswire/ ... for higher driver efficiency are piloting the North American ... the number of accidents growing, gesture recognition systems that ... will make a mark in the industry. ... of the Automotive Gesture Recognition Market in ...
Breaking Biology News(10 mins):Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 2Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 4
... suggests that a class of material known as metallacarborane could ... United States Department of Energy (DOE) Hydrogen Program for 2015. ... into play as a fuel of the future for cars, ... by Rice theoretical physicist Boris Yakobson and his colleagues, which ...
... has awarded 23 grants for structural biology research totaling ... will focus on determining the shapes and functions of ... awards are part of the Protein Structure Initiative (PSI), ... goal of developing highly efficient, or high-throughput, methods for ...
... report in the October 2010 print issue of the ... light on how our immune systems detect invading organisms to ... this research should ultimately help lead to the development of ... prevent runaway immune reactions that can have devastating consequences for ...
Cached Biology News:Hydrogen fuel for thought 2NIH grants will advance studies of the form and function of proteins 2NIH grants will advance studies of the form and function of proteins 3Scientists reveal important clues to how bacteria and viruses are identified as enemies 2
(Date:11/26/2014)... 2014 On January, 14, 2015, ... Washington D.C. science community to the UMBC campus for ... by the Protein Society, will take place from 9 ... 312. Through discussion, presentations and workshops, the free ... proteins, their role in the industry and the future ...
(Date:11/26/2014)... Whitehouse Laboratories is pleased to ... County (New Jersey) Chamber of Commerce as a ... organization in the North Jersey area, offers Whitehouse ... key clients in the pharmaceutical and biotechnology areas ... Membership enables Whitehouse Laboratories a higher level of ...
(Date:11/26/2014)... 2014 Continuing its award-winning streak, Nerium ... prestigious MarCom Awards for outstanding creative achievement by its ... MarCom Award, the organization’s top honor, in the Branding ... held in April of this year. The event showcased ... Additionally, Nerium was awarded a Gold MarCom Award in ...
(Date:11/26/2014)... West Chester, OH (PRWEB) November 25, 2014 ... International Holdings, has joined the Graphel Carbon Products team ... experience in sales, marketing, and customer service for the ... to add Miles to our team,” stated Dave Trinkley, ... Products. “His wide range of experience in the ...
Breaking Biology Technology:Whitehouse Laboratories Joins Morris County Chamber of Commerce 2Whitehouse Laboratories Joins Morris County Chamber of Commerce 3Nerium International™ Wins One Platinum, Two Gold MarCom Awards 2Miles Holder Joins Graphel Corporation as Sales/Marketing Manager 2
... an advance promising to dramatically reduce their dose of ... University School of Medicine in St. Louis have taken ... focused a powerful drug directly on tumors in rabbits ... 1,000 times lower than used previously for this purpose ...
... reduction, NEW YORK, April 4, 2008 ... it is implementing a,strategic restructuring plan to reduce ... The plan, which was prompted by the negative ... trial of Sulonex(TM),(sulodexide) for the treatment of diabetic ...
... April 4, 2008 Memory,Pharmaceuticals Corp. (Nasdaq: ... 2008,it received notice from The Nasdaq Stock Market ... with the minimum $10.0 million stockholders, equity,requirement for ... Rule 4450(a)(3). As reported in the Company,s Annual ...
Cached Biology Technology:Nanosized technology has supersized effect on tumors 2Nanosized technology has supersized effect on tumors 3Keryx Biopharmaceuticals Announces Implementation of Strategic Restructuring Plan 2Keryx Biopharmaceuticals Announces Implementation of Strategic Restructuring Plan 3Keryx Biopharmaceuticals Announces Implementation of Strategic Restructuring Plan 4Memory Pharmaceuticals Receives Nasdaq Notification 2Memory Pharmaceuticals Receives Nasdaq Notification 3
... Clone/PAD: ZMD.366. Immunogen: ... internal region of human SENP1. ... human ~73 kDa SENP1. ... or DYKDDDDK)-HA-tagged-SENP1 transfected Hep2 cell ...
...
...
Request Info...
Biology Products: