Navigation Links
Western researchers receive $600,000 to study Prion diseases and Alzheimer's
Date:7/20/2011

The University of Western Ontario is one of nine universities which will share 2.9 million dollars in research grants announced by PrioNet Canada to study Prion diseases and neurodegenerative disorders including Alzheimer's. Prion diseases are fatal, infectious and transmissible neurodegenerative diseases affecting both humans and animals including mad cow disease or bovine spongiform encephalopathy (BSE), Creutzfeldt-Jakob disease (CJD) in humans, and chronic wasting disease (CWD) in deer and elk.

The goal of the funding which supports 11 projects is two-fold, explains Dr. Neil Cashman, Scientific Director of PrioNet Canada, one of Canada's Network of Centres of Excellence. "By working with our partners, we aim to continue to protect Canada against classical Prion diseases like chronic wasting disease and mad cow disease, and we're also providing benefit to Canadians through the development of innovative therapeutics to treat common neurodegenerative diseases like Alzheimer's, Parkinson's and ALS."

The research team from Western's Schulich School of Medicine & Dentistry includes: Marco Prado, Jane Rylett, Stephen Ferguson, Vania Prado, John MacDonald, James Choy, Rob Bartha, Michael Strong and Ravi Menon. Other collaborators are Neil Cashman from University of British Columbia, and Vilma Martins and Glaucia Hajj at the A. C. Camargo Hospital in Brazil. The team will receive $600,000 to investigate whether the prion protein could be a therapeutic target in Alzheimer disease.

"Both Alzheimer's and Prion are neurodegenerative diseases, and in both neurons die," explains Marco Prado, a scientist at the Robarts Research Institute. "We are starting to realize that prion protein which plays a major role in Prion diseases might also play a role in Alzheimer's by interacting with amyloid beta, one of the toxins in Alzheimer's. This interaction could affect the way neurons function, or may even cause their death. The support from PrioNet Canada will allow us to test if this hypothesis is correct and hopefully to find novel therapeutics for both diseases."

Both diseases take a heavy toll on lives and the country's economy. In 2010, the cost of dementia in Canada was estimated at $22 billion a year. In 2003, markets were closed to Canadian beef after a case of BSE was found in Alberta, causing an economic loss estimated at more than $6 billion.


'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Related biology news :

1. UT Southwestern research reveals that significantly more genetic mutations lead to colon cancer
2. UT Southwestern researchers find protein breakdown contributes to pelvic organ prolapse
3. UT Southwestern researchers find protein that might be key to cutting cancer cells blood supply
4. UT Southwestern research reveals how cancer-driving enzyme works
5. Case Western Reserve and NeoProteomics announce exclusive option
6. Scientists study control of invasive tree in western US
7. Signaling path in brain may prevent that Im full message, UT Southwestern scientists discover
8. Team of scientists predicts continued death of forests in southwestern US due to climate change
9. NIH awards $6.4 million to Case Western Reserve School of Medicine researchers
10. UT Southwestern researchers uncover culprits in life-threatening clotting disorder
11. Invading weed threatens devastation to western rangelands
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2017)... 2017  Socionext Inc., a global expert in SoC-based imaging and ... the M820, which features the company,s hybrid codec technology. A demonstration ... Probe, Inc., will be showcased during the upcoming Medtec Japan at ... the Las Vegas Convention Center April 24-27. ... Click here for an ...
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
(Date:4/5/2017)... YORK , April 5, 2017 Today ... is announcing that the server component of the HYPR ... known for providing the end-to-end security architecture that empowers ... HYPR has already secured over 15 million ... makers including manufacturers of connected home product suites and ...
Breaking Biology News(10 mins):
(Date:5/18/2017)... ... May 17, 2017 , ... USDM Life Sciences ... the life sciences and healthcare industries, is honored that Jay Crowley ... conference in Brussels, Belgium. , Crowley played a crucial role in the development ...
(Date:5/16/2017)... Basel, Switzerland (PRWEB) , ... May 16, 2017 ... ... for R&D, today announced its global Genedata Screener User Group Meetings, ... Genedata Screener users the opportunity to share best practices in screening data analysis ...
(Date:5/16/2017)... ... (PRWEB) May 16, 2017 , ... ... of Orthopaedic Surgeons (CAOS), long-standing development partners Invibio Biomaterial Solutions, UK, and ... surgery workshop to help expand knowledge of the implantation of Double Medical’s ...
(Date:5/15/2017)... ... May 15, 2017 , ... Continuing to ... skincare brand has today launched its first-ever cross-medium campaign, #StandFirm, with high-visibility social ... digital and social media channels, emphasizing Algenist’s stance on individuality and disruption: ...
Breaking Biology Technology: