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Weill Cornell science briefs June/July 2008

"It takes far too long for the vesicles to move from all the way in the cell body to another cell. These vesicles are made in New York and slowly transported to the cell's terminal end, but some are made right in Boston for immediate use." Dr. Ryan hopes that by understanding the mechanics of the cellular trafficking machine, he and other scientists will ultimately be able to identify and repair numerous neurologic malfunctions.

News About Inflammatory Bowel Disease, Crohn's Disease:

Stem Cells Heal Chronic Inflammation in the Gut
May Help Restore Immune System to Normal Function for Crohn's Disease

Stem cells are being studied at NewYork-Presbyterian/Weill Cornell to heal the gut in subjects suffering from Crohn's disease. Physician-scientists believe that these cells might help to restore the ability of the immune system to control inflammation by secreting anti-inflammatory proteins into the digestive tract, allowing for regeneration of tissue and prevention of scar tissue. It is believed that Crohn's disease results from a malfunctioned immune response, leading to uncontrolled inflammation in the tissues of the intestine. Diarrhea, painful cramping, blood in stool, ulcers and other wounds in the digestive tract are all possible symptoms of the disease.

Patients who have previously failed to benefit from medications for Crohn's disease are enrolled in the trial to test the safety and efficacy of the procedure. Each subject receives four infusions -- intravenous transplantation -- of mesenchymal stem cells, which are universally compatible in all people, like type-O blood.

For more information: Please contact Cynthia Cabral at 212-746-5118.

Drug for Treatment of Inflammatory Bowel Disease
New Formula Allows for Greater Absorption, Fewer Doses

Physician-scientists from NewYork-Presbyterian/Weill Cornell, involved in clinical trials for a new drug for those

Contact: Andrew Klein
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College

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Related biology news :

1. Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell team reports
2. 2 federal public health grants awarded to Weill Cornell Medical College
3. $13 million federal grant for research into vascular disease awarded to Weill Cornell
4. Weill Cornell team discovers how brains own tPA helps regulate blood flow to neurons
5. Cornell will host the Northeast Biofuel Summit, Nov. 11-13
6. First symposium of UN University-Cornell Africa Series to be held at UN
7. Wiggle room: Cornell researcher borrows idea from sperm to provide energy for nanoscale robots
8. Cornell researcher seeks clues to how tuberculosis infects cells
9. Cornell researchers prove how plants transport sugars
10. Cornell patents a pink lily look-alike that blooms all summer long
11. The 12th International Behavioral Ecology Congress held at Cornell University, Aug. 10-14
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