Navigation Links
Weatherstone Fellows publish research as Autism Speaks announces 2011 Weatherstone Fellows
Date:6/30/2011

NEW YORK, N.Y. (June 30, 2011) Autism Speaks Weatherstone Pre-Doctoral Fellows M. Ali Bangash, a 2009 fellow, and Mehreen Kouser, a 2010 fellow, recently published new findings in the journal Cell that shed light on the biology of autism. Their research is based on a mouse model that mimics a human mutation of a gene that is known to be associated with autism spectrum disorder (ASD), known as SHANK3. Mutations of this gene have recently been implicated in a subset of individuals with autism "Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism" details a new SHANK3 mutant mouse and demonstrates how this autism-associated gene affects brain functioning. Examining the genetic causes of autism, Bangash worked with mentor Paul Worley, M.D. of Johns Hopkins University, and Kouser worked with mentor Craig Powell at the University of Texas Southwestern Medical Center at Dallas to refine a mouse model to study the gene SHANK3 and investigate its implications for autism. Their work specifically shows that the gene is involved in how neurons communicate at synapses. When this gene mutation was recreated in a mouse, the animals had significant changes in a neurotransmitter, glutamate, which regulates communication between neurons in the brain and results in behavioral deficits consistent with symptoms of autism.

"This is significant published research from our Weatherstone Fellows portfolio. We are pleased to see the fruits of their efforts so soon, and the exceptional caliber of this work is representative of the excellence in this group of scientists who are pursuing the next generation of autism research," said Geraldine Dawson, Ph.D., chief science officer for Autism Speaks.

Cheryl Weatherstone Vance recently told a gathering of Weatherstone fellows, "My father, along with the Stavros Niarchos Foundation, wanted the brightest minds in the country to find answers to the mysteries of autism. You are on an in
'/>"/>

Contact: Jane E. Rubinstein
jrubinstein@rubenstein.com
212-843-8287
Autism Speaks
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Autism Speaks awards second class of Dennis Weatherstone pre-doctoral fellowships
2. 2008 SNM Wagner-Torizuka Fellowships announced
3. Soil Science Society of America presents 2008 fellows
4. Carnegies Field and Koshland Elected AAAS Fellows
5. Eight ASU faculty elected as AAAS Fellows
6. When it comes to sleep research, fruit flies and people make unlikely bedfellows
7. Damon Runyon Cancer Research Foundation awards prestigious fellowships to 13 top young investigators
8. 40 minority scientists receive travel fellowships to Experimental Biology 2009 in New Orleans
9. 2 McGill researchers garner prestigious NSERC Steacie Fellowships
10. Two UT Southwestern researchers awarded Sloan fellowships
11. Fifth annual Templeton-Cambridge fellowships awarded to 10 noted journalists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Weatherstone Fellows publish research as Autism Speaks announces 2011 Weatherstone Fellows
(Date:7/9/2014)... July 9, 2014Biofuels derived from the oils produced by ... fuels. To achieve this goal, optimization of cost effective ... pond systems, is needed. Sapphire Energy has developed an ... pond algae cultivation systems, described in Industrial Biotechnology ... publishers. The article is available on the Industrial ...
(Date:7/9/2014)... Cancer Genome Atlas (TCGA) Research Network have identified ... lung adenocarcinoma, the most common subtype of lung ... the number of possible therapeutic targets for this ... patients with treatable mutations because many potent cancer ... TCGA is jointly funded and managed by the ...
(Date:7/9/2014)... era of increasing concern about the prevalence of ... a promising new pathway to disabling disease: blocking ... The scientists showed how bacterial siderophore, a small ... to fan bacterial growth as well as ... this infection process. Their findings appear in a ...
Breaking Biology News(10 mins):Controlling contamination in open algae ponds for biofuels 2Study identifies novel genomic changes in the most common type of lung cancer 2Study identifies novel genomic changes in the most common type of lung cancer 3Bacteria hijack plentiful iron supply source to flourish 2
... American Societies for Experimental Biology (FASEB) announces the opening ... DNA in Mammalian Genomes. Mobile elements have been ... and altering functions within mammalian genomes, and continue to ... explosion of data from high throughput sources, as well ...
... prepared a patient to inhale a panic-inducing dose of carbon ... the mixture, she cried for help, overwhelmed by the sensation ... her 40s known as SM, has an extremely rare condition ... amygdala, an almond-shaped area in the brain long known for ...
... for Experimental Biology (FASEB) announces the opening of registration ... and Flagella. The 2013 Biology of Cilia ... conference where basic and translational research intersect to drive ... ciliopathies. The underlying theme of the 2013 conference is ...
Cached Biology News:Human brain is divided on fear and panic 2Human brain is divided on fear and panic 3
(Date:1/15/2014)... 15, 2014 AudioNotch is the internet's ... for the treatment of tinnitus. Patients listen to sound ... over a period of weeks to months, their tinnitus volume ... two forms: Notched Music and Notched White Noise. Now, AudioNotch ...
(Date:1/14/2014)... January 14, 2014 Carahsoft and CDS ... January 23, 2014 at 2pm EST (11am PST), “Natural ... topic focuses on how technology can turn raw, heterogeneous ... for government agencies. The online webinar will last approximately ...
(Date:1/14/2014)... As pet owners drew up their lists of New Year,s ... better care of my furry companion." Nowadays there are pet salons, ... cases to take the little canine or feline darlings along wherever ... buy some pricey toys at the pet store. But anyone who ...
(Date:1/14/2014)... and BETHESDA, Md. , Jan. ... together with two institutes from the National Institutes of ... for bringing safer, more effective treatments to patients on ... Center for Advancing Translational Sciences (NCATS) and the National ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3
... ... information company that develops and supplies irrigation management solutions. The company was approved for ... irrigation management control where “the plant is the sensor™.” , ... (Vocus) April 30, 2010 -- ...
... BEACH, California , and AMSTERDAM , April ... Meeting of the American Society of Breast,Surgeons, Agendia, a ... Research and Treatment has published an important study,demonstrating the ... breast cancer recurrence according to the MammaPrint test. The,ASBS ...
... April 29  Scotland will showcase the ... the world,s leading pharma and biotech companies to its ... in Chicago .  Heading into the conference, ... the nation,s unique integrated industry approach will continue to ...
Cached Biology Technology:$250,000 Awarded to Smartfield, Inc. of Lubbock, TX by the Texas Emerging Technology Fund 2New Study Demonstrates Patients With High-Risk MammaPrint Profile Benefit From Chemotherapy 2New Study Demonstrates Patients With High-Risk MammaPrint Profile Benefit From Chemotherapy 3Scotland Announces New Life Science Leadership and Investments at BIO 2010 2Scotland Announces New Life Science Leadership and Investments at BIO 2010 3Scotland Announces New Life Science Leadership and Investments at BIO 2010 4
... cytopathic effect inhibition assays, also known as CPE ... culture supernatents; serum from PK studies and delivery ... defined as the quantity of interferon required per ... infection by 50%. All standards used ...
Request Info...
Request Info...
Request Info...
Biology Products: