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Wayne State to study the role of vitamin D in African-Americans with high blood pressure
Date:6/2/2011

pressure.

"Vitamin D's effectiveness in further reducing left ventricle mass would decrease the risk of cardiovascular disease complications in African-Americans," Levy said.

Additionally, if serum markers parallel MRI findings in the study, Levy said, they could then serve as a screening and assessment tool.

Levy will serve as the principal investigator for the study. His research mentor, John Flack, M.D., M.P.H., professor and chair of internal medicine, and Rafael Fridman, Ph.D., professor of pathology, will be co-investigators.

"There are biologically plausible mechanisms through which vitamin D deficiency can cause or contribute to left ventricular hypertrophy," Flack said. "Populations, such as African-Americans, who manifest high rates of vitamin D deficiency also have excessive rates of left ventricular hypertrophy. The test of whether moderate- to high-dose vitamin D replacement can regress left ventricular hypertrophy is long overdue. Vitamin D is safe, reasonably cheap, and has enormous, but mostly unproven, therapeutic potential."


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Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

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