Navigation Links
Wayne State discovers potential treatment for better heart health in hemodialysis patients
Date:1/15/2014

DETROIT Researchers at Wayne State University have discovered a potential way to improve the lipid profiles in patients undergoing hemodialysis that may prevent cardiovascular disease common in these patients. Patients undergoing hemodialysis for kidney failure are at a greater risk for atherosclerosis, a common disease in which plaque builds up inside the arteries. Atherosclerosis can lead to serious problems including heart attack, stroke or even death.

The team of researchers discovered that a unique combination of vitamin E isomers known as tocotrienols improved the patients' lipid profiles. The study, "Vitamin E tocotrienol supplementation improves lipid profiles in chronic hemodialysis patients," was published in a recent issue of the journal, Vascular Health Risk Management, and showed that patients in the randomized double-blind, placebo-controlled parallel trial who were given the vitamin E supplement had notable improvement in their lipid profiles compared to those given the placebo.

"After 12 and 16 weeks of intervention, the hemodialysis patients taking the Vitamin E supplements showed significant improvements in their blood lipid profiles," said Pramod Khosla, Ph.D., associate professor of nutrition & food science in Wayne State University's College of Liberal Arts and Sciences. "Specifically, their triglycerides were reduced and their HDL cholesterol levels increased, as compared to the placebo group."

"This study could potentially have positive clinical implications in the future for hemodialysis patients that need to improve their triglyceride and HDL levels, but first these findings need to be verified in a much larger group of subjects. Additionally, we need to tease out the interactive effects of the tocotrienols with various medications that are routinely prescribed to these patients," added Khosla.

"Accelerated cardiovascular disease is a major problem in the end-stage renal disease population, a
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Wayne State University researchers program targets safer river fishing, anglers health
2. Wayne State researchers working to improve genetic analysis, disorder detection
3. Wayne State receives $2.8 million grant from US Administration for Children and Families
4. New book on physics principles by Wayne State professor explains life as we know it
5. High-strength material advancements at Wayne State University may lead to new, life-saving steel
6. Cancer risk for African-American women with benign breast disease factors Wayne State finds
7. Wayne State University researchers techniques enable more, faster testing of biological liquids
8. Wayne State study shows airborne dust in urban areas impacts lead levels in children
9. Wayne State vision restoration technology receives Notice of Allowance for US patent app
10. Wayne State University startup, Advaita, to participate in new Michigan I-Corps program
11. Wayne State welcomes undergraduates from around the US for physics research experience
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... key molecular cog in a plant,s biological clock ... based on temperature. , Transcription factors, or genetic switches, ... such as light, rain, soil quality, or even ... USC has isolated one, called FBH1, that reacts to ... needed while in keeping it on a consistent track. ...
(Date:9/22/2014)... the Society of Environmental Toxicology and Chemistry (SETAC) held ... prioritize the scientific research needed to understand the risks ... environment. The effort was extended, and results were ... international journal, Integrated Environmental Assessment and Management ... podcast interviewing the lead author of the study, Murray ...
(Date:9/22/2014)... YORK CITY (September 22, 2014)The Brain & ... the award of NARSAD Young Investigator Grants ... 200 of the world,s most promising young ... for groundbreaking neurobiological research will seek to ... strategies for psychiatric disorders that affect one ...
Breaking Biology News(10 mins):Genetic switch regulates a plant's internal clock based on temperature 2Priorities for research on pharmaceutical and personal care products in the environment 2Brain & Behavior Research Foundation awards 200 NARSAD Young Investigator grants 2
... new use as an adjuvant to cancer therapy, providing an ... study published in the Feb. 15 issue of Clinical Cancer ... Gallez, Ph.D., professor of pharmacy at the Université de Louvain ... A into two types of mouse tumors, the tumors' cellular ...
... H5N1 influenza samples in Southeast Asia shows not only ... are related but also that they belong to two ... for Disease Control and Prevention report their findings today ... "As the virus continues its geographic expansion, it is ...
... in Africa declared that a dramatic rise in tuberculosis (TB) ... TB case notifications have increased as much as four-fold over ... HIV. When individuals are infected with both HIV and TB, ... to active TB. , To combat the problem, the ...
Cached Biology News:Botox could help target resistant tumors for treatment 2Botox could help target resistant tumors for treatment 3Study outlines genetic differences between potential pandemic influenza strains 2
(Date:9/22/2014)... This is a professional and in-depth study ... industry in Global and China. The report provides a ... industry chain structure. Global market analysis and Chinese domestic ... developments, trends and competitive landscape of the market. A ... offered. , The report also focuses on development policies ...
(Date:9/22/2014)... , Sept. 22, 2014 Research ... "Global and Chinese Microcrystalline Cellulose Industry Report 2014" ... Global and Chinese Microcrystalline Cellulose Industry Report 2014 is ... of the global microcrystalline cellulose industry with a focus ... a basic overview of the industry including definitions, classifications, ...
(Date:9/22/2014)... N.J. , Sept. 22, 2014  WIRB-Copernicus ... and ethical review services for clinical research, announced ... (WIRB) has been reaccredited by the Association ... (AAHRPP), which endeavors to improve safeguards for clinical ... Donald A. Deieso , Ph.D., commented, "It ...
(Date:9/21/2014)... at the University of Basel in Switzerland have ... a charged molecule for the first time. These ... measurements of molecular properties and may also contribute ... technology. The results were published in the scientific ... study of the interaction between matter and light, ...
Breaking Biology Technology:m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 2m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 3Global and Chinese Microcrystalline Cellulose Industry Report 2014 2Western IRB (WIRB) Awarded AAHRPP Reaccreditation 2Uncovering the forbidden side of molecules 2
... Inc. (OTC Bulletin Board: NWBO ) (NW Bio) joined ... over the course of more than 13 months, the parties ... brain cancer in Germany. As a result, the Company is ... with both its clinical trial program and Hospital Exemption cases ...
... J.D., will offer her expert perspective on  the ... she presents "EHRs: Meaningful Use & Beyond" during ... held  April 24-26, 2012, at the Thelma Keller ... During the presentation, Pita, who serves as executive ...
... facilitated the evolution and complexity of terrestrial organisms, including human ... by those organisms, which in turn were able to generate ... oxygen molecules work inside the body, more attention is being ... to thwart them. A number of environmental ...
Cached Biology Technology:Northwest Bio and Fraunhofer IZI Announce Milestones Reached 2Northwest Bio and Fraunhofer IZI Announce Milestones Reached 3Northwest Bio and Fraunhofer IZI Announce Milestones Reached 4Prognosis HIS Executive Slated To Offer EHR Advice At Illinois Rural Health Association Conference 2Avocado Oil: The 'Olive Oil Of The Americas'? 2Avocado Oil: The 'Olive Oil Of The Americas'? 3Avocado Oil: The 'Olive Oil Of The Americas'? 4
This monoclonal antibody recognizes the light chain of human Factor XII and at 100 nM inhibits 50% of Factor XII activity. It may be used in ELISA to detect human Factor XII and in coagulation assay...
Anti-LC3 Polyclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Rabbit polyclonal to Xanthine Oxidase (HRP) ( Abpromise for all tested applications). Antigen: Xanthine Oxidase (from Bovine Buttermilk) Entrez Gene ID: 7498 Swiss Protein ID: P47989...
Phospho- (Ser) 14-3-3 Binding Motif (4E2) Mouse mAb...
Biology Products: