Navigation Links
Wayne State discovers potential treatment for better heart health in hemodialysis patients
Date:1/15/2014

DETROIT Researchers at Wayne State University have discovered a potential way to improve the lipid profiles in patients undergoing hemodialysis that may prevent cardiovascular disease common in these patients. Patients undergoing hemodialysis for kidney failure are at a greater risk for atherosclerosis, a common disease in which plaque builds up inside the arteries. Atherosclerosis can lead to serious problems including heart attack, stroke or even death.

The team of researchers discovered that a unique combination of vitamin E isomers known as tocotrienols improved the patients' lipid profiles. The study, "Vitamin E tocotrienol supplementation improves lipid profiles in chronic hemodialysis patients," was published in a recent issue of the journal, Vascular Health Risk Management, and showed that patients in the randomized double-blind, placebo-controlled parallel trial who were given the vitamin E supplement had notable improvement in their lipid profiles compared to those given the placebo.

"After 12 and 16 weeks of intervention, the hemodialysis patients taking the Vitamin E supplements showed significant improvements in their blood lipid profiles," said Pramod Khosla, Ph.D., associate professor of nutrition & food science in Wayne State University's College of Liberal Arts and Sciences. "Specifically, their triglycerides were reduced and their HDL cholesterol levels increased, as compared to the placebo group."

"This study could potentially have positive clinical implications in the future for hemodialysis patients that need to improve their triglyceride and HDL levels, but first these findings need to be verified in a much larger group of subjects. Additionally, we need to tease out the interactive effects of the tocotrienols with various medications that are routinely prescribed to these patients," added Khosla.

"Accelerated cardiovascular disease is a major problem in the end-stage renal disease population, a
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Wayne State University researchers program targets safer river fishing, anglers health
2. Wayne State researchers working to improve genetic analysis, disorder detection
3. Wayne State receives $2.8 million grant from US Administration for Children and Families
4. New book on physics principles by Wayne State professor explains life as we know it
5. High-strength material advancements at Wayne State University may lead to new, life-saving steel
6. Cancer risk for African-American women with benign breast disease factors Wayne State finds
7. Wayne State University researchers techniques enable more, faster testing of biological liquids
8. Wayne State study shows airborne dust in urban areas impacts lead levels in children
9. Wayne State vision restoration technology receives Notice of Allowance for US patent app
10. Wayne State University startup, Advaita, to participate in new Michigan I-Corps program
11. Wayne State welcomes undergraduates from around the US for physics research experience
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... Scientists at Washington State University have concluded that ... apples may help prevent disorders associated with ... to assess these compounds in apple cultivars grown ... edition of the journal Food Chemistry ., ... good source of these nondigestible compounds but there ...
(Date:9/29/2014)... review article published online in Behavioral Brain Research ... the brain as a result of chronic alcohol exposure ... , Clinical assessments and research indicate that individuals ... sleep. This can occur when people are actively drinking, ... are abstaining. , "Sleep-wake disturbances can last for ...
(Date:9/29/2014)... of Pangea was starting to break up and dog-sized dinosaurs ... called phytosaurs and rauisuchids were at the top of the ... predators didn,t interact much as the former was king of ... ideas are changing, thanks largely to the contents of a ... in the German journal Naturwissenschaften , Stephanie ...
Breaking Biology News(10 mins):An apple a day could keep obesity away 2Tooth buried in bone shows prehistoric predators tangled across land, sea 2
... MARC (Minority Access to Research Careers) Program has announced the ... of Reproduction (SSR) Annual Meeting in Portland, Oregon from July ... to promote the entry of underrepresented minority students, postdoctorates and ... to encourage the participation of young scientists at the 2011 ...
... lose weight and suspect your body,s working against you, you may ... Obesity . "When obese persons reduce their food intake ... They may have to work harder and go slower in order ... in the U of I College of Medicine and a member ...
... Australia,s fruit and vegetable industry are under threat, ... to find new ways to control a major ... Associate Professor Anthony Clarke, from QUT,s Faculty of ... largest team of university researchers examining non-chemical based ...
Cached Biology News:Obese dieters' brain chemistry works against their weight-loss efforts 2Qld fruit fly scientists in race against time 2Qld fruit fly scientists in race against time 3
(Date:9/29/2014)... food security, emerging diseases and biodiversity loss requires ... in Science Express that was co-authored ... College of Agriculture and Life Sciences. , For ... scientists has reviewed progress in addressing a broad ... management using approaches that consider evolutionary histories and ...
(Date:9/29/2014)... , Sept. 29, 2014 Research ... "Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph Market ... & Region - Global Trends & Forecast to 2013 ... A process analyzer is a process analytical instrument ... real-time. It has redefined the way by which companies ...
(Date:9/29/2014)... Transparency Market Research, in its report titled ‘Peptide ... Application - Cancer, Metabolic, CVS, CNS & others, by ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast, ... market was worth US$14.1 billion in 2011 and is ... 8.7% CAGR. , The two main types of peptide ...
(Date:9/29/2014)... 29, 2014  Atlas Venture, an early stage venture ... innovation, today announced that Jason Rhodes , President ... EPZM ), is joining the firm,s life sciences investing ... At Atlas, Rhodes will work closely with the ... an accomplished record in company creation, deal making and ...
Breaking Biology Technology:Evolutionary biology: It's not just for textbooks anymore 2Evolutionary biology: It's not just for textbooks anymore 3Global Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph (PH/ORP, Chlorine, Oxygen, Carbon dioxide) Market - Trends & Forecast to 2020 2Global Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph (PH/ORP, Chlorine, Oxygen, Carbon dioxide) Market - Trends & Forecast to 2020 3Global Process Liquid Analyzer, Gas Analyzer, and Gas Chromatograph (PH/ORP, Chlorine, Oxygen, Carbon dioxide) Market - Trends & Forecast to 2020 4Global Peptide Therapeutics Market to be Worth US$25.4 Billion by 2018: Transparency Market Research 2Global Peptide Therapeutics Market to be Worth US$25.4 Billion by 2018: Transparency Market Research 3Atlas Venture Names Jason Rhodes, Veteran Investor and President and CFO of Epizyme, As Partner on Life Sciences Investing Team 2
... Inc. (Nasdaq: ENMD ), a clinical-stage pharmaceutical ... inflammatory diseases, announced today that a Company overview will ... Pharmaceuticals Industry Conference, to be held at the Conference ... Dane R. Saglio, Chief Financial Officer, will present ...
... Systems, Inc., (OTC Bulletin Board: IMDS) a pioneer in ... issuance of its,21st US Patent entitled "Apparatus and Method ... Point Spread,Function of the Detected Light," dated November 4, ... http://www.newscom.com/cgi-bin/prnh/20040412/IMDSLOGO ) , ...
... CRY ), a,biomaterials, medical device and tissue processing company, ... Annual Piper Jaffray Health,Care Conference at The New York Palace ... Anderson, president and chief executive officer of CryoLife,Inc., will provide ... 2:30 p.m. Eastern Time. , ...
Cached Biology Technology:EntreMed to Present at the New York Society of Security Analysts Industry Conference 2Imaging Diagnostic Systems is Recognized for Its Advanced Engineering in Time-Resolved Techniques by the US Patent Office 2Imaging Diagnostic Systems is Recognized for Its Advanced Engineering in Time-Resolved Techniques by the US Patent Office 3CryoLife to Present at 20th Annual Piper Jaffray Health Care Conference 2
... EZ-Spread Plating Beads Sterile plating in ... glass rods and potentially hazardous ethanol flaming, ... choices of ready-to-use sterile packaging: dispenser bottle for ... plating, Fastest and easiest way to ...
The new Silencer siRNA Starter Kit is perfect for researchers new to RNAi. It provides all of the reagents, protocols, and instructions necessary to get underway with siRNA transfection and ensure su...
... a regulated environment, Pipette Tracker Pro ... that automates gravimetric pipette calibration and ... meets todays regulatory compliance requirements. Pipette ... that includes a full security implementation, ...
... the yolk protein Vtg in plasma from juvenile ... biomarker for endocrine disrupting chemicals (EDCs) with estrogenic ... an accepted screening test for the estrogenic effects ... EIA kit is a double-antibody immunometric (sandwich) EIA ...
Biology Products: