Navigation Links
Wayne State announces license agreement for breakthrough approaches to vision restoration
Date:10/18/2011

DETROIT RetroSense Therapeutics, LLC, a Michigan-based company, announced that it has executed its exclusive, worldwide option and signed a license agreement for novel gene-therapy approaches for treating blindness developed at Wayne State University's School of Medicine.

Zhuo-Hua Pan, Ph.D., professor of anatomy and cell biology in the School of Medicine, along with colleagues at Salus University in Pennsylvania, developed the breakthrough therapy and follow-on approaches that offer promise to people suffering with incurable blindness caused by age-related macular degeneration (AMD) and retinitis pigmentosa (RP) retinal degenerative disorders that are currently incurable.

AMD is the leading cause of blindness in people older than 60, affecting more than 8 million people in the U.S. alone. Worldwide, 500,000 individuals lose their eyesight annually to AMD, which is the result of progressive deterioration of photoreceptor cells in the macula, the central portion of the retina.

RP is a genetically-determined eye disease caused by mutations in more than 100 different genes. An estimated 100,000 people in the U.S. have RP, which typically manifests as night blindness and progresses to tunnel vision and sometimes complete blindness.

Pan's novel strategy focused on genetically converting light-insensitive inner retinal neurons into photosensitive cells thus restoring light-sensitivity to retinas that lack photoreceptors. Using a virus that delivers a photoreceptor gene from green algae called channelrhodopsin-2 (ChR2), Pan found that ChR2 made the inner retinal neurons become light sensitive, and that it persisted for long periods in the neurons, ultimately leading to restored responses to light in the visual cortex of the brain.

With this technology, combined with the business and drug development expertise of RetroSense's seasoned management team, Pan is hopeful his breakthrough treatment is on the fast track to
'/>"/>

Contact: Julie O'Connor
julie.oconnor@gmail.com
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Genomatix gives a hand in the analysis of Wayne States sequencing projects
2. NextCAT Inc. secures $250,000 to commercialize biodiesel technology developed at Wayne State
3. NextCAT secures license agreement for advanced biofuel technology from Wayne State
4. Soy increases effectiveness of radiation at killing lung cancer, Wayne State study shows
5. Wayne State University chosen as Michigans sole participant in EcoCAR 2
6. Wayne State to study the role of vitamin D in African-Americans with high blood pressure
7. Wayne State researcher discovers antibiotic useful for localized treatment of bone wear
8. Wayne State start-up company NextCAT awarded nearly $500,000 from NSF for Phase II SBIR
9. EPA grants help Wayne State researchers stave off Great Lakes environmental invaders
10. NC State researchers get to root of parasite genome
11. L-1 Identity Solutions Receives $5.9 Million Drivers License Contract Expansion from the State of Mississippi
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... VEGAS , Dec. 18, 2014   LaunchKey , ... for the post-password and Internet of Things era, today ... funding. The venture round was led by Metamorphic Ventures ... Rimrock Venture Partners, VegasTechFund, and others.  LaunchKey has raised ...
(Date:12/17/2014)... Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) has announced the ... report to their offering. ... in this market is the increasing demand for medical ... of patient data for quick and correct diagnosis during ...
(Date:12/11/2014)... N.C. , Dec. 10, 2014  That blood pressure plays ... a while. Hypertension – the medical term for high blood ... early 1800s, and the inflatable cuff that,s used in measuring ... however, mean there,s nothing new about hypertension, its triggers and ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... an iconic Australian lizard species from death at the hands ... March issue of The American Naturalist . It,s an ... the arrival of another, says Richard Shine, a biologist at ... Cane toads were introduced in Australia in the 1930s ...
... rest of the school takes off in fear, tipped off by ... Now, researchers reporting online on February 23 in the Cell Press ... stuff is really made of. Within that chemical brew ... skin. When a fish is wounded, fragments of the sugar known ...
... Most convenience stores have a wide variety of chips, ... can buy calorie-heavy foods wrapped in pretty packages in these ... whole grains and low-fat dairy products necessary for a healthy ... source for millions of Americans living in what are called ...
Cached Biology News:Invasive plant protects Australian lizards from invasive toad: Study 2For fish, fear smells like sugar 2Healthy foods missing from stores in low-income black neighborhoods, UGA study finds 2Healthy foods missing from stores in low-income black neighborhoods, UGA study finds 3Healthy foods missing from stores in low-income black neighborhoods, UGA study finds 4
(Date:12/24/2014)... 2014  Vermillion, Inc. (Nasdaq:   VRML), a bio-analytical ... that the Company closed its previously announced private ... Jack W. Schuler , Birchview Fund LLC and ... before offering expenses.  The proceeds will be used ...
(Date:12/24/2014)... Missouri (PRWEB) December 23, 2014 GMO corn ... company, Syngenta, are in the process of being consolidated in ... is In Re: Syngenta AG MIR 162 Corn Litigation, MDL ... of Kansas. , Management of the Syngenta GMO corn multidistrict ...
(Date:12/24/2014)... December 23, 2014 On Friday, December ... the Omnibus and Continuing Resolution Appropriations Act of 2015, ... eligible to receive funding through the Congressionally Directed Medical ... (DoD). The Hydrocephalus Association (HA), working in conjunction with ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 Nashville Fertility Center ... treasurer for the American Society for Reproductive Medicine (ASRM), a ... reproductive medicine. In his new role as treasurer, Dr. ... will have a voice in furthering the mission of ASRM. ...
Breaking Biology Technology:Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3
... Va., July 8 BSI announced today that ... world,s leading supplier of,recombinant Protein A, a consumable ... growing segment of the biopharmaceutical industry,has achieved BS ... North,America to have achieved certification for their commitment ...
... 8 RADI Medical Systems today,announced improvements ... PressureWire(R) Certus, which will begin shipments immediately., ... The latest generation of the PressureWire(R) Certus ... provides three key,advantages for physicians. The new ...
... China-Biotics,Inc. (OTC Bulletin Board: CHBT) ("China-Biotics," "the ... manufacture, research, development,marketing and distribution of probiotics ... Technology Officer, has been invited to,be the ... Safety Technology Forum,2008 (the "Forum")., The ...
Cached Biology Technology:Presentation of North America's First Certificate for BS 25999, the New Standard for Business Continuity 2Presentation of North America's First Certificate for BS 25999, the New Standard for Business Continuity 3RADI Medical Systems Launches Next Generation PressureWire(R) Certus 2China-Biotics, Inc. to Present at China's 3rd Annual Food Safety Technology Forum 2008 2China-Biotics, Inc. to Present at China's 3rd Annual Food Safety Technology Forum 2008 3
... Exiqons LNA technology enables sensitive, fast and ... intact chromosomes. Short hybridisation time ... cells and chromosome spreads Multiplex capability ... probes Probes available with ...
... Source rat adult and fetal ... $550.00, * T75 plated cells ... * This product requires Celprogen ... M55007-08 and extracellular matrix, * ...
... Isolation Kit provides a rapid method for ... from the various bacterial species found within ... of genomic DNA from both gram negative ... ,Purification is based on spin column ...
...
Biology Products: