Navigation Links
Wayne State University researcher's techniques enable more, faster testing of biological liquids
Date:2/21/2013

itor what is happening inside them. They're so small you can't use conventional tools, so you need some new technology."

The first project, supported by a $335,000 grant through the NSF's Electronics, Photonics and Magnetic Devices program, will investigate what Basu calls a novel approach for controlling the motion of droplets using lasers. Titled "Optofluidic Tweezers" (OFT), the project focuses on a technique that can generate forces 100,000 times larger than traditional optical tweezers. The technology, recently patented by Wayne State's Technology Commercialization Office, enables novel applications in microscale liquid control, particle manipulation and light-directed assembly.

OFT uses Marangoni flow, a surface tension-driven phenomenon that becomes more powerful at a small scale.

Basu uses the Marangoni effect to grab a droplet on the axis of a focused laser, resulting in a class of optical tweezers that can trap and manipulate liquid droplets with large force. By scanning the laser in two dimensions, he can move droplets as needed for liquid handling.

The second project, "Tensiophoresis: Label Free Droplet Sorting in Surfactant Microgradients," funded by a $301,000 grant, is jointly supported by NSF programs in Particulate and Multiphase Processes and Chemical and Biological Separations.

A key operation in droplet assays is the ability to detect chemicals in droplets. Tensiophoresis uses the phenomenon of capillary migration to sort droplets based on their chemical composition, without the fluorescent labels typically required in such assays.

In tensiophoresis, a droplet is placed in a small channel between two liquid streams with different interfacial tensions (IFT). Capillary migration causes the droplet to swim into one of the two streams, enabling researchers to sense and sort proteins within droplets for proteomic applications.

"The ability to sort droplets by their IFT is particularly i
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Wayne State University researchers program targets safer river fishing, anglers health
2. Wayne State researchers working to improve genetic analysis, disorder detection
3. Wayne State receives $2.8 million grant from US Administration for Children and Families
4. New book on physics principles by Wayne State professor explains life as we know it
5. High-strength material advancements at Wayne State University may lead to new, life-saving steel
6. Cancer risk for African-American women with benign breast disease factors Wayne State finds
7. Marshall University study may lead to new treatments for prostate cancer
8. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
9. Carnegies Greg Asner named Energy/Climate Fellow by US State Department
10. Planet under Pressure conference, London: Final statement
11. Tokai Pharmaceuticals galeterone well-tolerated in patients with advanced prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Wayne State University researcher's techniques enable more, faster testing of biological liquids
(Date:8/22/2014)... news release is available in German . ... helper substances, in PCFs proteins are fixated in a ... stable crystals. Next, the HZB and Fudan University researchers ... used as functional materials. Their findings are being published ... (DOI: 10.1038/ncomms5634). , Proteins are sensitive molecules. Everyone knows ...
(Date:8/22/2014)... of the birds and the bees. But that ... being fertilized. The fertilization process for flowering plants ... the male and female reproductive cells. New research ... and Munich, and including Carnegie,s Wolf Frommer, David ... chemical signaling process that guides flowering plant fertilization. ...
(Date:8/21/2014)... in near darkness use a previously unknown process for ... team led by a Penn State University scientist has ... aimed at improving plant growth, harvesting energy from the ... on Lake Erie and other lakes worldwide. A paper ... Science Express edition of the journal Science ...
Breaking Biology News(10 mins):Proteins: New class of materials discovered 2Calcium and reproduction go together 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 3
... chromosomes 2 and 4 has detected the largest "gene ... evidence that human chromosome 2 arose from the fusion ... National Human Genome Research Institute (NHGRI), part of the ... a study published in the April 7 issue of ...
... Affairs Greater Los Angeles Healthcare System conducted the largest ... current modern drugs for treating hepatitis B -- a ... May 17 Annals of Internal Medicine, the study may ... that a degree of uncertainly exists on how to ...
... viruses spread through the internet is helping ecologists to ... in the British Ecological Society's Journal of Applied Ecology, ... the spiny water flea - a native of Russia ... Ecologists Jim Muirhead and Professor Hugh MacIsaac of the ...
Cached Biology News:Scientists analyze chromosomes 2 and 4 2Scientists analyze chromosomes 2 and 4 3UCLA study assesses cost-effectiveness of Hepatitis B drugs 2UCLA study assesses cost-effectiveness of Hepatitis B drugs 3Internet viruses help ecologists control invasive species 2
(Date:8/22/2014)... The first direct observations of how facets form ... towards more sophisticated and effective nanocrystal design and ... describing crystal growth breaks down at the nanoscale. ... (DOE),s Lawrence Berkeley National Laboratory (Berkeley Lab) used ... high-resolution, fast-detection camera to capture the physical ...
(Date:8/22/2014)... 22, 2014 Research and Markets ... China Gel Permeation Chromatography (GPC) Industry Report 2014" ... and China Gel Permeation Chromatography (GPC) Industry Report is ... of the global gel permeation chromatography industry with a ... a basic overview of the industry including definitions, classifications, ...
(Date:8/22/2014)... August 22, 2014 The identification ... organisms can be accelerated by exome sequencing. Built ... technologies, the custom SeqCap EZ Developer system has ... Mr. Watson will additionally present how he achieved ... available human and mouse exome kits. With over ...
(Date:8/21/2014)... Institute for Molecular Medicine Finland (FIMM), University of ... novel "man and machine" decision support system for ... described in PLOS One scientific journal ... computer vision algorithms similar to those used in ... the diagnostically most relevant areas. Tablet computers can ...
Breaking Biology Technology:Shaping the future of nanocrystals 2Shaping the future of nanocrystals 3Shaping the future of nanocrystals 4Global and China Gel Permeation Chromatography (GPC) Industry Report 2014 2Efficient Identification of Protein-Coding Variants in a Model Organism Through Exome Sequencing, New Webinar Hosted by Xtalks 2A novel 'man and machine' decision support system makes malaria diagnostics more effective 2
... . - Merge Healthcare , a provider of ... designed to overcome challenges posed by the fusing of ... several product upgrades this year as it attempts to ... product accommodates standard image reading methods obtained by PET ...
... Part II of a three-part series on the information technology ... this segment will offer a look at what Wisconsin companies ... IT worker shortage. , , Milwaukee, Wis . - ... information technology positions will go unfilled this year, and then ...
... . - John Gee knows the Bay Area and Silicon ... apply its own value proposition to building a thriving technology ... has been named president and CEO of the Information ... William C. Mortimore, who has been serving in place of ...
Cached Biology Technology:IT workforce development: A little workforce planning goes a long way 2IT workforce development: A little workforce planning goes a long way 3IT workforce development: A little workforce planning goes a long way 4IT workforce development: A little workforce planning goes a long way 5Wisconsin IT association names Gee president, CEO 2
... Time-resolved microscopy is the ultimate tool ... subcellular structures. Its applications previously have been ... because microscope optics do not transmit in ... leader in fluorescence spectroscopy, introduces a filter-based ...
... using many of the automation concepts from ... requirements are similar to those for HTS: ... 24 or 48 wells with well volumes ... the number of wells has increased to ...
... Dermal Fibroblasts (Mouse/BalbC) and media. This cell ... and is guaranteed to provide an additional ... date supplied, when used with the recommended ... 18.5 ,Applications: ,Cultivation: Plate at ...
... Sphingobeads are designed for protein ... characterize sphingosine binding proteins. An ... mL of agarose beads with ... through the terminus of the ...
Biology Products: