Navigation Links
Wayne State University researcher's model will target causes of everyday MS symptoms
Date:2/14/2012

ve functions are based.

"Changes in gray matter could well be associated with emotional outbursts," Gow said. "Cells involved in memory and learning are also being destroyed. Whenever those sorts of changes occur, you almost always see frustration in patients as they try to grapple with the resultant loss in mental capacity.

"That causes them to be upset about not being able to do things, even if they don't know that's what's going on physically. This can also lead to them withdrawing from social settings with family and friends, which deepens the impact of MS."

MS patients' more severe symptoms result when the immune system attacks the myelin that surrounds white matter cells, causing lesions that are visible in magnetic resonance imaging scans. Myelin is a soft, white coating of nerve fibers composed of fats and protein that serves as insulation and as an aid to efficient nerve fiber conduction. When myelin is damaged in MS, nerve fiber conduction is faulty or absent, resulting in impaired bodily functions or altered sensations.

Gow said if viewed the right way, lesions also can be seen in gray matter, indicating that neurons and not just oligodendrocytes are being destroyed.

"That then gives us an anatomical basis for memory loss and patients' inability to focus," Gow said.

Because many brain pathways in Gow's model system are similar to those of humans, he is working to understand what happens when gray matter cells are destroyed as a consequence of the body's immune system. The grant will be used to look for more defined lesions in both white and gray matter when myelin is attacked.

Researchers then will look for behavioral changes similar to those seen in MS patients. They will examine white matter for specific changes indicating the presence of biomarker substances that cause MS-like symptoms. If those substances are found, researchers then can try to administer drugs to reverse the effects of th
'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Genomatix gives a hand in the analysis of Wayne States sequencing projects
2. NextCAT Inc. secures $250,000 to commercialize biodiesel technology developed at Wayne State
3. NextCAT secures license agreement for advanced biofuel technology from Wayne State
4. Soy increases effectiveness of radiation at killing lung cancer, Wayne State study shows
5. Wayne State University chosen as Michigans sole participant in EcoCAR 2
6. Wayne State to study the role of vitamin D in African-Americans with high blood pressure
7. Wayne State researcher discovers antibiotic useful for localized treatment of bone wear
8. Wayne State start-up company NextCAT awarded nearly $500,000 from NSF for Phase II SBIR
9. EPA grants help Wayne State researchers stave off Great Lakes environmental invaders
10. Wayne State announces license agreement for breakthrough approaches to vision restoration
11. Better CMT outcome measurement is Wayne State University physicians goal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... , May 22, 2015 According ... by Solution (2D, 3D, Thermal, Emotion, Forensic), by Software (Middleware, ... (Government and Utilities, Consumer and Home) - Global Forecast ... grow from $2.77 Billion in 2015 to $6.19 Billion ... Browse 79 market data Tables and   43 ...
(Date:5/20/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... 3D-ID LLC, a company engaged in biometric identification is ... technology portion of the recently awarded TIES (Technical Information ... the Army. 3D-ID LLC has a suite ... enforcement and security agencies. Gino Pereira ...
(Date:5/18/2015)... GOTHENBURG, Sweden , May 18, 2015 ... touch fingerprint sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from ... place from June until and including Q3 2015 and the ... Asia . Communicated order values for 2015 hereby amount ... revenues for Q1 2015 of 140 MSEK and a number ...
Breaking Biology News(10 mins):Facial Recognition Market Worth $6.19 Billion by 2020 2Facial Recognition Market Worth $6.19 Billion by 2020 3NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2
... Oct. 20 DigitalPersona, Inc., a leader in ... WAND Corporation, a leading supplier of point-of-sale (POS) ... into their NextGen POS and Classic POS solutions. ... to boost cashier accountability and deter unauthorized manager ...
... COLUMBIA, Mo. Pairing a new approach to prepare ... to genotype a cow, an MU animal scientist, along ... accurate and widespread "family tree" for cows and other ... This genetic information could allow scientists to understand the ...
... at the Smithsonian Tropical Research Institute in Panama has ... to monitor the spread of chytridiomycosisone of the deadliest ... fungus, Batrachochytrium dendrobatidis , this disease is probably ... since the 1970s. During the past decade, the epidemic ...
Cached Biology News:WAND Point-of-Sale Solutions Integrate U.are.U(R) Fingerprint Biometrics From DigitalPersona for Quick-Service Restaurants 2WAND Point-of-Sale Solutions Integrate U.are.U(R) Fingerprint Biometrics From DigitalPersona for Quick-Service Restaurants 3MU research team establishes family tree for cattle, other ruminants 2Catching a killer one spore at a time 2
(Date:5/21/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/84975r/2015_global ) ... Global Survey on Flow Cytometry Adoption Trends" ... goal of this research is to analyze the ... information the survey seeks to collect include factors ... used applications for flow cytometers, respondents, most preferred ...
(Date:5/21/2015)... Ontario (PRWEB) May 21, 2015 ... into an exclusive North American distribution agreement with ... testing system. , With more than 160 years ... products and services for laboratory and production facilities, ... operational excellence and differentiated services to enable science. ...
(Date:5/20/2015)... SAN FRANCISCO, Calif. , May 20, 2015 ... VCYT ) today presented preliminary data demonstrating the ... distinguish idiopathic pulmonary fibrosis (IPF) from other interstitial ... The findings suggest the classifier,s potential to help ... surgery to resolve ambiguity in IPF diagnosis – ...
(Date:5/20/2015)... This year has been one of the harshest ... Pearl’s Premium Ultra Low Maintenance Lawn Seed comes to ... coming out of record bad weather. Offering new ... concerns related to water, health, and climate change, Pearl's ... the standard, water-wasting, chemical-treated standard lawn. Many homeowners ...
Breaking Biology Technology:Global Survey on Flow Cytometry Adoption Trends 2015 2Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 3Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 4Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 5Breakthrough 4th Generation Low Maintenance Lawn Seed Offers Solution to California Drought 2
... Mass., May 6 Caliper Life,Sciences, Inc. (Nasdaq: ... at the,Deutsche Bank,s 33rd Annual Health Care Conference ... 7 at 8:50 a.m. EDT. Kevin,Hrusovsky, President and ... on the,company,s business. The live webcast can be ...
... "Clear to Drive" Campaign Urges Allergy Sufferers to Check Medicine ... Warnings Before Getting Behind the Wheel, KENILWORTH, N.J., May ... trips to the beach. But,the warmer weather also marks a ... season. According to a recent survey, seven out,of ten Americans ...
... the first ... ... dollars, QUEBEC CITY, May 6 /PRNewswire-FirstCall/ - Atrium Innovations Inc.,(TSX: ATB), ... and nutrition industries, announced today,his financial results for the first quarter of ...
Cached Biology Technology:Actress and Mom Lori Loughlin Raises Awareness About the Potential Dangers of Drowsy Driving During Allergy Season 2Actress and Mom Lori Loughlin Raises Awareness About the Potential Dangers of Drowsy Driving During Allergy Season 3Atrium shows a strong financial performance for its first quarter 2Atrium shows a strong financial performance for its first quarter 3Atrium shows a strong financial performance for its first quarter 4Atrium shows a strong financial performance for its first quarter 5
... Detection System is intended for use in ... by an in-house validated in vitro nucleic ... interest. • The ... hybridization capture assay designed to detect amplified ...
... description: Dish uses include large-scale colony-counting and ... PBA Flexys TM automated colony picking ... a new product number, created to easily ... availability yet, please order under the old ...
... PhageMaker System is optimized for maximum packaging efficiencies ... any bacteriophage l vector. Using a test insert ... pfu/g arms (> 4 x 10^8 pfu/g ligated ... system is extremely easy to use; simply add ...
BD BioCoat Collagen IV 150 mm Culture Dishes...
Biology Products: