Navigation Links
Waste from gut bacteria helps host control weight, UT Southwestern researchers report
Date:10/17/2008

DALLAS Oct. 17, 2008 A single molecule in the intestinal wall, activated by the waste products from gut bacteria, plays a large role in controlling whether the host animals are lean or fatty, a research team, including scientists from UT Southwestern Medical Center, has found in a mouse study.

When activated, the molecule slows the movement of food through the intestine, allowing the animal to absorb more nutrients and thus gain weight. Without this signal, the animals weigh less.

The study shows that the host can use bacterial byproducts not only as a source of nutrients, but also as chemical signals to regulate body functions. It also points the way to a potential method of controlling weight, the researchers said.

"It's quite possible that blocking this receptor molecule in the intestine might fight a certain kind of obesity by blocking absorption of energy from the gut," said Dr. Masashi Yanagisawa, professor of molecular genetics at UT Southwestern and a senior co-author of the study, which appears online in Proceedings of the National Academy of Sciences.

Humans, like other animals, have a large and varied population of beneficial bacteria that live in the intestines. The bacteria break up large molecules that the host cannot digest. The host in turn absorbs many of the resulting small molecules for energy and nutrients.

"The number of bacteria in our gut far exceeds the total number of cells in our bodies," said Dr. Yanagisawa.

"It's truly a mutually beneficial relationship. We provide the bacteria with food, and in return they supply energy and nutrients," he explained.

Using mice, the researchers focused on two species of bacteria that break up dietary fibers from food into small molecules called short-chain fatty acids. Dr. Yanagisawa's team previously had found that short-chain fatty acids bind to and activate a receptor molecule in the gut wall called Gpr41, although litt
'/>"/>

Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Central targets may hinder wider waste management objectives
2. Great potential to improve collection, recycling of Europes electronic waste, says UN report
3. Where does stored nuclear waste go?
4. Managing nuclear wastes for the millennia
5. U of Minnesota researchers discover key for converting waste to electricity
6. Key to using local resources for biomass may include waste
7. Dental chair a possible source of neurotoxic mercury waste
8. Wakame waste
9. Research yields pricey chemicals from biodiesel waste
10. Improving swine waste fertilizer
11. New UGA biomass technology dramatically increases ethanol yield from grasses and yard waste
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Waste from gut bacteria helps host control weight, UT Southwestern researchers report
(Date:4/23/2014)... away from using triclosan as an antimicrobial ingredient in ... now scientists are reporting new evidence that appears to ... journal Chemical Research in Toxicology , found that ... promoted the growth of human breast cancer cells in ... Kyung-Chul Choi and colleagues note that hormonal imbalances seem ...
(Date:4/23/2014)... of the family of bacteria that causes whooping ... reveals surprising findings about the bacteria,s origin and ... strategies to control this respiratory disease, which kills ... of 343 strains of the Bordetella pertussis ... the last 100 years illustrates how vaccination has ...
(Date:4/23/2014)... April 23, 2014 A biomedical engineer at the ... innovative technology to make blood transfusions safer. His work ... National Institutes of Health (NIH). , Blood transfusions ... of modern medicine,s absolute necessities. Without them, for instance, ... transfusions are perfect, however. There,s strong evidence that transfusions ...
Breaking Biology News(10 mins):In lab tests, the antimicrobial ingredient triclosan spurs growth of breast cancer cells 2Impact of whooping cough vaccination revealed 2UH biomedical engineer works to make blood transfusions safer 2UH biomedical engineer works to make blood transfusions safer 3
... German . , The latest development by ... porous electrodes of lithium-ion batteries more rapidly with liquid electrolyte, ... in trees. The new process increases the throughput of battery ... be presented by KIT at the eCarTec International Electromobility Fair ...
... breastfed babies initially awaken more during the night for ... and total sleep time -- stabilize in later infancy ... abstract presented Monday, Oct. 17, at the American Academy ... In the study, "Long-Term Relationship Between Breastfeeding ...
... the most diverse ecosystems on the planet, second only ... hystrix ) is common throughout the Indo-Pacific and is ... there is little gene flow between the coral populations ... which provide energy for the corals to survive, are ...
Cached Biology News:Battery research: Bionics reduces filling time 2Deep-reef coral hates the light, prefers the shade 2
(Date:1/15/2014)... JOLIET, Ill. , Jan. 15, 2014  Bill Jacobs Automotive, ... , is teaming up with the Heartland Blood Center ... annual blood drive. The drive takes place Saturday, Jan. 18 ... a.m. - 2 p.m. (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  ...
(Date:1/15/2014)... Calif. (PRWEB) January 15, 2014 Cynvenio, ... and management through the genomic analysis of tumor cells ... Therapy Finder™, a web-based cancer decision support application powered ... option with Cynvenio’s ClearID™ genomic test, Therapy Finder will ...
(Date:1/15/2014)... IPSWICH, England , January 15, 2014 ... to win races on the Formula 1 track could help ... between McLaren Applied Technologies (MAT), Stowhealth (a GP surgery based ... funded by healthcare provider Simplyhealth. Telemetry technology, which ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 DTS Language ... its Online Web Portal for Life Science organizations who need ... specify the subject matter of their documents in advance with ... help reduce time-to-delivery of translations, often a critical factor in ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4DTS Improves Efficiency for Life Science Document Translations 2
... Using bacteria to generate energy is a signifiant step ... University of East Anglia (UEA). Published today by ... Academy of Sciences (PNAS), the research demonstrates for ... proteins which enable bacterial cells to transfer electrical charge. ...
... 23, 2011 DATATRAK International, Inc. (OTCQX: DATA), a ... for the clinical trials industry, today announced the Company,s ... for the second consecutive year. "Being ... the hard work and dedication DATATRAK and its employees ...
... In the computer displays of medical equipment in hospitals ... major role. But a discovery reported from the University ... which have been found to change their ordering and ... low concentrations of a particular bacterial lipid, might find ...
Cached Biology Technology:Discovery opens the door to electricity from microbes 2DATATRAK Recognized as 2011 Crain's Leading EDGE Award Winner 2Liquid crystal droplets discovered to be exquisitely sensitive to an important bacterial lipid 2Liquid crystal droplets discovered to be exquisitely sensitive to an important bacterial lipid 3
...
The 50 ml Magnetic Separation Rack is designed to be used for small-scale separations using magnetic particles. ,Capacity: four 50 ml tubes. ,Magnets: Neodymium rare earth permanent magnets....
...
...
Biology Products: