Navigation Links
Want to slow aging? New research suggests it takes more than antioxidants
Date:7/6/2010

Don't put down the red wine and vitamins just yet, but if you're taking antioxidants because you hope to live longer, consider this: a new study published in the June 2010 issue of the journal GENETICS (http://www.genetics.org) casts doubt on the theory that oxidative stress to our tissues shortens lifespan. That's because researchers from McGill University in Canada have identified mutations in 10 different genes of worms (genes believed to have counterparts in humans) that extend their lifespan without reducing the level of oxidative stress the worms suffer. The results contradict the popular theory that production of toxic reactive oxygen species in tissues is responsible for aging.

"We hope that our study will help in tempering the undue emphasis put on the notion that oxidative stress causes aging and thus that antioxidants could combat aging," said Siegfried Hekimi, Ph.D, the senior author of the study from the Department of Biology at McGill University in Montreal. "We also hope that the genes we have discovered can be used in the future to modulate energy metabolism in a way that can help delay the health issues linked to aging, and possibly increase lifespan itself."

To make their discovery, the scientists exposed a passel of worms (Caenorhabditis elegans) to a chemical that causes random changes in its DNA, and looked among the mutagenized worms for those appearing to have a slow rate of metabolism, manifested in their slow development and slow behavioral responses. They then identified the mutations in these worms that caused this effect, revealing 10 distinct genes involved in metabolism. The scientists' expected that the slowly metabolizing worms would have less oxidative stress, but to the investigators' surprise that was not the case. This suggests that a slow rate of living and reduced energy metabolism is sufficient to increase longevity, even when oxidative stress is not reduced.

"It looks like there's more truth to the clich, 'slow and steady wins the race,' than we imagined," said Mark Johnston, Editor-in-Chief of the journal GENETICS. "This research suggests that if we just eat less, we may not have to suffer eating all that broccoli simply for its antioxidants."


'/>"/>

Contact: Tracey DePellegrin Connelly
td2p@andrew.cmu.edu
412-268-1812
Genetics Society of America
Source:Eurekalert

Related biology news :

1. Hips dont lie: Researchers find more accurate technique to determine sex of skeletal remains
2. WSU researchers use super-high pressures to create super battery
3. Cell signaling classification system gives researchers new tool
4. Ethical issues ignored in teaching, research of sustainability
5. Reprogrammed human blood cells show promise for disease research
6. New book provides summary of research into the origins of life on Earth
7. Depressed mice could aid research on drug-resistant depression in humans
8. NY state the focus of Congressional hearing on how research and innovation fuel local economies
9. DOE awards UC San Diego consortium $9 million for algal biofuels research
10. Researchers discover how insulin-producing cells increase during pregnancy
11. Researchers develop accurate way to predict the age when women will hit the menopause
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2016)... , January 22, 2016 /PRNewswire/ ... announced the addition of the  "Global ... their offering. --> http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ... the  "Global Behavioral Biometric Market 2016-2020" ... Research and Markets ( http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ) ...
(Date:1/20/2016)... Minn. , Jan. 20, 2016   MedNet ... supports the entire spectrum of clinical research, is pleased ... 2015. MedNet,s significant achievements are the result of the ... iMedNet eClinical , it,s comprehensive, easy-to-use ... --> --> Key MedNet growth achievements ...
(Date:1/13/2016)... ALBANY, New York , January 13, 2016 /PRNewswire/ ... Transparency Market Research has published a new market report ... Share, Growth, Trends, and Forecast, 2015 - 2023. According to ... mn in 2014 and is anticipated to reach US$1,625.8 ... from 2015 to 2023. In terms of volume, the ...
Breaking Biology News(10 mins):
(Date:2/6/2016)... Virginia (PRWEB) , ... February 06, 2016 , ... ... E-mail: amitchell(at)cee(dot)org , The Center for Excellence in Education Sponsors Teacher Training ... VA – February 4, 2016 – The Center for Excellence in Education (CEE) ...
(Date:2/5/2016)... 5, 2016 Australian-US drug discovery and development company, ... appointment of a new Chairman, Mr John O,Connor , ... immediately. James Garner , has also been ... former Acting CEO, Mr Iain Ross , will resume ... --> James Garner , has also been formally appointed ...
(Date:2/4/2016)... Falls Church, VA (PRWEB) , ... ... ... a first-year cybersecurity conference presented by Bloomsburg University’s Digital Forensics Club, takes ... Bloomsburg, PA. The two-day event features 20+ speakers and activities such as ...
(Date:2/4/2016)... EDISON, N.J. , Feb. 4, 2016 ... company focused on the development and commercialization of targeted ... BIO CEO & Investor Conference 2016, to be held ... and Source Capital Group,s 2016 Disruptive Growth & Healthcare ... on February 10-11, 2016. James Sapirstein ...
Breaking Biology Technology: