Navigation Links
WUSTL wins $ 2.2 million US Department of Energy grant to build a fuel producing bacterium
Date:10/13/2011

on to the reductionism that has long characterized biology but is increasingly unable to deal effectively with the outpouring of new data.

A systems biology approach integrates layers of information contained in large data sets that identify the molecules important to a cell's metabolism and their interactions. The study of each layer of information is a discipline in itself; together they are informally called the "omics." Pakrasi's team, for example, plans to include cyanobacterial phenomics, genomics, transcriptomics and metabolomics within the sweep of their study.

"Although it might seem that systems biology would lead to information overload," says Pakrasi, "the goal is to locate the control points, or the hubs in the network where many pathways intersect. This actually gives scientists much finer control over the organism than if they were to reach in blindly and replace one node without understanding what role that node plays in the complex network that gives the organism its robustness and resilience."

"It all depends on the questions you ask of the data," Pakrasi says. "You want to know the important things, just as, when you look at a car, you want to know first how many cylinders it has, not how many nuts and bolts."

The second step in the process, synthetic biology, gained notoriety when Craig Venter of human genome fame announced in May 2010 that his team had created the first synthetic bacterium. Since Venter's team put newly constructed parts into existing but empty cells of brewer's yeast (Saccharomyces cerevisiae), some said the organism was not entirely new and so couldn't claim the title of the first entirely synthetic organism.

In fact, however, synthetic biology is an elastic discipline that includes any attempt to design and construct biological functions or systems not found in nature.

Pakrasi's team plans to take a similar approach. In their case the "chassis," as Pakrasi call
'/>"/>

Contact: Diana Lutz
dlutz@wustl.edu
314-935-5272
Washington University in St. Louis
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. WUSTL scientist wins prestigious Presidential Early Career Award
2. 3 WUSTL faculty named AAAS Fellows
3. WUSTLs Living Learning Center shares the worlds first full Living Building certification
4. UofL researcher awarded $2.6 million NIH grant renewal
5. Einstein College of Medicine given $6.7 million to study congenital heart defect genetics
6. UCSB awarded $15 million by Dow to establish collaborative institute for materials research and education
7. UMass Amherst wins major grant to host $7.5 million Northeast Climate Science Center
8. Lab receives $3 million for BioAMS instrument
9. Lithium-sulfur battery research receives $5 million from DOE
10. A living species of aquatic beetle found in 20-million-year-old sediments
11. A new species of fossil silky lacewing insects that lived more than 120 million years ago
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
WUSTL wins $ 2.2 million US Department of Energy grant to build a fuel producing bacterium
(Date:8/27/2014)... -- Duke University researchers have identified a gene that ... OSCA1, encodes a protein in the cell membrane of ... the plant,s water conservation machinery accordingly. , "It,s ... professor of biology at Duke. , The findings, ... , could make it easier to feed the world,s ...
(Date:8/27/2014)... neural circuits in the brain of mice, scientists ... The research, led by Howard Hughes Medical Institute ... Technology (MIT), reveals that the connections between the ... about an experience and the part of the ... experience are malleable. , Altering those connections ...
(Date:8/27/2014)... is entering what is described by the Volunteer Wildfire ... The Eastern Cape provincial government warned residents in certain ... winds and veld fires. A high veld fire ... along the coast in the Great Kei and Mnquma ... and during thunderstorms. The thunderstorms bring lightning strikes ...
Breaking Biology News(10 mins):Water 'thermostat' could help engineer drought-resistant crops 2Researchers change the emotional association of memories 2Researchers change the emotional association of memories 3Researchers change the emotional association of memories 4
... the Smiley lab at the Trudeau Institute have now identified ... be used as a vaccine. This single "subunit" could potentially ... cell-stimulating plague vaccine. The new data is featured in the ... "To date, there has been little progress in the development ...
... the next big innovation in sustainable climate technology? ... for Business Law and Regulation at Case Western Reserve ... do just that. "Technology-induced prizes have a long ... on a Climate Prize Rewarding Energy Innovation to Achieve ...
... Highlights: Advanced technologies create ... Radio was integrated easily with Army,s cellular biometric network ... Harris Corporation,s (NYSE: HRS ... infrastructure for various mission scenarios at the Empire Challenge 2011 ...
Cached Biology News:Trudeau Institute announces new discovery in battle against plague and bacterial pneumonias 2CWRU law professor eyes prize-based incentives to generate climate innovation 2Harris Corporation's Highband Networking Radio Provides Mobile, Wideband Communications for Empire Challenge 2011 2Harris Corporation's Highband Networking Radio Provides Mobile, Wideband Communications for Empire Challenge 2011 3
(Date:8/28/2014)... 28, 2014  Armetheon, Inc. ( www.armetheon.com ), ... to late-stage cardiovascular drug candidates, today announced that ... round of financing. The Series A round was ... with participation from investors that included Atheneos Capital ... Larry Hsu , the founder of Impax ...
(Date:8/28/2014)... PrimeSource Building Products, Inc., a ... SoundConnect to support their communication needs with ... web conferencing platform GlobalMeet powered by SoundConnect. The ... SoundConnect delivers award winning “results driven” business ... will be utilizing GlobalMeet powered by SoundConnect ...
(Date:8/27/2014)... 2014 Rhythm, a biopharmaceutical company developing peptide ... result in metabolic disorders, announced today that it has ... U.S. Securities and Exchange Commission (SEC) relating to the ... stock. The number of shares to be offered and ... been determined. Citigroup and Cowen and Company ...
(Date:8/27/2014)... The Global and China Trifluoroacetic Acid Industry ... state of the Trifluoroacetic Acid industry in Global and ... the industry, including definitions, applications and industry chain structure. ... provided with a focus on history, developments, trends and ... international and Chinese situation is also offered. , The ...
Breaking Biology Technology:Armetheon Completes $7.0 Million Series A Financing 2Armetheon Completes $7.0 Million Series A Financing 3PrimeSource Chooses SoundConnect as Collaboration Provider 2Rhythm Files Registration Statement for Proposed Initial Public Offering 2Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2
... educated nearly 80,000 patients in over 30 states on ... disease and treatment options since 1997, DEERFIELD, Ill., ... Baxter Healthcare Corporation,s Kidney Patient,Educator (KPE) program, an ambitious ... disease (CKD) and treatment options to,nearly 80,000 kidney disease ...
... at 11:45 am ET on November 8, 2007, ... (Nasdaq: TARG ) today announced its participation,in ... Conference, taking place November 8, 2007 at the,Hilton ... Officer of Targanta, will be presenting at 11:45 ...
... MNKD ) today announced results from a ... GLP-1 (glucagon-like peptide) on Technosphere,particles that is delivered ... as an open-label, dose escalation, controlled safety and,tolerability ... was assigned to one of five dose levels ...
Cached Biology Technology:Baxter Kidney Patient Education Program Celebrates Tenth Anniversary 2Baxter Kidney Patient Education Program Celebrates Tenth Anniversary 3Baxter Kidney Patient Education Program Celebrates Tenth Anniversary 4Targanta to Present at 9th Annual Mass Opportunities Investment Conference 2MannKind Announces Positive Results from a Phase 1a Study of a GLP-1 Formulation 2MannKind Announces Positive Results from a Phase 1a Study of a GLP-1 Formulation 3MannKind Announces Positive Results from a Phase 1a Study of a GLP-1 Formulation 4
... ViaSure Kit is used in conjunction with the ... cells automatically. The ViaSure Staining Reagent uses ... Acridine Orange and Ethidium Bromide to identify live ... while the EasyCount Slide 6 Multi-well Slide ...
... The Mini Trans-Blot cell and PowerPac Basic power ... to membranes. The Mini Trans-Blot cell accommodates two ... gel holder cassettes, modular electrode assembly, Bio-Ice cooling ... 4 fiber pads. The PowerPac basic power supply, ...
...
... SPE is a powerful, high-throughput workstation dedicated specifically for automating Solid Phase Extraction ... large volumes aqueous solution extractions (up to 2000ml's). ... ... ...
Biology Products: