Navigation Links
WUSTL wins $ 2.2 million US Department of Energy grant to build a fuel producing bacterium
Date:10/13/2011

on to the reductionism that has long characterized biology but is increasingly unable to deal effectively with the outpouring of new data.

A systems biology approach integrates layers of information contained in large data sets that identify the molecules important to a cell's metabolism and their interactions. The study of each layer of information is a discipline in itself; together they are informally called the "omics." Pakrasi's team, for example, plans to include cyanobacterial phenomics, genomics, transcriptomics and metabolomics within the sweep of their study.

"Although it might seem that systems biology would lead to information overload," says Pakrasi, "the goal is to locate the control points, or the hubs in the network where many pathways intersect. This actually gives scientists much finer control over the organism than if they were to reach in blindly and replace one node without understanding what role that node plays in the complex network that gives the organism its robustness and resilience."

"It all depends on the questions you ask of the data," Pakrasi says. "You want to know the important things, just as, when you look at a car, you want to know first how many cylinders it has, not how many nuts and bolts."

The second step in the process, synthetic biology, gained notoriety when Craig Venter of human genome fame announced in May 2010 that his team had created the first synthetic bacterium. Since Venter's team put newly constructed parts into existing but empty cells of brewer's yeast (Saccharomyces cerevisiae), some said the organism was not entirely new and so couldn't claim the title of the first entirely synthetic organism.

In fact, however, synthetic biology is an elastic discipline that includes any attempt to design and construct biological functions or systems not found in nature.

Pakrasi's team plans to take a similar approach. In their case the "chassis," as Pakrasi call
'/>"/>

Contact: Diana Lutz
dlutz@wustl.edu
314-935-5272
Washington University in St. Louis
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. WUSTL scientist wins prestigious Presidential Early Career Award
2. 3 WUSTL faculty named AAAS Fellows
3. WUSTLs Living Learning Center shares the worlds first full Living Building certification
4. UofL researcher awarded $2.6 million NIH grant renewal
5. Einstein College of Medicine given $6.7 million to study congenital heart defect genetics
6. UCSB awarded $15 million by Dow to establish collaborative institute for materials research and education
7. UMass Amherst wins major grant to host $7.5 million Northeast Climate Science Center
8. Lab receives $3 million for BioAMS instrument
9. Lithium-sulfur battery research receives $5 million from DOE
10. A living species of aquatic beetle found in 20-million-year-old sediments
11. A new species of fossil silky lacewing insects that lived more than 120 million years ago
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
WUSTL wins $ 2.2 million US Department of Energy grant to build a fuel producing bacterium
(Date:7/25/2014)... New research at the University of Adelaide has opened the ... resistance to powdery mildew. , In Australia, annual barley production ... year. Powdery mildew is one of the most important diseases ... team have discovered the composition of special growths on the ... the fungus into the leaf. , The research, by the ...
(Date:7/25/2014)... the age girls reach puberty is influenced by ,imprinted genes,a ... contributes the gene. This is the first evidence that ... and details of this study were published today in the ... known as menarche, is a marker for the timing of ... of menses varies between girls, is an inherited trait, and ...
(Date:7/25/2014)... Florida , July 25, 2014 ... more consumers are turning to digital technology for online ... (OTCBB: NXTD), Google Inc. (NASDAQ: GOOG ), ... (NYSE: V ), Apple Inc. (NASDAQ: ... NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company ...
Breaking Biology News(10 mins):New hope for powdery mildew resistant barley 2Could age of first period influence development of diseases in older women? 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 3Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 4Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 5Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 6
... cleaning your mouth, plaque begins forming before your brush even ... Yiping W. Han, a professor of periodontics at Case Western ... bacterium that inhabits the mouth, Fusobacterium nucleatum, She,s ... teeth and gums but enables disease and infection to spread ...
... Indiana University scientists have found chemical flame retardants in the ... higher than in humans, but lower than levels found in ... Retardants in the Serum of Pet Dogs and in their ... & Technology . Authors are Marta Venier, an assistant research ...
... , America is often referred to as the land of ... his "university of opportunity." NJIT gave him the opportunity, ... PhD, a distinguished professor in the department of physics. Naqvi ... a junior, his research recently helped him win a Goldwater ...
Cached Biology News:Mouth as the gateway to your body 2Study finds flame retardants at high levels in pet dogs 2Third brother wins gold at NJIT 2
(Date:7/24/2014)... 2014 -- Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") announced ... control Phase 3 study of Zerenex (ferric citrate), the ... treatment of hyperphosphatemia in patients with end-stage renal disease ... iRon delivery with FErric CiTrate in EsrD) was published ... Society of Nephrology ( JASN ). ...
(Date:7/24/2014)... Calif. , July 24, 2014  ECC West ... Denver, Colorado with University College Hospital (UCH) ... a development project to finance, design, construct, and operate ... Nigeria . Under the first of ... prepare scoping documents and funding applications. UCH Ibadan intends ...
(Date:7/24/2014)... natural and synthetic processes prefer to settle into ... energyit is within the realm of non-equilibrium conditions ... changes in energy and phases, such as temperature ... allow humans to regulate their body temperature, airplanes ... seismic activity. , But even though these ...
(Date:7/24/2014)... 2014  CorMedix Inc. (NYSE MKT: CRMD), a ... products for the prevention and treatment of cardiorenal ... on July 18, 2014 from the NYSE MKT ... CorMedix plan to regain compliance with continued listing ... NYSE-MKT is continuing the Company,s listing and has ...
Breaking Biology Technology:Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 2Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 3Zerenex (ferric citrate) long-term Phase 3 study results published in JASN 4ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2New approach to form non-equilibrium structures 2CorMedix, Inc. Granted Extension of NYSE-MKT Listing 2CorMedix, Inc. Granted Extension of NYSE-MKT Listing 3
... and building new microelectromechanical systems (MEMS) can benefit from ... of Standards and Technology (NIST) to measure a key ... determines the Youngs modulus of thin films not only ... integrated circuits. , Since 1727, scientists and engineers have ...
... SAN FRANCISCO, Jan. 9 Burrill Merchant Banking ... on its recently-completed,commercial partnering of bilastine with the ... Faes has licensed bilastine rights in Europe,and other ... allergic,rhinitis., Bilastine is a new highly selective ...
... PAREXEL International,Corporation (Nasdaq: PRXL ), a leading ... Holdener, M.D., formerly Head,of Global Pharmaceutical Development at ... Board of Directors., Dr. Holdener was recently ... The biotechnology Company develops new therapeutic,agents in the ...
Cached Biology Technology:NIST develops test method for key micromechanical property 2Burrill Merchant Banking Advises Faes Farma on Bilastine Licensing Agreement 2PAREXEL Names Biopharmaceutical Industry Executive Eduard E. Holdener to Board of Directors 2PAREXEL Names Biopharmaceutical Industry Executive Eduard E. Holdener to Board of Directors 3PAREXEL Names Biopharmaceutical Industry Executive Eduard E. Holdener to Board of Directors 4
Improves spot morphology and DNA binding to the slide resulting in increased hybridization signal. ID Clarifier: Optimized spotting solution for use with SigmaScreen APS Coated Slides for Microarrays...
... microarray slide processing offering reproducibility, reliability ... to miniaturization, automation and massive parallel ... tool with many applications in both ... range from gene expression profiling, gene ...
... This reagent is formulated specifically for ... consistently high levels of activity for both ... storage at final dilution. This product ... stability providing the customer a longer shelf ...
... kits for arraying proteins of interest ... lab equipment. DiscoverLight Protein Array Kits ... protein, cell lysate or antibody in ... include specially designed nitrocellulose membranes with ...
Biology Products: