Navigation Links
WSU researchers find way to make cancer cells more mortal
Date:7/16/2010

SPOKANE, Wash.Washington State University researchers have discovered a way to help cancer cells age and die, creating a promising avenue for slowing and even stopping the growth of tumors.

"Hopefully, we can make cancer cells die like normal cells," says Weihang Chai, an assistant professor in the WSU School of Molecular Biosciences and WWAMI medical education program in Spokane. "Basically, you make the cancer cell go from immortal to mortal."

Normal cells lose a little bit of their DNA every time they reproduce as the molecule's strands lose part of their protective tips, called telomeres. Eventually, the telomeres become too short, signaling to the cell to stop replicating and growing.

But cancer cells have a mechanism to keep their DNA strands from shortening, giving them a near eternal life. This is because the enzyme telomerase extends one strand of the cancer cell's DNA while other proteins help extend the second strand.

Chai and her colleagues, writing in the current issue of The EMBO Journal, say they have found a regulatory protein that controls the production of that second strand. They have also found a protein required to synthesize it.

If that second strand of DNA cannot be lengthened, says Chai, it behaves like a normal cell and dies a normal death. She says her team will now focus on developing a strategy to block the regulatory protein's function.


'/>"/>

Contact: Robert Strenge
rstrenge@wsu.edu
509-335-3583
Washington State University
Source:Eurekalert

Page: 1

Related biology news :

1. International AIDS Society and partners recognize outstanding researchers from around the world at AIDS 2010
2. Montana State researchers say Triceratops, Torsaurus were same dinosaur at different stages
3. CWRU dental researchers discover human beta defensins-3 ignite in oral cancer growth
4. In the ring: Researchers fighting bacterial infections zero in on microorganisms soft spots
5. Researchers use nanoparticles to shrink tumors in mice
6. Flemish researchers provide the first experimental evidence of dynamic allostery in protein regulation
7. Researchers apply computing power to crack egg shell problem
8. Mount Sinai researchers discover new way diseases develop
9. Researchers develop drug delivery system using nanoparticles triggered by electromagnetic field
10. MSU researchers awarded $9.1 million grant to battle malaria in Malawi
11. Researchers calculate the cost of CO2 emissions, call for carbon tax
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced ... India 2015-2019" report to their offering. ... market is the adoption of multimodal biometric systems. ... of an individual for verification and identification purposes. ...
(Date:12/10/2014)... 2014 You,ve been here before: you desperately need ... your password, site key or the answer to your secret ... teacher? Today, Hoyos Labs , a ... will finally put an end to the frustration that comes ... . 1U leverages a user,s smartphone to acquire his or ...
(Date:12/10/2014)... , Dec. 9, 2014 CIE San ... catalyst that provides the connective tissue that enhances care ... them to easily share client-level information; earned a second ... expand to organizations serving seniors aging in community and; ... partner on December 11 th 4-6p. ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... trillions of cells, all derived from a single cell, or zygote, ... single cell contains all the genetic information needed to develop into ... new cell as it divides into the many diverse types of ... If each cell is genetically identical, however, how does ...
... make sure their children drink milk and eat other calcium-rich foods ... make sure their kids eat salmon, almonds and other foods high ... in bone health, according to a study to be presented Sunday, ... Washington, DC. "Lots of nutrients are key for children ...
... and/or improve the quality of life for many cancer patients. ... inducing damage to DNA. The public has an opportunity ... used anticancer drugs and how laboratory research may lead to ... Yinsheng Wang , a professor of chemistry at ...
Cached Biology News:Divide and define: Clues to understanding how stem cells produce different kinds of cells 2Divide and define: Clues to understanding how stem cells produce different kinds of cells 3Magnesium may be as important to kids' bone health as calcium 2How do anticancer drugs work? 2How do anticancer drugs work? 3
(Date:12/19/2014)... The empty capsules market is experiencing growth ... technological innovations in the empty capsules market. The ... growth of the empty capsules market. , Get ... of Report , The report will enrich both ... to gauge the pulse of the market which ...
(Date:12/19/2014)... , Dec. 18, 2014 Relmada Therapeutics, ... for the treatment of chronic pain, announced the results ... "This was a transformational year in Relmada,s ... future for our company," said Sergio Traversa , ... we have executed on key financial, human resource and ...
(Date:12/17/2014)... BASKING RIDGE, N.J. (PRWEB) December 17, 2014 ... Ipsen (Euronext: IPN; ADR: IPSEY), ... 120 mg (referred to as Somatuline®) was approved ... for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) ... differentiated, locally advanced or metastatic disease to improve ...
(Date:12/17/2014)... December 17, 2014 Audacity, a leading ... and member of the Huntsworth Health Group, is proud ... executive team. In her role, Gonzales will serve as ... are incredibly honored to welcome a talent of Jamie’s ... CEO, Gaëtan Fraikin. “She is a proven healthcare innovation ...
Breaking Biology Technology:Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 8Audacity Welcomes Healthcare Communications Expert Jamie Gonzales as Senior Vice President of Client Services 2
... As ... accurately forecast, plan and respond to ever-changing market demands, ManufacturingOne meets the needs of ... ... a growing customer base in the high-tech manufacturing segment, YASH Technologies, a leading ...
... ... ... -- invivodata inc. , the industry leader in patient reported outcomes (PRO) solutions ... PRO Consulting , today announced a limited time, complimentary PRO Gap Analysis service to ...
... ... The International Marketplace. , ... (PRWEB) March 24, 2010 -- Sterlitech Corporation, one of the world’s leading producers ... prestigious Faces of Trade® Award presented by the US Chamber of Commerce. , ...
Cached Biology Technology:YASH Technologies™ Launches ManufacturingOne, a Qualified SAP Business All-in-One Partner Solution for the High-tech Manufacturing Industry 2YASH Technologies™ Launches ManufacturingOne, a Qualified SAP Business All-in-One Partner Solution for the High-tech Manufacturing Industry 3YASH Technologies™ Launches ManufacturingOne, a Qualified SAP Business All-in-One Partner Solution for the High-tech Manufacturing Industry 4invivodata Offers Complimentary PRO Gap Analysis 2invivodata Offers Complimentary PRO Gap Analysis 3US Chamber Of Commerce Honors Sterlitech Corporation 2
... a cytochrome P450 (CYP450) metabolite postulated to ... and cerebral vasculature. In rat cerebral microvessels, ... autoregulatory vasoconstriction. 20-HETE is excreted mainly as ... 20-HETE (20-40 pg/ml in human urine) is ...
Contact us for more information...
Rabbit polyclonal to Quinaldic Acid ( Abpromise for all tested applications). Antigen: Synthetic peptide Quinaldic Acid conjugated to a protein carrier....
... kinase (JNK) is one of the several ... been used as a sensitive reporter for ... a 1000-fold increase in sensitivity in comparison ... Firefly luciferase catalyzes the oxidative carboxylation of ...
Biology Products: