Navigation Links
WPI team scales-up production of biopolymer microthreads
Date:4/30/2012

the body. It's the building block for skin and connective tissues such as tendons, ligaments, muscle, and cartilage. So Pins and his lab team theorized that thin threads of collagen would be well-tolerated by the body. As the work continued, the team also began making microthreads from fibrin, which is the main protein in blood clots; since clotting is an early response to injury Pins believed that fibrin threads could become useful scaffolds for wound-healing applications.

Initially, Pins and his lab team made each thread by hand, using a large syringe to push out a bead of collagen or fibrin, draw it into a bath of solution, then lift it out by hand to dry suspended over the edges of a cardboard box. "I always looked for the student with the steadiest hands to draw out the threads," Pins said, noting that it was difficult to get the threads to be consistent in diameter and length.

While the hand-drawn method demonstrated the promise of the concept, Pins challenged several of his undergraduate students to develop an automated system for making the threads in a consistent manner. Two Major Qualifying Project (MQP) teams tackled the challenge over the course of two years. Working collaboratively with WPI faculty members in mechanical engineering and robotics engineering, they developed a working bench-scale prototype that automated most of the thread production process. "The prototype worked well, and produced more consistent threads," Pins noted.

By early 2010, interest in the microthreads had expanded beyond Pins's lab, as colleagues at WPI saw opportunities to use them in their own areas of research. With demand for new threads growing, Paul Vasiliadis, a member of one of the MQP teams, began planning to take microthread production to the next level. After earning his bachelor's degree in 2010, Vasiliadis joined Gaudette's lab as a graduate student and became the lead developer of the production-scale extrusion system now bei
'/>"/>

Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. ID Solutions Achieves Full-Production Delivery and Payment for Fingerprint Processing Software for TWIC
2. Mandate for biofuels production requires science-based policy and global perspective
3. Oklahoma researchers support biodiversity in biofuels production
4. New $11 million center to speed production of new compounds for drug discovery
5. Biosynthetics production with detours
6. Bacteria manage perfume oil production from grass
7. New hybrid plants could prompt more prodigious pepper production in Southwest
8. Scripps research scientists identify compounds for stem-cell production from adult cells
9. December 2008 highlights from Biology of Reproduction
10. Novel bioreactor enhances interleukin-12 production in genetically modified tobacco plants
11. Attitudes towards assisted reproduction and preimplantation genetic diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
WPI team scales-up production of biopolymer microthreads
(Date:8/22/2014)... . , Thanks ... in a way so as to align themselves symmetrically, ... University researchers are planning on looking into how PCFs ... being published today in the scientific journal Nature ... Everyone knows that at least from having boiled ...
(Date:8/22/2014)... reductase (DHCR24) is a multifunctional enzyme ... and has neuroprotective and cholesterol-synthesizing activities. ... caused by amyloid β deposition. Dr. ... University in China constructed two recombinant ... DHCR24 expression specifically in neuronal cells. ...
(Date:8/21/2014)... including researchers from the University of Georgia recently published the ... journal Science . Their discovery paves the way for ... farming and industry. , Canola is grown across much ... is increasingly cultivated in Georgia. Canola oil used for cooking ... and rich supply of omega-3 fatty acids, but the plant ...
Breaking Biology News(10 mins):Proteins: New class of materials discovered 2Canola genome sequence reveals evolutionary 'love triangle' 2
... at Duke's Pratt School of Engineering have imaged the ... showed that the probes could give surgeons a better ... performed through tiny "keyhole" incisions. , If the probes ... to more precise and safer endoscopic surgeries, said the ...
... soon be offered the opportunity to have their daughters ... major cause of cervical cancer, the 4th International Conference ... (Thursday 30 March). , Professor Henry Kitchener told the ... progress in developing vaccines against the human papillomavirus (HPV) ...
... ends of bones where they meet in a joint) ... lead to degenerative disease. Treatments and experimental approaches to ... currently there is no method to fully restore this ... of therapeutic proteins to the injured site is a ...
Cached Biology News:3D ultrasound device poised to advance minimally invasive surgery 23D ultrasound device poised to advance minimally invasive surgery 3Parents need to be educated about HPV vaccinations for daughters 2Parents need to be educated about HPV vaccinations for daughters 3Stem cells from muscles can repair cartilage 2Stem cells from muscles can repair cartilage 3
(Date:8/21/2014)... An international research team including DESY scientists has observed ... The team reports in the journal Science ... lattices inside the nanodroplets. It is the first time ... in larger samples of what is known as superfluid ... exceeded our best expectations," says Andrey Vilesov of the ...
(Date:8/21/2014)... The College of New Rochelle announced ... the Mid-Hudson Region to be designated as a START-UP ... from qualified “high-technology” businesses that align with the College’s ... have been selected for the START-UP NY program and ... stimulate economic development in New York by growing business ...
(Date:8/21/2014)... 21, 2014  Four-dimensional (4-D) printing develops materials ... external stimuli such as changes in temperature. This ... effect in multiple industries.  In the near future, ... printing objects ranging from human organs to parts ... Logo - http://photos.prnewswire.com/prnh/20140820/138289 ...
(Date:8/21/2014)... On Wednesday of last week RENU 28, ... Signaling molecules, became available for purchase in Australia and New ... that RENU 28 works is, if you think about the ... rate of cellular renewal within your body. If you think ... rate of cellular renewal. What RENU 28 does is it ...
Breaking Biology Technology:Scientists observe quantum vortices in cold helium droplets 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 4RENU 28 Skin Care Now Available in Australia and New Zealand 2
... VIEW, Calif., Feb. 27 Alexza,Pharmaceuticals, Inc. (Nasdaq: ... Simms,has joined the company as Senior Vice President, ... Vice President,Manufacturing Operations at Nektar Therapeutics. Mr. Simms ... Pharmaceuticals and Vice President,Device Development and Manufacturing from ...
... Calif., Feb. 27 /Xinhua-PRNewswire-FirstCall/ --,Kiwa Bio-Tech Products Group ... being considered as a supplier of bio-fertilizers,for the ... and hotels,during the 2008 Olympics. Kiwa also announced ... of the Company, would participate in an interview ...
... 27 DARA BioSciences(TM),(Nasdaq: DARA ) announced today ... of Directors. Mr. Cochrane was appointed to fill a ... Compensation Committees.,The appointment was effective February 21, 2008., ... Sr.,commented, "We are pleased that Haywood has joined us ...
Cached Biology Technology:Michael J. Simms Joins Alexza Pharmaceuticals as Senior Vice President, Operations and Manufacturing 2Michael J. Simms Joins Alexza Pharmaceuticals as Senior Vice President, Operations and Manufacturing 3Beijing 2008 Olympic Games Vegetable Supplier Considering Kiwa as a Supplier of Bio-Fertilizers & Kiwa Announces CEO Interview with WallSt.net 2Beijing 2008 Olympic Games Vegetable Supplier Considering Kiwa as a Supplier of Bio-Fertilizers & Kiwa Announces CEO Interview with WallSt.net 3DARA BioSciences, Inc. Announces Appointment of New Director to Board 2
...
... DNA Purification Kit is designed for isolating DNA ... The protocol can be completed in less than ... obtain larger amounts of DNA. The purified DNA ... and Southern blotting. The MasterPure Kit was designed ...
Caspase Activity Detector, SR-VAD-FMK Kit , 100 tests Consult technical datasheet for details....
HistoScan AP Universal Goat Kit...
Biology Products: