Navigation Links
WPI research shows how cranberry juice fights bacteria at the molecular level
Date:7/15/2010

WORCESTER, Mass. -- Revealing the science behind the homespun advice, a team of researchers at Worcester Polytechnic Institute (WPI) has identified and measured the molecular forces that enable cranberry juice to fight off urinary tract infections in people.

The data is reported in the paper "Direct adhesion force measurements between E. coli and human uroepithelial cells in cranberry juice cocktail," which was published on-line, ahead of print, by the journal Molecular Nutrition & Food Research. The research illuminates the basic mechanics of E.coli infections, which has implications for developing new antibiotic drugs and infection-resistant materials for invasive medical devices.

The research team led by Terri Camesano, professor of chemical engineering at WPI, focuses on the virulent form of E. coli bacteria that is the primary cause of most urinary tract infections. This strain of E. coli is covered with small hair-like projections known as fimbriae, which act like hooks and latch onto cells that line the urinary tract. When enough of the virulent E. coli adhere to cells in this way, they cause an infection. Previous work by Camesano has shown that exposure to cranberry juice causes the fimbriae on E. coli to curl up, reducing their ability to attach to urinary tract cells. In the new study, Camesano's team presents the first specific measurements of the mechanical forces involved in the attachment of the virulent E. coli to human urinary tract cells. The study also documents how the force of attachment is reduced in the presence of cranberry juice cocktail. "This is not a clinical studyit's a mechanical study that shows us the direct forces that can lead to infection," Camesano said.

To make measurements at the molecular level, Camesano's team developed a method to attach a single E. coli cell to the tip of a probe mounted on a device called an atomic force micro
'/>"/>

Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. LSU researcher looks for new ways to keep a dirty situation clean
2. Grant to fund research into eradicating the leukemia stem cell
3. Montana State researchers say Triceratops, Torsaurus were same dinosaur at different stages
4. UCI receives prestigious federal research award to hasten medical advances
5. International AIDS Society announces inaugural recipients of innovative HIV research awards
6. New research on rapidly-disappearing ancient plant offers hope for species recovery
7. CWRU dental researchers discover human beta defensins-3 ignite in oral cancer growth
8. In the ring: Researchers fighting bacterial infections zero in on microorganisms soft spots
9. The Samuel Waxman Cancer Research Foundation awards $1.54 million in research grants for 2010-2011
10. InQ Biosciences Introduces First Fully Integrated Cell Research System
11. Penn State to lead new international Center Of Excellence for malaria research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
WPI research shows how cranberry juice fights bacteria at the molecular level
(Date:7/11/2014)... There is evidence that under the normal ... and development, maintain neuronal environment, and exhibit ... and neurodegenerative disease. Previous studies have found ... cells after chemical induction have reduced viability, ... application. Prof. Xiaodong Yuan, Kailuan General Hospital, ...
(Date:7/11/2014)... Research and Markets has announced the addition ... Analysis Size Share Growth Trends and Forecast to 2019" ... http://photos.prnewswire.com/prnh/20130307/600769 The rising number of ... high level security in both private and public sector. ... and passwords, tokens etc. are vulnerable to attacks. Biometrics ...
(Date:7/11/2014)... of all vertebrates, information is transmitted through synapses, ... signal to be passed from one brain cell ... abundant type of synapse, can be either excitatory ... memory, perception and cognition, and the balance between ... For instance, every time we learn something, ...
Breaking Biology News(10 mins):International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2Blame it on the astrocytes 2
... HILO, HawaiiIn collaboration with Stanford University and ... Service Pacific Southwest Research Station,s Institute of Pacific ... developing "hybrid ecosystems"a mix of native and non-native ... in tropical forests. The research team, comprised ...
... parrots and iguanas may seem inoffensive at first glance when ... escape and become invasive species. This has been confirmed by ... 63 Spanish zoos. Birds are the animals most likely to ... (non-indigenous) species, they could become an entry channel for these ...
... -- Specialized white blood cells called T cells and ... and eliminate "non-self" substances such as viruses and bacteria. ... immunoreceptors on the cell surface bind to specific regions on, ... pathways inside the T cells and B cells that control ...
Cached Biology News:US Forest Service and 2 universities team up to develop new ecosystems for Hawaiian forests 275 percent of Spanish zoos at risk of exotic animals escaping 275 percent of Spanish zoos at risk of exotic animals escaping 3
(Date:7/10/2014)... 15, 2014 -- According to the International Atomic ... security comes from terrorists acquiring sufficient quantities of ... a crude nuclear explosive device. The IAEA also ... have involved gram-level quantities, which can be challenging ... to a new study appearing this week in ...
(Date:7/10/2014)... basis of psychiatric disorders has been extremely challenging because ... but are insufficient to cause disease. Now investigators reporting ... journal Cell Stem Cell describe a strategy ... interact with other risk factors or environmental exposures to ... pinpoints a genetic variant that may predispose individuals to ...
(Date:7/10/2014)... shelled out for crude 3-D glasses, polarized glasses, ... These basic devices, used to trick the brain ... be rendered obsolete with the introduction of new ... , TAU doctoral students Yuval Yifat, Michal Eitan, ... based on nanoantennas that could be used for ...
(Date:1/15/2014)... "The interface is the device," Nobel laureate Herbert ... to be found at the junctures where layers ... of nanotechnology, the interfaces between layers of metal ... such high-tech favorites as spintronics, high-temperature superconductors, ferroelectrics ...
Breaking Biology Technology:Sensitive detection method may help impede illicit nuclear trafficking 2New strategy could uncover genes at the root of psychiatric illnesses 2Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3A deeper look at interfaces 2
... ANGELES, Feb. 18 The Board of Directors wishes to ... 2009 it resolved to file a Form 15 with effect ... the approval of stockholders but in the interests of keeping ... Release.The effect of this filing is to release the company ...
... SAN DIEGO, Feb. 18 Zogenix, Inc. ("Zogenix"), a ... Drug,Administration (FDA) has provided a target date of July ... for Sumavel DosePro (sumatriptan,injection) needle-free delivery system. Zogenix ... treatment of migraine attacks with or without,aura, and the ...
... Inc. (the "Company") (Nasdaq: PDGI ), a ... biotechnology, generic drug and medical device companies, today announced ... Brazil to further enhance its Latin American presence.PharmaNet has ... 2002 with a network of field-based staff in Brazil, ...
Cached Biology Technology:EESTECH Inc - Release From SEC Filing 2EESTECH Inc - Release From SEC Filing 3EESTECH Inc - Release From SEC Filing 4Zogenix Reports FDA Provides New PDUFA Date for Sumavel(TM) DosePro(TM) 2PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 2PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 3PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 4PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 5
Recombinant Equine IL-6...
... two highly efficient methods of identifying recombinant ... By using the large-scale screen method in ... is to transfer partial colonies of E. ... into the solutions provided by the kits ...
... Fernandez and G. Butcher (1998). • The ... much research in the immunology area. There ... MHC proteins and in their function as ... faced with the prospect of tackling biochemical ...
actin from rabbit muscle Cell Biology Cytoskeletal Probes Actin and Actin Probes...
Biology Products: