Navigation Links
WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
Date:3/24/2010

WORCESTER, Mass. A Worcester Polytechnic Institute (WPI) research team has received a four-year, $1.4 million award from the National Institutes of Health (NIH) to continue a groundbreaking study of arterial plaque. This research could lead to tools that will enable physicians to predict the likelihood of plaque rupture, which is responsible for most heart attacks and strokes. Led by Dalin Tang, PhD, professor of mathematical sciences and biomedical engineering at WPI, the team is collaborating with researchers at Washington University in St. Louis and the University of Washington in Seattle on the research, which combines sophisticated computer modeling with an array of diagnostic technologies to more accurately chart the development of atherosclerotic plaque (fatty deposits) in the coronary arteries.

Arterial plaques are complex structures made up of cholesterol and other fats, calcium, fibrin (a protein that helps blood clot), and other materials. When they reach an advanced stage, plaques may develop a thin, membranous or fibrous cap. When this is torn open, it releases the contents of the plaque into the bloodstream. Plaque rupture causes some 60 percent of sudden, unexpected heart attacks. While the link between plaque build-up and cardiovascular disease has long been recognized, the factors that cause plaques to form, grow and rupture have been less clearly understood.

Better understanding the evolution of arterial plaque is important, Tang says, given the central role it plays in cardiovascular disease. As plaque deposits grow they cause a narrowing of arteries (called stenosis), which diminishes the amount of oxygen and nutrients blood can carry to the body and puts increasing stress on the heart. When plaques rupture, a blood clot (thrombosis) typically forms at the site and may block the artery. Such a blockage in a coronary artery leading to the heart is called a myocardial infarction or a heart attack. A similar blockage of t
'/>"/>

Contact: Michael Dorsey
mwdorsey@wpi.edu
508-831-5609
Worcester Polytechnic Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Lombardi receives $7.5 million grant for Breast Cancer Center for Cancer Systems Biology
2. WPI receives $1.2 million NIST award for pioneering study of wireless body area networks
3. Springer editorial board member receives Humboldt Research Award
4. Clemson researcher receives grant to study engineering enrollment of women, minorities
5. NJIT electrical engineer Yanchao Zhang receives NSF CAREER Award
6. Dr. Harmit Malik receives Vilcek Prize for creative promise in biomedical science
7. Oberthur Technologies Receives Product Innovation Award
8. Caltech receives more than $33 million from American Recovery and Reinvestment Act
9. Tulane receives $15 million NIH contract to develop vaccine and treatment for deadly fever
10. Carnegie Mellons John Kitchin receives early career award
11. Jedi Mind Receives Vast Media Coverage at CES in Las Vegas
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
(Date:4/23/2014)... allergies and other chronic inflammatory disorders among people of ... their reduced exposure to the microbes that thrive in ... The article, published in the journal Clinical & ... centers who have less access to green spaces may ... caused by immune system dysfunction. , When our immune ...
(Date:4/23/2014)... This news release is available in French and ... woman? Male or female? In humans and other mammals, the difference ... Y chromosome. It is present only in males, where the two ... chromosomes. Thus, the Y is ultimately responsible for all the morphological ... not always been the case. A very long time ago, the ...
(Date:4/23/2014)... ripping open a dinner roll, a fuel cell catalyst ... hydrogen molecule. Now researchers have captured a view of ... its hydrogen feast. The view confirms previous hypotheses and ... better for alternative energy uses. , This study is ... hydrogen halves end up in the structure of a ...
Breaking Biology News(10 mins):Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3Male or female? 2Male or female? 3Halving hydrogen 2Halving hydrogen 3Halving hydrogen 4
... in Europe and United States are markedly underestimating the ... to prevent dangerous climate change because they work in ... from The University of Manchester, discovered that the lack ... has resulted in significant differences over who is responsible ...
... An international research team has identified a common gene ... atrial fibrillation. In their report in the journal ... that variations affecting a protein that may help control the ... is called lone atrial fibrillation (AF), a type seen in ...
... Blacksburg, Va. -- Math-based computer models are a powerful ... John Tyson, professor of biology at Virginia Tech, is ... and make decisions. "Cells receive information in the ... or radiation damage, for instance," Tyson said. "On the ...
Cached Biology News:Governments 'misjudging' scale of CO2 emissions 2Common gene variant may increase risk for a type of cardiac arrhythmia 2Biologists use mathematics to advance our understanding of health and disease 2Biologists use mathematics to advance our understanding of health and disease 3
(Date:1/14/2014)... January 14, 2014 EquitiesIQ, a leading ... (OTCQB: ALQA). Alliqua is an emerging biomedical company acquiring, ... wound care market. , Free report download: http://equitiesiq.com/reports/alliqua/ ... a seasoned management team and Board, which launched the ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility ... of Product Strategy. In this role, Michelle will work with ... guide in the development of iLab products. Her main goal ... benefit to the scientific community by offering the most advanced, ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Global ... developing innovative information technology solutions for patients, physicians, ... care stakeholders, announced today the signing of a ... Food and Drug Administration (FDA). This initiative ...
(Date:1/14/2014)... January 14, 2014 Kerr Corporation, a leading ... and additional how-to information about dual arch impressions on its ... Dual Arch Impressions,” the blog entry serves up a list ... houses a step-by-step demonstration by Dr. David Little as he ...
Breaking Biology Technology:EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... equity stake in Zenotech Laboratories to 45%, GURGAON, ... Laboratories Limited (Zenotech) today announced the,signing of Definitive Agreements, ... its current 7% to 45% at a price of ... involves: (a) Purchase of shares from the existing ...
... Monday, October 8, at 2:15 ... p.m. ... Sciences Holdings, Inc. (Nasdaq: ADLS ), a biopharmaceutical,company engaged in the ... respiratory diseases and,cancer, is scheduled to present at the Natixis Bleichroeder Hidden ...
... 3 /PRNewswire-FirstCall/ - Biomira Inc. (Nasdaq: BIOM ... President and Chief,Executive Officer, is scheduled to present ... 2:45pm PDT/5:45pm EDT on Wednesday, October 10. ... and can be accessed at: http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=BIOM&item_id=1 ...
Cached Biology Technology:Ranbaxy to Consolidate Position in Biopharmaceuticals and Speciality Injectables Including Oncology 2Ranbaxy to Consolidate Position in Biopharmaceuticals and Speciality Injectables Including Oncology 3Advanced Life Sciences to Present at Natixis Bleichroeder Hidden Gems Conference 2
Rabbit polyclonal to Tryptophanyl tRNA synthetase ( Abpromise for all tested applications). Antigen: Recombinant full length protein (Human): Tryptophanyl tRNA synthetase Entrez Gene ID: 745...
Goat polyclonal to FBXO2 ( Abpromise for all tested applications). entrezGeneID: 26232 SwissProtID: Q9UK22...
Rat monoclonal to UGGT ( Abpromise for all tested applications)....
... (Ser843) Immunogen: ... encompassing the human, mouse, and rat ... Number: NM_153831 ... by immunoblot. ...
Biology Products: