Navigation Links
WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
Date:3/24/2010

WORCESTER, Mass. A Worcester Polytechnic Institute (WPI) research team has received a four-year, $1.4 million award from the National Institutes of Health (NIH) to continue a groundbreaking study of arterial plaque. This research could lead to tools that will enable physicians to predict the likelihood of plaque rupture, which is responsible for most heart attacks and strokes. Led by Dalin Tang, PhD, professor of mathematical sciences and biomedical engineering at WPI, the team is collaborating with researchers at Washington University in St. Louis and the University of Washington in Seattle on the research, which combines sophisticated computer modeling with an array of diagnostic technologies to more accurately chart the development of atherosclerotic plaque (fatty deposits) in the coronary arteries.

Arterial plaques are complex structures made up of cholesterol and other fats, calcium, fibrin (a protein that helps blood clot), and other materials. When they reach an advanced stage, plaques may develop a thin, membranous or fibrous cap. When this is torn open, it releases the contents of the plaque into the bloodstream. Plaque rupture causes some 60 percent of sudden, unexpected heart attacks. While the link between plaque build-up and cardiovascular disease has long been recognized, the factors that cause plaques to form, grow and rupture have been less clearly understood.

Better understanding the evolution of arterial plaque is important, Tang says, given the central role it plays in cardiovascular disease. As plaque deposits grow they cause a narrowing of arteries (called stenosis), which diminishes the amount of oxygen and nutrients blood can carry to the body and puts increasing stress on the heart. When plaques rupture, a blood clot (thrombosis) typically forms at the site and may block the artery. Such a blockage in a coronary artery leading to the heart is called a myocardial infarction or a heart attack. A similar blockage of t
'/>"/>

Contact: Michael Dorsey
mwdorsey@wpi.edu
508-831-5609
Worcester Polytechnic Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Lombardi receives $7.5 million grant for Breast Cancer Center for Cancer Systems Biology
2. WPI receives $1.2 million NIST award for pioneering study of wireless body area networks
3. Springer editorial board member receives Humboldt Research Award
4. Clemson researcher receives grant to study engineering enrollment of women, minorities
5. NJIT electrical engineer Yanchao Zhang receives NSF CAREER Award
6. Dr. Harmit Malik receives Vilcek Prize for creative promise in biomedical science
7. Oberthur Technologies Receives Product Innovation Award
8. Caltech receives more than $33 million from American Recovery and Reinvestment Act
9. Tulane receives $15 million NIH contract to develop vaccine and treatment for deadly fever
10. Carnegie Mellons John Kitchin receives early career award
11. Jedi Mind Receives Vast Media Coverage at CES in Las Vegas
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
WPI receives $1.4 million from NIH for pioneering work on arterial plaque and cardiovascular disease
(Date:4/2/2015)... , April 2, 2015 ... Q1 2015 attributed to somewhat higher than 125 MSEK. ... the year-end report 2014 that revenues for Q1 2015 ... the company reported for Q4 2014. The operating result ... be negative. The complete interim report will as previously ...
(Date:3/31/2015)... , March 31, 2015   Guidepoint , ... launch of the Post-Surgical Pain Management TRACKER, part of ... tracking usage trends in the medical device and therapeutics ... to data including treatment volumes, market share, and adoption ... pain associated with joint surgery. The Post-Surgical ...
(Date:3/24/2015)... NexID Biometrics LLC, whose spoof-mitigation technology boosts protection ... beginning of shipments of version 2.0 of its industry ... in Potsdam, N.Y. , is making ... here today at the Walter E. Washington Convention Center. ... boosts the accuracy rate range to 96.5 to 99.5 ...
Breaking Biology News(10 mins):Fingerprint Cards Revises Revenues for Q1 2015 2Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2
... Organization (EMBO) and the Federation of European Biochemical ... Friedrich Miescher Institute for Biomedical Research in Basel, ... Women in Science Award. Professor Gasser has been ... stability and epigenetics and her commitment to mentoring ...
... (New York, NY) The Alfred P. Sloan ... outstanding U.S. and Canadian researchers as recipients of Sloan ... fellowships are given to early-career scientists and scholars whose ... next generation of scientific leaders. "Today,s Sloan Research ...
... DETROIT Technology to restore vision through the use ... a Wayne State University professor and scientific director of ... Eye Institute has attracted additional funding for therapy ... grant from their affiliate, National Neurovision Research Institute, to ...
Cached Biology News:Susan M. Gasser to receive the 2012 FEBS/EMBO Women in Science Award 2Sloan Research Fellowships awarded to 126 young scholars 2Wayne State-licensed technology receives grant from the Foundation Fighting Blindness 2
(Date:4/16/2015)... San Francisco, CA (PRWEB) April 16, 2015 ... is scheduled to report first quarter results on Thursday, ... the announcement, Cytokinetics’ senior management will host a conference ... and financial results and the company’s outlook for the ... and can be accessed from the homepage and in ...
(Date:4/16/2015)... 16, 2015 According to the ... an outside source was ranked first among the ... related to lifting, pushing, pulling, holding, carrying, or ... costs. The David Round Company takes statistics like ... working hard to develop and design equipment that ...
(Date:4/16/2015)... 16, 2015  RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX) ... joint venture with G-treeBNT (ReGenTree LLC) has retained ... trial for the orphan disorder, neurotrophic keratopathy (NK), ... eye syndrome (DES) in the U.S.  Both trials ... this year.  Each of these eye disorders was ...
(Date:4/16/2015)... Calif. , April 16, 2015  Scientists from ... "New Drugs on the Horizon," at the American Association ... Philadelphia, PA on Sunday, April 19, 2015 ... Ph.D., Cleave,s Director of Biology, will present new in ... a first-in-class, oral inhibitor of p97, a critical enzyme ...
Breaking Biology Technology:Cytokinetics to Announce First Quarter Results on April 30, 2015 2Cytokinetics to Announce First Quarter Results on April 30, 2015 3The David Round Company Helps Companies Meet OSHA Standards by Combining Safety, Ergonomics, and Productivity 2RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 2RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 3RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 4RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 5Cleave Biosciences to Participate in Special Session "New Drugs on the Horizon" at AACR Annual Meeting 2015 2Cleave Biosciences to Participate in Special Session "New Drugs on the Horizon" at AACR Annual Meeting 2015 3
... 30 Champions,Biotechnology, Inc. (OTC Bulletin Board: CSBR), ... platforms and tumor specific data to,enhance the value ... the fiscal year ended April 30, 2008. Full ... the Company,s Form 10-KSB available at, http://www.championsbiotechnology.com ., ...
... today announced that it has partnered with Green Mountain Energy Company ... total calculated carbon dioxide (CO2) emissions thereby enabling them to operate ... ... Mesa, CA (PRWEB) July 30, 2008 -- Alkemists Pharmaceuticals today announced ...
... announces the following Webcast:, What: Transgenomic Inc. ... Conference Call, When: Wednesday, August ... , How: Live over the Internet -- ... address above., Contact: Investor Relations, ...
Cached Biology Technology:Champions Biotechnology Reports Fiscal 2008 Full-Year Financial Results 2Champions Biotechnology Reports Fiscal 2008 Full-Year Financial Results 3Champions Biotechnology Reports Fiscal 2008 Full-Year Financial Results 4Alkemists Sets The Bar, Becoming a 'Green' Analytical Laboratory 2Alkemists Sets The Bar, Becoming a 'Green' Analytical Laboratory 3
Applications include ELISA, immunochemistry, and Western blotting. Working Concentrations: ELISA: 0.005-0.05 U/ml, immunohisto/cytochemistry: 0.25-0.5 U/ml, Western blot: 0.1-0.25 U/ml....
...
Recombinant Ovine IFN Tau. Active on sheep, cow, human and mouse cells. Activity: 5.7 x 10 7 u/mg...
... Thermo's Wellwash AC is the ... available, and is provided with liquid ... rinse bottles. The integrated orbital shaker ... guarantee excellent washing performance. The big ...
Biology Products: