Navigation Links
W.M. Keck Foundation grant funds reproductive science research
Date:7/29/2008

namely, the relationship of physiologically relevant metals to the events surrounding fertilization," said Woodruff. "The involvement of inorganic molecules in this process has not been examined, and the development of imaging technologies that are predicted to bring a new level of sensitivity and detection capability to this critical time in biology is exciting."

The team will use the Keck Foundation grant to purchase a custom-built scanning transmission electron microscope with multiple detectors for quantitative images of the inorganic elements in the mouse germ cells. No existing microscope can do this. Furthermore, the movement and flux of these ions will be tracked in live cells using confocal microscopy. New fluorescent "nanosensors" will be developed specifically for these studies.

The work lies at the interface of reproductive science, chemistry, biophysics and imaging technology. Also on the research team are Vinayak P. Dravid, professor of materials science and engineering at Northwestern and director of the University's NUANCE Center (Atomic and Nanoscale Characterization Experimental Center), and Jonathan Silverstein, M.D., associate professor of surgery and radiology at the University of Chicago Medical Center and associate director of the university's Computation Institute.

Dravid's expertise lies in advanced microscopy and analytical techniques; he will coordinate construction of the electron microscope and develop methods to use the equipment. Silverstein specializes in the application of computers and other technology to the analysis of vast biomedical databases; he will develop software to interpret the data collected using the microscope and will create 3-D images of the eggs showing amounts and distribution of the inorganic molecules.

The origin of the idea, that zinc in particular may play an important role in these signaling pathways, came from the research of graduate student Alison Kim, who is working w
'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. W.M. Keck Foundation announces 2008 class of Distinguished Young Scholars in Medical Research
2. Michael J. Fox Foundation awards $2.4M for validation of therapeutic targets for Parkinsons
3. Glenn Foundation for Medical Research commits $5 million to study aging
4. BBVA Foundation Awards for Biodiversity Conservation
5. The Parkinsons Disease Foundation awards $950,000 in seed grants
6. The AGA Foundation invests in gastroenterologys future
7. European Science Foundation aims to strengthen regenerative medicine
8. National Science Foundation funds research addressing enduring questions of life
9. Spradling receives Gruber Foundation Genetics Prize for new genetic techniques
10. BBVA Foundation international study on attitudes to stem cell research
11. Landon Foundation-AACR INNOVATOR Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... are implicated in many serious conditions such as heart ... target for drug therapies. Unfortunately, there is still much ... research provides fresh and unexpected insight into the structure ... - β-subunit molecules - which are responsible for ,fine-tuning, ... in the most recent edition of the Journal ...
(Date:4/17/2014)... is the process whereby the genetic information of ... as proteins, which have numerous different functions in ... important intermediary during gene expression, by relating the ... involved in manufacturing proteins. , By examining ... present in an organism at a given time, ...
(Date:4/17/2014)... by the Australian National University (ANU), have developed ... deep-sea temperature variability over the past 5.3 million ... the climate surrounding ice ages over the past ... relationship between carbon dioxide levels, global temperatures and ... of Southampton (UoS) and the National Oceanography Centre ...
Breaking Biology News(10 mins):Structure of sodium channels different than previously believed 2Rapid and accurate mRNA detection in plant tissues 2Ancient sea-levels give new clues on ice ages 2
... to caution about the many things that could go ... contain a Southeast Asian outbreak of avian influenza in ... vaccine. , Using a computer model to simulate an ... have shown how a combination of strategies, including targeted ...
... and not the last ice age are the likely culprits ... American great mammals such as mammoths, mastodons and saber-toothed tigers, ... first arrival of humans or the warm-up of the American ... responsible for the demise of prehistoric sloths has puzzled scientists ...
... Canada in 2004 emitted about as much carbon monoxide ... during the same time period, according to new research ... fires also increased atmospheric concentrations of ground-level ozone across ... which indicates the extent to which wildfires contribute to ...
Cached Biology News:Preventing a pandemic: Study suggests strategies for containing a flu outbreak 2Preventing a pandemic: Study suggests strategies for containing a flu outbreak 3Study shows big game hunters, not climate change, killed off sloths 2Study shows big game hunters, not climate change, killed off sloths 3NCAR analysis shows widespread pollution from 2004 wildfires 2
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 More than ... and about 1 in 3 seniors will die with ... ). These jaw-dropping figures have shocked many Americans into ... hopefully, help prevent these tragic age-related cognitive disorders. Jonathan ...
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how ... latent viruses is the Epstein Barr Virus (EBV), and one ... is a chronic inflammatory disease that destroys the body’s joints. ... patients have high concentrations of EBV DNA in their bodies ...
(Date:1/15/2014)... January 15, 2014 2013 was a ... Brain State Technologies®. They saw continued independent research led ... who were awarded a $1 million grant from the ... “Brain and Behavior” a peer reviewed journal, Amy Grant ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3
... , SAN DIEGO, July 30 Cardium ... to develop a DNA-based orthobiologics product portfolio based on research ... focus on non-union bone fractures for medically-compromised patients, and spinal ... a rapidly growing segment of the orthopedics market and represents ...
... , NEW YORK, July 30 Stemline Therapeutics, ... of oncology compounds directed to cancer stem cell targets, today ... invited to present at the New Frontiers in Cancer Drug ... Development Week in Boston, MA. Dr. Bergstein,s presentation, entitled ...
... July 30 /PRNewswire-Asia-FirstCall/ -- Lotus Pharmaceuticals, Inc.,(OTC Bulletin ... developer and,producer of prescriptions drugs and licensed national ... China, today reported it received notice,of patent pending ... People,s,Republic of China for its innovative patent application ...
Cached Biology Technology:Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 2Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 3Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 4Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 5Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 6Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 7Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 8Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 9Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors 10Stemline Therapeutics CEO to Present at IBC's New Frontiers in Cancer Drug Development Conference 2Lotus Pharmaceuticals, Inc. Announces Patent Pending Gliclazide-Controlled Release Tablets 2Lotus Pharmaceuticals, Inc. Announces Patent Pending Gliclazide-Controlled Release Tablets 3
... in a regulated environment, Pipette Tracker ... software that automates gravimetric pipette calibration ... that meets todays regulatory compliance requirements. ... solution that includes a full security ...
... AAIPharmas Routine Testing Laboratory (RTL) ... developed over 25 years. ,,Microbial method ... used to monitor the conditions of ... quality for manufactured products,,We offer a ...
... Research Scale (gram quantities of IgY) , ... Prepare your Antigen), we segregate the appropriate number ... After 3 such eggs are collected (usually over ... injection series. This involves a total of four ...
... cDNA Library Panels were designed for full-length ... of PCRs to identify the desired cDNA ... in a 96-well "Master Plate," where each ... Having identified the positive well(s) by gel ...
Biology Products: