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Vitamin E trials 'fatally flawed'
Date:9/23/2007

i said. We need to select people for trials properly, make sure they are taking the right form of the vitamin, at the right levels and at the right time, and then verify the metabolic results with laboratory testing.

Only when we do these studies right will we answer questions about the value of vitamin E in addressing cardiovascular disease, he said. So far weve been flying blind.

A parallel, Frei said, would be presuming to test the value of a statin drug, which lowers cholesterol, without ever measuring cholesterol levels in the test subjects, neither at the beginning nor at the end of the study. Such trials would be ridiculed in the science community.

So far, thats the way vitamin E has been studied.

The use and intake of vitamins, experts say, has traditionally been thought of in terms of overt deficiency for example, not enough vitamin C causes scurvy. Much less research has been done on the levels that can help create optimum health. The issue is of special importance with modern populations that have very different diets, activity levels and increased lifespan, and are dying from much different causes predominantly heart disease and cancer than people of past generations.


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Contact: Balz Frei
balz.frei@oregonstate.edu
541-737-5078
Oregon State University
Source:Eurekalert

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