Navigation Links
Vitamin D supplements do not improve cholesterol as previous research suggested
Date:9/4/2012

Vitamin D has been touted for its beneficial effects on a range of human systems, from enhancing bone health to reducing the risk of developing certain cancers. But it does not improve cholesterol levels, according to a new study conducted at The Rockefeller University Hospital. A team of scientists has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. The finding is published in the journal Arteriosclerosis, Thrombosis and Vascular Biology.

The researchers, led by Manish Ponda, an assistant professor of clinical investigation in Jan Breslow's Laboratory of Biochemical Genetics and Metabolism, studied 151 people with vitamin D deficiency. The study participants were given either 50,000 internationals units of vitamin D3 or a placebo weekly for eight weeks. Participants' cholesterol levels were measured before and after treatment.

Correcting vitamin D deficiencies with high doses of oral vitamin D supplements did not change cholesterol levels, Ponda and his colleagues found, despite effectively increasing vitamin D to recommended levels. Vitamin D levels nearly tripled in the group that received supplements, but were unchanged in the placebo group.

"Our study challenges the notion that replenishing vitamin D improves cholesterol," says Ponda. "In fact, a biologic response to vitamin D was correlated with an increase in LDL cholesterol."

Ponda and his colleagues also tested the effect of vitamin D supplementation on lipoprotein particle size and number, biomarkers of cholesterol not typically measured in clinical practice, and found no change in response to increases in vitamin D.

These clinical trial results confirm those from a recent data mining study, published in July in the journal Circulation, conducted by the Breslow lab in collaboration with scientists at Quest Diagnostics. In that study, the researchers
'/>"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
Source:Eurekalert

Page: 1 2

Related biology news :

1. High doses of Vitamin D help tuberculosis patients recover more quickly
2. Vitamin B12 deficiency: Tracing the causes
3. Vitamin B12 deficiency: Tracking the genetic causes
4. Vitamin D supplementation can decrease risk of respiratory infections in children
5. Iron, vitamins could affect physical fitness in adolescents
6. Lower vitamin D could increase risk of dying, especially for frail, older adults
7. Scientists confirm existence of vitamin deserts in the ocean
8. Obesity plus low vitamin D may add up to a greater risk of diabetes
9. Low vitamin D levels linked to weight gain in some older women
10. Link between vitamin C and twins can increase seed production in crops
11. 15th Vitamin D Workshop begins tomorrow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... Like discriminating thieves, prostate cancer tumors scavenge and hoard ... But such avarice may be a fatal weakness. ... to kill prostate cancer cells by delivering a trove ... the diseased cells brimming with the mineral, leaving non-cancer ... drugs already commercially available for other uses, could soon ...
(Date:10/14/2014)... Mount Sinai-led research team has discovered a new kind of ... a cell that lines liver blood vessels, according to a ... . The existence of such a cell type contradicts current ... embryo, and may hold clues to origins of, and future ... from a single cell into a complex being made up ...
(Date:10/14/2014)... cancer likely takes between 10 and 20 years ... "broad window" of intervention if detected early, which ... predisposition, say Australian clinical researchers. , Dr ... Garvan Institute of Medical Research, analysed medical histories ... 766 pancreatic cancer patients, operated on between 1994 ...
Breaking Biology News(10 mins):Prostate cancer's penchant for copper may be a fatal flaw 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3Early detection window when pancreatic cancer is in the family 2
... pathologist at the University of California, Riverside has identified a ... general decline of several backyard avocado and landscape trees in ... a new species of Fusarium . ... is transmitted by the Tea Shot Hole Borer ...
... 7, 2012 - A new innovation can completely reshape an ... genetically engineered (GE) crops in the 1980,s ignited a buzz ... yields and better nutritional content, along with the reduction of ... a significant role in the U.S., with more than 160 ...
... Athens, Ga. A basic tenet underpinning scientists, ... longer than their less abundant counterparts, but a new ... relationship. A team of scientists analyzed more than ... numbers did indeed help clam-like brachiopods survive the Ordovician ...
Cached Biology News:Beetle-fungus disease threatens crops and landscape trees in Southern California 2New research reveals challenges in genetically engineered crop regulatory process 2New research reveals challenges in genetically engineered crop regulatory process 3UGA study finds there's not always safety in numbers when it comes to extinction risk 2UGA study finds there's not always safety in numbers when it comes to extinction risk 3
(Date:10/18/2014)... The Asia-Pacific Bio-based Advanced Phase Change Materials Market ... change material market in Asia-Pacific with analysis and ... of the Asia-Pacific Bio-based Advanced Phase Change Materials ... in-depth analysis provided. This also provides a glimpse ... phase change material market, and is supported by ...
(Date:10/18/2014)... The Asia-Pacific Liquid Crystal on Silicon (LCoS) ... in Asia-Pacific with analysis and forecast of revenue. This ... is expected to reach $380.0 million by 2018, at ... Browse through the TOC of the Asia-Pacific LCoS display ... analysis provided. This also provides a glimpse of the ...
(Date:10/18/2014)... The report " Cloud Analytics Market ... Speech; Machine; Video; Predictive Analytics: Global Advancements, Delivery ... Analysis (2013 - 2018) ", defines and segments ... segments with an in-depth analysis and forecasting of ... driving this market, various restraints, and opportunities impacting ...
(Date:10/17/2014)... SAN DIEGO and HILDEN, ...   , Translational research ... new capabilities being presented at the American Society ... Volume of 250,000-plus DNA samples linked to Ingenuity ... superior depth for genomic analysis  Ingenuity ...
Breaking Biology Technology:The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 4The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Liquid Crystal on Silicon (LCoS) display market is expected to reach $380.0 million by 2018 - New Report by MicroMarket Monitor 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 2Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 3Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 4Cloud Analytics Market (by Cloud Business Intelligence & Predictive Analytics) Expected to Cross $16.52 Billion by 2018 - New Report by MarketsandMarkets 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... Wash., Sept. 28 Clarisonic announced today the expansion ... a partnership with Look Good…Feel Better ... helps women with breast and other cancers manage their ... Through the program,s free workshops, volunteer beauty professionals teach ...
... Sept. 28 The Michael J. Fox Foundation has ... ), the first-ever large-scale clinical study exclusively focused on ... A biomarker is required to efficiently test potentially life-transforming ... of Parkinson,s disease — something no PD treatment on ...
... been awarded joint funding for a research project that ... detection and eradication of Tuberculosis (TB), across the world. ... Technologies (Orla) have been awarded 91,000 by the Technology ... of TB. The project, which begins in ...
Cached Biology Technology:Clarisonic Empowers Cancer Patients to Put Their Best Face Forward 2Clarisonic Empowers Cancer Patients to Put Their Best Face Forward 3Clarisonic Empowers Cancer Patients to Put Their Best Face Forward 4Clarisonic Empowers Cancer Patients to Put Their Best Face Forward 5Michael J. Fox Foundation Launches Parkinson's Progression Markers Initiative (PPMI) 2Michael J. Fox Foundation Launches Parkinson's Progression Markers Initiative (PPMI) 3Michael J. Fox Foundation Launches Parkinson's Progression Markers Initiative (PPMI) 4Michael J. Fox Foundation Launches Parkinson's Progression Markers Initiative (PPMI) 5Michael J. Fox Foundation Launches Parkinson's Progression Markers Initiative (PPMI) 6Michael J. Fox Foundation Launches Parkinson's Progression Markers Initiative (PPMI) 7Nanobiotechnology experts join forces to improve TB testing 2
... Tracker Intracellular Localization Kit with TransIT-siQUEST ... approach to directly label and deliver ... efficient yet non-destructive manner, for in ... functional inhibition of target gene expression ...
... mir Vana miRNA Bioarray Essentials Kit provides ... and post-hybridization washing of the mir Vana ... has been labeled using Ambions mir Vana ... positive control miRNA (Bioarray ID BA10001) that should ...
... The Label IT siRNA Tracker Intracellular ... to directly label and deliver siRNA, of ... manner, for in vitro tracking experiments. Subcellular ... expression can be monitored following introduction of ...
... is a new product number, ... product number. If showing no ... the old Sigma-Aldrich number (Z71,344-9) ... assistance. ID clarifier: box holds ...
Biology Products: