Navigation Links
Vitamin D supplements do not improve cholesterol as previous research suggested
Date:9/4/2012

Vitamin D has been touted for its beneficial effects on a range of human systems, from enhancing bone health to reducing the risk of developing certain cancers. But it does not improve cholesterol levels, according to a new study conducted at The Rockefeller University Hospital. A team of scientists has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. The finding is published in the journal Arteriosclerosis, Thrombosis and Vascular Biology.

The researchers, led by Manish Ponda, an assistant professor of clinical investigation in Jan Breslow's Laboratory of Biochemical Genetics and Metabolism, studied 151 people with vitamin D deficiency. The study participants were given either 50,000 internationals units of vitamin D3 or a placebo weekly for eight weeks. Participants' cholesterol levels were measured before and after treatment.

Correcting vitamin D deficiencies with high doses of oral vitamin D supplements did not change cholesterol levels, Ponda and his colleagues found, despite effectively increasing vitamin D to recommended levels. Vitamin D levels nearly tripled in the group that received supplements, but were unchanged in the placebo group.

"Our study challenges the notion that replenishing vitamin D improves cholesterol," says Ponda. "In fact, a biologic response to vitamin D was correlated with an increase in LDL cholesterol."

Ponda and his colleagues also tested the effect of vitamin D supplementation on lipoprotein particle size and number, biomarkers of cholesterol not typically measured in clinical practice, and found no change in response to increases in vitamin D.

These clinical trial results confirm those from a recent data mining study, published in July in the journal Circulation, conducted by the Breslow lab in collaboration with scientists at Quest Diagnostics. In that study, the researchers
'/>"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
Source:Eurekalert

Page: 1 2

Related biology news :

1. High doses of Vitamin D help tuberculosis patients recover more quickly
2. Vitamin B12 deficiency: Tracing the causes
3. Vitamin B12 deficiency: Tracking the genetic causes
4. Vitamin D supplementation can decrease risk of respiratory infections in children
5. Iron, vitamins could affect physical fitness in adolescents
6. Lower vitamin D could increase risk of dying, especially for frail, older adults
7. Scientists confirm existence of vitamin deserts in the ocean
8. Obesity plus low vitamin D may add up to a greater risk of diabetes
9. Low vitamin D levels linked to weight gain in some older women
10. Link between vitamin C and twins can increase seed production in crops
11. 15th Vitamin D Workshop begins tomorrow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... VALLEY, Calif., August 19, 2014 -- Bay Area Lyme ... diagnose and simple to cure, applauds new research published ... journal Ticks and Tick-borne Diseases . The ... Northwest California are active throughout the year, making the ... by researchers at California Department of Public Health (CDPH) ...
(Date:8/20/2014)... Ore. -- When are athletes who have suffered concussions ... Oregon study has found that high school athletes who ... 60 days experience a significant regression in their abilities ... The regression, as seen in changes in their balance ... 19 athletes. Ten of the 12 had returned to ...
(Date:8/20/2014)... During the past few years, Virginia Tech,s Wu Feng ... Microsoft grant from the "Computing in the Cloud" program, ... a $6 million award from the Air Force on ... from NSF and the National Institutes of Health on ... wove together the "parallel computing" aspects from each grant, ...
Breaking Biology News(10 mins):Lyme disease risk is year-round in Northwest California, according to new study 2Lyme disease risk is year-round in Northwest California, according to new study 3Recovery reversal seen in Oregon study of returning concussed athletes 2Recovery reversal seen in Oregon study of returning concussed athletes 3The internet was delivered to the masses; parallel computing is not far behind 2The internet was delivered to the masses; parallel computing is not far behind 3The internet was delivered to the masses; parallel computing is not far behind 4
... also available in Chinese on EurekAlert! Chinese ... scientists have published new research that improves the survival and ... Hsiao Chang Chan, from the Chinese University of Hong Kong, ... differentiation has led to a variety of breakthroughs as stem ...
... and alcohol serve as gateway drugs, which people use ... to cocaine and other illicit substances; this progression is ... in Science Translational Medicine by Amir Levine, ... at Columbia University Medical Center provides the first molecular ...
... want to get a jump on the latest news in ... Graduate Student Research Day set for Nov. 9, 2011. ... an opportunity for the best and brightest graduate students to ... Students from Stevens Institute of Technology, Rutgers University ...
Cached Biology News:Reprogramming stem cells to a more basic form results in more effective transplant, study shows 2Nicotine primes brain for cocaine use: Molecular basis of gateway sequence of drug use 2NJIT grad students display work at 7th annual Research Day on Nov. 9 2
(Date:8/21/2014)... 21, 2014 On Wednesday of last week ... use Redox Signaling molecules, became available for purchase in Australia ... "The way that RENU 28 works is, if you think ... of the rate of cellular renewal within your body. If ... of that rate of cellular renewal. What RENU 28 does ...
(Date:8/20/2014)... of patented university inventions licensed to biotechnology firms ... commercialization. To open these roadblocks, the researchers suggest ... the discovery stage could lead to faster commercialization ... derived from discoveries made in university laboratories and ... during clinical trials, which have a high failure ...
(Date:8/20/2014)... time, chemists have succeeded in measuring vibrational motion of ... study reveals how vibration of a single molecule differs ... The study was performed at the University of California, ... of Jyvskyl works as a visiting fellow under professor ... The second team was lead by Professor Eric O. ...
(Date:8/20/2014)... High performance computing (HPC) will ... complete climate and Earth system model to address ... , Eight national laboratories, including Lawrence Livermore ... for Atmospheric Research, four academic institutions and one ... national laboratories include Argonne, Brookhaven, Lawrence Berkeley, Los ...
Breaking Biology Technology:RENU 28 Skin Care Now Available in Australia and New Zealand 2Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3Seeing a molecule breathe 2New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3
... GeneGo, Inc., the leading systems biology tools company, ... curated pathway maps from GeneGo, Inc. for their ... www.millipore.com/pathways , the tool links Millipore,s cutting edge ... bioinformatics content to related biological pathways. These maps ...
... company Pharmaxis,(ASX: PXS; Nasdaq: PXSL ) today ... senior management team in the position of Chief Medical ... pharmacovigilance and,medical affairs. Clinical Operations will continue to ... Dr Fox has more than 15 ...
... Sirion Therapeutics, Inc., a privately held ophthalmic-focused biopharmaceutical ... an agreement with Advanced Vision Research, Inc. (AVR) ... AVR,s new MacuTrition(R) oral retinal nutritional supplement and ... gland therapy. AVR is a privately held ophthalmic ...
Cached Biology Technology:Millipore Launches an Interactive Biological Pathway Tool Using GeneGo's Manually Curated Pathway Maps 2Millipore Launches an Interactive Biological Pathway Tool Using GeneGo's Manually Curated Pathway Maps 3Pharmaxis Builds Senior Management Team 2Sirion Therapeutics Partners With Advanced Vision Research (TheraTears(R)) to Promote Products for Retinal and Meibomian Gland Health 2Sirion Therapeutics Partners With Advanced Vision Research (TheraTears(R)) to Promote Products for Retinal and Meibomian Gland Health 3
... monoclonal [198C679.2.1] to Presenilin 2 Alzheimer's ... of the disease carry mutations in the ... precursor protein (APP). These disease-linked mutations result ... of amyloid-beta (main component of amyloid deposits ...
Human Presenilin-2 NTF Affinity Purified Polyclonal Ab...
5-bromo-2'-deoxyuridine (BrdU) Cell Biology Cell Proliferation Bromodeoxyuridine (BrdU) and Related Products...
2'-Fluorine-CTP (2'-F-CTP) is readily incorporated into transcripts by T7 and SP6 R&DNA™ Polymerase and is available separately....
Biology Products: