Navigation Links
Vitamin D supplements do not improve cholesterol as previous research suggested
Date:9/4/2012

Vitamin D has been touted for its beneficial effects on a range of human systems, from enhancing bone health to reducing the risk of developing certain cancers. But it does not improve cholesterol levels, according to a new study conducted at The Rockefeller University Hospital. A team of scientists has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. The finding is published in the journal Arteriosclerosis, Thrombosis and Vascular Biology.

The researchers, led by Manish Ponda, an assistant professor of clinical investigation in Jan Breslow's Laboratory of Biochemical Genetics and Metabolism, studied 151 people with vitamin D deficiency. The study participants were given either 50,000 internationals units of vitamin D3 or a placebo weekly for eight weeks. Participants' cholesterol levels were measured before and after treatment.

Correcting vitamin D deficiencies with high doses of oral vitamin D supplements did not change cholesterol levels, Ponda and his colleagues found, despite effectively increasing vitamin D to recommended levels. Vitamin D levels nearly tripled in the group that received supplements, but were unchanged in the placebo group.

"Our study challenges the notion that replenishing vitamin D improves cholesterol," says Ponda. "In fact, a biologic response to vitamin D was correlated with an increase in LDL cholesterol."

Ponda and his colleagues also tested the effect of vitamin D supplementation on lipoprotein particle size and number, biomarkers of cholesterol not typically measured in clinical practice, and found no change in response to increases in vitamin D.

These clinical trial results confirm those from a recent data mining study, published in July in the journal Circulation, conducted by the Breslow lab in collaboration with scientists at Quest Diagnostics. In that study, the researchers
'/>"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
Source:Eurekalert

Page: 1 2

Related biology news :

1. High doses of Vitamin D help tuberculosis patients recover more quickly
2. Vitamin B12 deficiency: Tracing the causes
3. Vitamin B12 deficiency: Tracking the genetic causes
4. Vitamin D supplementation can decrease risk of respiratory infections in children
5. Iron, vitamins could affect physical fitness in adolescents
6. Lower vitamin D could increase risk of dying, especially for frail, older adults
7. Scientists confirm existence of vitamin deserts in the ocean
8. Obesity plus low vitamin D may add up to a greater risk of diabetes
9. Low vitamin D levels linked to weight gain in some older women
10. Link between vitamin C and twins can increase seed production in crops
11. 15th Vitamin D Workshop begins tomorrow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... A multi-institutional team of researchers has developed a ... This safe, noninvasive method for assessing the function and ... lead to better diagnosis and treatment of gut diseases. ... overgrowth, irritable bowel syndrome and inflammatory bowel disease all ... side effects in patients with diseases such as diabetes ...
(Date:7/24/2014)... These molecules, which have similar counterparts in humans, affect ... of nerve signals into the hippocampus, an area of ... processes and the creation of memories. The results of ... Neuron . , Brain function depends on the active ... purpose, neurons are woven together into a dense network ...
(Date:7/24/2014)... the United States, wildland managers often utilize the silvicultural ... (ladder fuels). These cuttings and other post-logging debris ... in order to dispose of the material. To improve ... cover all or part of the debris pile with ... in order to keep water out. A recent study ...
Breaking Biology News(10 mins):New imaging agent provides better picture of the gut 2A protein couple controls flow of information into the brain's memory center 2A protein couple controls flow of information into the brain's memory center 3A protein couple controls flow of information into the brain's memory center 4Study gives new perspective on agricultural plastic, debris burning, and air quality 2
... LANSING, Mich. Diversity is valuable socially, economically and ... has found that growing more corn to produce ethanol ... of beneficial insects to control pests, a loss valued ... states studied (Michigan, Iowa, Minnesota and Wisconsin). "Corn ...
... R.I. December 15, 2008 The elevated carbon dioxide ... 2100 will likely lead to physiological impairments of jumbo (or ... Island scientists. The results of a study by Brad Seibel, ... former URI post-doctoral student now on the faculty at the ...
... and adults with the blood cancer mixed-lineage leukemia (MLL) typically ... first birthdays. Although there are varying causes of MLL, most ... MLL and the AF4 genes. When ... potent cancer-causing oncogene is created. Although researchers have known that ...
Cached Biology News:Diverse landscapes are better: Policymakers urged to think broadly about biofuel crops 2Ocean acidification from CO2 emissions will cause physiological impairment to jumbo squid 2Tracking the molecular pathway to mixed-lineage leukemia 2
(Date:7/24/2014)... PRINCETON, N.J. , July 24, 2014 /PRNewswire/ ... largest provider of regulatory and ethical review services ... acquired Alliance Biosciences. Formerly a division of ... Biosciences was the leading biosafety and biosecurity consulting ... . With this addition, WCG,s biosafety division – ...
(Date:7/24/2014)... July 24, 2014  Spherix Incorporated (SPEX) -- an ... monetization of intellectual property, today announced that the Company ... June 30, 2014 on Monday, August 18, 2014 for ... a.m. ET on Monday, August 18, 2014 to discuss ... the company,s CEO, Anthony Hayes . ...
(Date:7/23/2014)... , July 24, 2014 Lyfebulb, the ... Inc. (OTCQX and NASDAQ OMX First North Premier, ... "the Company"), announced a collaboration to increase awareness ... night at an event attended by more than ... Lyfebulb is a health and wellness company dedicated ...
(Date:7/23/2014)... (MIPT and Russian Quantum Center at Skolkovo) and ... and the Institute of Physics in Bratislava, Slovakia) ... of particles passing through an amplifier and, conversely, ... are provided in an article published in the ... , Quantum entangled particles are considered to be ...
Breaking Biology Technology:WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3Spherix Schedules Shareholder Update Call 2Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 2Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 4Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 5Scientists find way to maintain quantum entanglement in amplified signals 2Scientists find way to maintain quantum entanglement in amplified signals 3Scientists find way to maintain quantum entanglement in amplified signals 4
... N.J., Sept. 19, 2011 Palatin Technologies, Inc. (NYSE Amex: ... year 2011 financial results on Thursday, September 22, 2011 before ... will also conduct a conference call and live audio webcast ... which will include discussion of the results of operations in ...
... LA JOLLA, CA September 15, 2011 Researchers at ... which certain viruses such as influenza trigger a type of ... This severe immune reactioncalled a "cytokine storm"floods the tiny ... blocking off airways and damaging body tissues and organs. Cytokine ...
... This evening, Novo Nordisk awarded sponsorships totaling $80,000 to ... educate people living with type 2 diabetes on how ... of long-term diabetes related complications. The sponsorships are part ... new initiative that aims to promote enduring, sustainable change ...
Cached Biology Technology:Scripps Research team discovers treatable mechanism responsible for often deadly response to flu 2Scripps Research team discovers treatable mechanism responsible for often deadly response to flu 3Novo Nordisk and Atlanta Area Organizations Partner on Diabetes Education Programs 2Novo Nordisk and Atlanta Area Organizations Partner on Diabetes Education Programs 3
... for imaging of chemiluminescent, fluorescent and colorimetric ... control for users who wish to change ... A range of high resolution, cooled cameras ... and chemiluminescent applications , Interchangeable filters ...
... features a 4.1 mega pixel digital color ... TLC color images., The cabinet features ... longwave UV tubes positioned on two sides ... fluorescence studies , Interior overhead white ...
Request Info...
... ICE-LAP3 Mch3 Lyophilized ... of enzyme regulation and kinetics, cleavage of target substrates, ... units/mg protein. One unit is defined as ... of Ac-DEVD-pNA Cat. No. 235400 per hour at 37 ...
Biology Products: