Navigation Links
Vitamin D insufficiency linked to bacterial vaginosis in pregnant women
Date:5/14/2009

Bacterial vaginosis (BV) is the most common vaginal infection in US women of childbearing age, and is common in pregnant women. BV occurs when the normal balance of bacteria in the vagina is disrupted and replaced by an overgrowth of certain bacteria. Because having BV puts a woman at increased risk for a variety of complications, such as preterm delivery, there is great interest in understanding how it can be prevented. Vitamin D may play a role in BV because it exerts influence over a number of aspects of the immune system. This hypothesis is circumstantially supported by the fact that BV is far more common in black than white women, and vitamin D status is substantially lower in black than white women. This relation, however, has not been rigorously studied. To assess whether poor vitamin D status may play a role in predisposing a woman to BV, Bodnar and coworkers at the University of Pittsburgh and the Magee-Womens Research Institute studied 469 pregnant women. The results of their investigation are published in the June 2009 issue of the Journal of Nutrition.

This prospective epidemiologic study investigated the relation between vitamin D status and BV in 209 white and 260 black women at <16 wk of pregnancy with singleton gestations. Blood samples were taken, and serum analyzed for 25-hydroxyvitamin D [25(OH)D], a marker of vitamin D status. 25(OH)D levels below 80 nmol/L are typically considered insufficient. Pelvic examinations were performed, and Gram-stained vaginal smears were assessed to diagnose BV.

The data indicate that 41% of all enrolled women had BV, and that 93% had 25(OH)D levels indicative of vitamin D insufficiency. Overall, women with BV had lower serum 25(OH)D concentrations than those without BV (P < 0.01). The prevalence of BV decreased as vitamin D concentration increased to 80 nmol/L (P < 0.001). Compared with 75 nmol/L, serum 25(OH)D concentrations of 20 nmol/L and 50 nmol/L were associated with 65% and 26% increases, respectively, in the likelihood of BV. In summary, these findings suggest that vitamin D insufficiency is associated with BV in the first 4 mo of pregnancy. Further, poor vitamin D status may contribute to the strong racial disparity in the prevalence of BV in US women. Controlled intervention trials will be needed to confirm this hypothesis.


'/>"/>

Contact: Suzanne Price
sprice@nutrition.org
American Society for Nutrition
Source:Eurekalert

Related biology news :

1. Low vitamin D during pregnancy linked to pre-eclampsia
2. Low vitamin D linked to higher risk of hip fracture
3. Vitamin E trials fatally flawed
4. Study shows vitamin C is essential for plant growth
5. Could vitamin D, a key milk nutrient, affect how you age?
6. Vitamin B-12 function may be diminished by excessive folate
7. Jefferson scientists studying the effects of high-dose vitamin C on non-Hodgkin lymphoma patients
8. New way to produce high-vitamin corn could improve nutrition in developing countries
9. Team finds an economical way to boost the vitamin A content of maize
10. Vitamin E may increase tuberculosis risk in male smokers with high vitamin C intake
11. Vitamin D and calcium influence cell death in the colon, researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... , Feb. 11, 2016  According to new research ... mainstream. More than 200 fingerprint, iris, and eye-vein ... under 70 brand names. This includes market leaders ... ZTE. Acuity projects that 600 million biometric smartphones ... global installed base. Maxine Most , ...
(Date:2/11/2016)...  Vigilant Solutions announces today that its license plate recognition ... Lee,s Summit Police Department to improve ... of a homicide suspect. Kansas City ... square miles and is home to roughly 100,000 residents. ... mobile license plate reader system and also leverages Vigilant,s network ...
(Date:2/10/2016)... India , February 10, 2016 /PRNewswire/ ... --> According to 2016 iris recognition ... identification iris recognition is more widely accepted ... available with both fingerprint and iris recognition ... the user to avoid purchasing two individual ...
Breaking Biology News(10 mins):
(Date:2/13/2016)... ... February 13, 2016 , ... Meadowlark ... announce the launch of two new analog SLMs with resolutions of 1920 x ... incident light in amplitude, phase, or the combination of both on a pixel-by-pixel ...
(Date:2/12/2016)... ... February 12, 2016 , ... Global Stem Cells Group ... new stem cell treatment center in Quito, Ecuador, Feb. 24-March 6, 2016. The new ... around the world. , Global Stem Cells Group CEO Benito Novas will host ...
(Date:2/12/2016)... SAN DIEGO , Feb. 12, 2016 Biocom, ... life science community, took a group of San ... as part of its 2016 Precision Medicine Advocacy Fly-In. ... at the Food and Drug Administration (FDA), the Centers for ... (NIH), as well as San Diego U.S. Representatives Susan ...
(Date:2/12/2016)... PA (PRWEB) , ... February 12, 2016 , ... ... at the Georgia World Congress Center in Atlanta, Georgia, will include 848 exhibitors ... These leading companies will be displaying products and services used by the scientific ...
Breaking Biology Technology: