Navigation Links
Vitamin C: A potential life-saving treatment for sepsis
Date:11/17/2010

Physicians caring for patients with sepsis may soon have a new safe and cost-effective treatment for this life-threatening illness. Research led by Dr. Karel Tyml and his colleagues at The University of Western Ontario and Lawson Health Research Institute have found that vitamin C can not only prevent the onset of sepsis, but can reverse the disease.

Sepsis is caused by a bacterial infection that can begin anywhere in your body. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, the elderly and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from the disease.

According to Dr. Tyml, a professor at Western's Schulich School of Medicine & Dentistry, patients with severe sepsis have a high mortality rate, nearly 40 percent, because there is no effective treatment.

"There are many facets to sepsis, but the one we have focused on for the past 10 years is the plugging of capillaries," says Dr. Tyml. Plugged capillaries prevent oxygenation and the supply of life-supporting materials to your organ tissue and stop the removal of metabolic waste product. Plugged capillaries are seen in organs of septic patients. These organs may eventually fail, leading to multiple organ failure and death. Dr. Tyml's lab was the first to discover this plugging by using intravital microscopy, a technique Dr. Tyml pioneered in Canada.

According to Dr. Tyml's most recent publication, oxidative stress and the activated blood clotting pathway are the major factors responsible for the capillary plugging in sepsis. Through his research, Dr. Tyml has discovered that a single bolus of vitamin C injected early at the time of induction of sepsis, prevents capillary plugging. He has also found that a delayed bolus injection of vitamin C ca
'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Page: 1 2

Related biology news :

1. Vitamin D deficit doubles risk of stroke in whites, but not in blacks
2. Burn injuries rapidly deplete vitamin E
3. Vitamin E in front line of prostate cancer fight
4. Vitamin C rapidly improves emotional state of acutely hospitalized patients, say LDI researchers
5. BUSM researchers to study vitamin D production in fat malabsorption patients
6. Iowa State study finds corn bred to contain beta-carotene is a good source of vitamin A
7. Vitamin A increases the presence of the HIV virus in breast milk
8. Stomach bacteria need vitamin to establish infection
9. Biochemist proposes worldwide policy change to step up daily vitamin D intake
10. Vitamin deficiency after weight loss surgery can cause vision loss in newborns
11. More than half the worlds population gets insufficient vitamin D, says UCR biochemist
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... 2015 Genisphere announced Tom ... help further develop Genisphere,s therapeutics capabilities and portfolio. Mr. ... spent much of the last 25 years in leadership ... and Johnson & Johnson. Tom started his career in ... Corporate Finance. He graduated from Dartmouth College with a ...
(Date:6/25/2015)... 25, 2015  TAKE Solutions Ltd., a global business ... United States Patent and Trademark Office (USPTO) for its ... TAKE Solutions, Clinical Accelerators to reduce the time taken ... to standardization without the accelerators), thus reducing time to ... At the heart of the patented Clinical Data ...
(Date:6/24/2015)... June 24, 2015 Biometry authentication provider ... biometric password solution one face in. ... one face in, entering the expanding biometric ... affordable multifactor-authentication biometric answer to the password problem. ... in partnership with KeyLemon, one face in allows ...
Breaking Biology News(10 mins):Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3TAKE Solutions Awarded Patent By USPTO 2KeyLemon Announces Partnership With Biometric Password Solution onefacein 2
... 2008) Black bears that live around urban areas weigh ... likely to die violent deaths, according to a study by ... Fall 2008 issue of the journal Human-Wildlife Conflicts, ... areas around Lake Tahoe, Nevada and compared them to 10 ...
... The Marine Board-ESF published its 13th Position Paper, which ... research needed to assess the effects of anthropogenic sound ... Marine Board Position Paper 13 results from the activities ... and marine mammals convened at the joint European Marine ...
... Letters, Steve Brusatte, Professor Michael Benton, and colleagues ... not proliferate immediately after they originated, but that their ... by two mass extinctions. "The sheer size ... something special about these animals that preordained them for ...
Cached Biology News:Study: urban black bears 'live fast, die young' 2Effects of anthropogenic sound on marine mammals -- a research strategy 2Mass extinctions and the evolution of dinosaurs 2
(Date:7/27/2015)... 2015 According to the new Market ... Pre-formulated Media), by Application (Biobanking, Regenerative Medicine, Drug Discovery), by ... , Asia-Pacific , Rest of the ... media market was valued at $247.7 million in 2014, which ... at a CAGR of 18.2% between 2014 and 2019. ...
(Date:7/27/2015)... , July 27, 2015 IDEXX Laboratories, ... than 8,000 clinics have submitted over 100,000 specimens to ... in just the first 10 days since the breakthrough ... disease (CKD) is a leading cause of suffering and ... submitted specimens are consistent with generally accepted kidney disease ...
(Date:7/25/2015)... ... July 25, 2015 , ... Technology leader Anton Paar ... and adjusts the surface temperature of the measuring prism. This is required to ... traceability and documentation are key requirements. It is likely that no refractometer manufacturers ...
(Date:7/24/2015)... NEW YORK , July 24, 2015 ... the following equities: PDL BioPharma Inc. (NASDAQ: PDLI ... Inc. (NASDAQ: STEM ), Northwest Biotherapeutics Inc. (NASDAQ: ... ACOR ). Free research report on PDL BioPharma can ... 23, 2015, the NASDAQ Composite ended at 5,146.41, down ...
Breaking Biology Technology:Global Biopreservation Media Market to be Worth $571.5 Million by 2019 2Global Biopreservation Media Market to be Worth $571.5 Million by 2019 3Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 2Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 3Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 4Over 100,000 Pets Tested with New IDEXX SDMA Kidney Function Test Since Product Launch on July 13 5It’s T-Time for Refractometers: On-site Temperature Check Now Available 2Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 2Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 3Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 4Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 5
... Dec. 8 Kaiser Permanente Chairman and Chief,Executive ... today,at the World Healthcare Innovation and Technology conference ... Healthcare: Groundbreaking Innovations and,their Impact on Healthcare Delivery," ... care system where data and connectivity enable patient-centered ...
... SUNNYVALE, Calif., Dec. 8 Accuray Incorporated,(Nasdaq: ... field of radiosurgery, announced today,that 150 CyberKnife(R) Robotic ... milestone was achieved when Hospital Corporation of America,(HCA), ... System in,collaboration with consultant clinician partners at The ...
... (Amex: ETC ) ("ETC" or the "Company") ... BARA-MED(R)XD Monoplace hyperbaric oxygen chambers in the St. John ... chambers are the first computer-controlled hyperbaric chambers to be ... , Hyperbaric oxygen (HBO) chambers offer ...
Cached Biology Technology:Kaiser Permanente CEO Calls for 'Connected' Health Care 2Kaiser Permanente CEO Calls for 'Connected' Health Care 3Accuray Achieves Milestone of 150th CyberKnife System Installed Worldwide 2Accuray Achieves Milestone of 150th CyberKnife System Installed Worldwide 3Accuray Achieves Milestone of 150th CyberKnife System Installed Worldwide 4Environmental Tectonics Corporation Announces Placement of Two Monoplace Chambers at St. John Wound Center; First Computer-controlled Hyperbaric Chambers in Oklahoma 2Environmental Tectonics Corporation Announces Placement of Two Monoplace Chambers at St. John Wound Center; First Computer-controlled Hyperbaric Chambers in Oklahoma 3Environmental Tectonics Corporation Announces Placement of Two Monoplace Chambers at St. John Wound Center; First Computer-controlled Hyperbaric Chambers in Oklahoma 4
...
... The 500 optimization kit is for fine-tuning ... interest. The kit is recommended when you ... system. The kit includes 0.25 g each ... micrometer diameter gold microcarriers, 100 each of ...
... marker is specifically designed for two-dimensional ... The four proteins in this marker ... diagonal pattern across a 2D gel. ... 3.8. Mol wt: ...
... can be used to test the crossreactivity ... sera that are commonly used as blocking ... spots for 21 different protein preparations on ... crossreactivity and species specificity, QC of purified ...
Biology Products: