Navigation Links
Visionary concept earns La Jolla Institute scientist prestigious NIH Pioneer Award
Date:9/24/2009

ombination of abilities which have allowed her to make seminal research contributions," said Dr. Shastri, noting that Dr. Cheroutre's previous discoveries have opened up novel avenues of research on the molecular mechanisms of immunological memory, regulatory T cells and autoimmunity. "She not only questions dogmas, but also designs appropriate experiments and has the persistence to carry through until the problems are resolved. She is simply one of the best."

Dr. Cheroutre's proposal focuses on pinpointing specific molecular and genetic events that, she believes, could lay at the basis of susceptibility to autoimmunity. She also will work toward developing innovative treatment, and even more far-reaching approaches, that might prevent autoimmunity in those susceptible individuals. Autoimmunity occurs when the body's white blood cells mistakenly attack normal cells. This leads to a host of disorders such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis. "Normally, the immune system provides us protection against pathogens and the generation of transformed cancer cells," said Dr. Cheroutre. "But in autoimmunity, the immune system does not seem to be able to distinguish bad from good cells. It's like the body gets caught in friendly fire. It can cause incredible self-destruction."

If Dr. Cheroutre's premise is correct -- and she proves that certain cellular defects underlie autoimmunity -- it could allow for early detection of those individuals at high risk. "If true, it would enable us to detect at birth whether an individual is genetically prone to autoimmunity."

The second part of her groundbreaking proposal would then come into play through the development of new therapies that could potentially prevent autoimmunity in those people identified as highly susceptible. Theoretically, similar treatments could also be used for those who have already developed autoimmunity.

"If successful, an individual c
'/>"/>

Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. NYU biologist Bonneau named among 20 "visionary" scientists under 40 by Discover magazine
2. Heat stress influences low conception of dairy herds
3. Misconceptions about Alzheimers varies among races, survey suggests
4. New Delft material concept for aircraft wings could save billions
5. Resilience concepts poised to aid management of coastal marine ecosystems
6. Moms obesity during conception phase may set the stage for offsprings obesity risk
7. Aquaculture concept leaves judges goggle eyed
8. Children born after donor insemination should be told as soon as possible about their conception
9. New roadside beautification concept studied
10. PTC124 shows activity in cystic fibrosis; Phase 2 proof-of-concept data published in Lancet
11. M&Ms as diet food? 100-calorie pack misconceptions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... of researchers, including scientists from the Max Planck Institute ... a major step in understanding photosynthesis, the process by ... oxygen in its atmosphere and which is therefore crucial ... , The researchers report the first direct visualization of ... step in which a specific protein complex, photosystem II, ...
(Date:7/11/2014)... Recent evidence has demonstrated that transplantation of mesenchymal stem ... rat or mouse models of Alzheimer,s disease (AD) and ... cerebral ischemia. Few studies are reported on the therapeutic ... with AD and on the effect on oxidative injury ... Yufang Yan and her team, School of Life Sciences, ...
(Date:7/11/2014)... Research and Markets has announced the addition ... Analysis Size Share Growth Trends and Forecast to 2019" ... http://photos.prnewswire.com/prnh/20130307/600769 The rising number of ... high level security in both private and public sector. ... and passwords, tokens etc. are vulnerable to attacks. Biometrics ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2
... Listeria monocytogenes invades the body, it commandeers its host ... report published in the Journal of Biological Chemistry, a ... behind this infection technique. , The research appears as ... issue of the Journal of Biological Chemistry, an American ...
... analysis published in the Feb. 8 PNAS supports the ... , Researchers in California, Israel, and Germany have compared ... the fruit fly ?and reported that protein "wiring" connections ... This first-of-its-kind analysis of three higher level organisms published ...
... Bioengineering and Nanotechnology (IBN) has developed a novel method ... which can be used in pharmaceutical synthesis and novel ... in the leading Chemistry journal, Angewandte Chemie, and a ... , Research Scientist Dr. Yu Han and IBN Executive ...
Cached Biology News:Scientists discover that host cell lipids facilitate bacterial movement 2Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits 2Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits 3Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits 4Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications 2
(Date:7/11/2014)... DUBLIN , July 11, 2014 ... in part) in, into or from any jurisdiction where to ... of such jurisdiction.  Shire plc ("Shire" or the ... Bloomberg article this afternoon.  Shire confirms it has held a ... being made by Shire without the prior agreement or approval ...
(Date:7/11/2014)... 2014 /CNW/ - Sunovion Pharmaceuticals Canada Inc. (Sunovion) today ... acetate) for use as a once-daily adjunctive therapy for ... who are not satisfactorily controlled with conventional therapy.  APTIOM ... under 18 years of age. Epilepsy ... according to Epilepsy Canada, it affects 0.6% of the ...
(Date:7/10/2014)... Product and process impurities in biopharmaceuticals ... are often “lost in the noise,” making their ... Dr. Rowel Tobias, Senior Scientist, Protein Chemistry at ... Quality at Nanotherapeutics, Inc., to lear about a ... and quantitation while achieving the required specificity and ...
(Date:7/10/2014)... CA (PRWEB) July 10, 2014 Unraveling ... closer together. The Archer Family purchased a ... within DNA, but ended up with a lifetime of ... contained within the family members’ DNA genuinely brought the ... decided to search deeper into genetic history and prior ...
Breaking Biology Technology:Shire plc - Statement re: Media Speculation 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 3Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 4Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5
... Israel and JERSEY CITY, New Jersey, December 5, Rosetta ... the,development of microRNA-based diagnostics and therapeutics, announced today,that it ... on,Thursday, December 10, from 2:30-3:35 pm EST at the ... A live audio webcast of the ...
... developing solutions based on the products of newborn fibroblasts, will be ... of the 21st Century Breakthroughs for Biomedical Research series. , ... ... a regenerative medicine company developing solutions based on the products of ...
... (Nasdaq: BCRX ) announced today that the Company ... clinical data on BCX-4208 at the 50th American Society of ... Francisco, CA from December 6-9, 2008. Forodesine HCl and ... , The schedule for BioCryst,s poster ...
Cached Biology Technology:Rosetta Genomics to Webcast Panel Presentation at RBC Capital Markets 2008 Healthcare Conference 2Rosetta Genomics to Webcast Panel Presentation at RBC Capital Markets 2008 Healthcare Conference 3Histogen Featured on Economic Report Television Series 2BioCryst to Present Three Posters During the 50th American Society of Hematology Annual Meeting and Exposition 2BioCryst to Present Three Posters During the 50th American Society of Hematology Annual Meeting and Exposition 3