Navigation Links
Virus structure inspires novel understanding of onion-like carbon nanoparticles
Date:4/10/2014

Symmetry is ubiquitous in the natural world. It occurs in gemstones and snowflakes and even in biology, an area typically associated with complexity and diversity. There are striking examples: the shapes of virus particles, such as those causing the common cold, are highly symmetrical and look like tiny footballs.

A research programme led by Reidun Twarock at the University of York, UK has developed new mathematical tools to better understand the implications of this high degree of symmetry in these systems. The group pioneered a mathematical theory that reveals unprecedented insights into how different components of a virus, the protein container encapsulating the viral genome and the packaged genome within, mutually constrain each other's structures [Acta Cryst. (2013). A69, 140150 doi:10.1107/S0108767312047150].

A paper recently published in Acta Crystallographica Section A: Foundations and Advances [Acta Cryst. (2014). A70, 162167 doi: 10.1107/S2053273313034220] in collaboration with Pierre-Philippe Dechant from the University of Durham, UK shows that these mathematical tools apply more widely in the natural world and interestingly also account for the structures of Russian-doll-like arrangements of carbon cages known as carbon onions. It was known previously that individual shells could be modeled using symmetry techniques, but the fact that the entire structure is collectively constrained by a single symmetry principle is a surprising new result.

Such insights are crucial for understanding how different components contribute collectively to function. In the case of viruses this work has resulted in a new understanding of the interplay of the viral genome and protein capsid in virus formation, which in turn has opened up novel opportunities for anti-viral intervention that are actively being explored. Similarly, we expect that the work on carbon onions will provide a basis for a better understanding of the structural constraints on their overall organisation and formation, which in the future can be exploited in nanotechnology applications.


'/>"/>

Contact: Jonathan Agbenyega
ja@iucr.org
44-124-434-2878
International Union of Crystallography
Source:Eurekalert  

Related biology news :

1. Researchers discover how the kissing disease virus hijacks human cells
2. Nano-paper filter removes viruses
3. Study fingers chickens, quail, in spread of H7N9 influenza virus
4. New research seeks beneficial qualities of viruses
5. MERS virus widespread in Saudi Arabian camels
6. Now in 3-D: Video of virus-sized particle trying to enter cell
7. RNA sequencing of 750-year-old barley virus sheds new light on the Crusades
8. Engineered virus is effective against triple negative breast cancer cells
9. Findings point to potential treatment for virus causing childhood illnesses
10. FASEB announces 2014 Science Research Conference: Virus Structure and Assembly
11. Pathogenic plant virus jumps to honeybees
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Virus structure inspires novel understanding of onion-like carbon nanoparticles
(Date:5/9/2016)... 2016 Elevay is currently known ... freedom for high net worth professionals seeking travel for ... connected world, there is still no substitute for a ... sealing your deal with a firm handshake. This is ... advantage of citizenship via investment programs like those offered ...
(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
(Date:4/13/2016)...  IMPOWER physicians supporting Medicaid patients in ... standard in telehealth thanks to a new partnership with ... IMPOWER patients can routinely track key health measurements, such ... and, when they opt in, share them with IMPOWER ... local retail location at no cost. By leveraging this ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... TOKYO , June 24, 2016  Regular discussions on ... to take place between the two entities said Poloz. ... in Ottawa , he pointed to the ... and the federal government. ... Poloz said, "Both institutions have common economic goals, why not ...
(Date:6/24/2016)... ... ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension of 8.5 ... end machines that use the more unconventional z-dimension of 20mm. Z-dimension or ... the cuvette holder. , FireflySci has developed several Agilent flow cell product lines ...
(Date:6/23/2016)... Seattle, WA (PRWEB) , ... June 23, 2016 ... ... technology, announces the release of its second eBook, “Clinical Trials Patient Recruitment and ... patient recruitment and retention in this eBook by providing practical tips, tools, and ...
(Date:6/23/2016)... June 23, 2016   Boston Biomedical , ... compounds designed to target cancer stemness pathways, announced ... granted Orphan Drug Designation from the U.S. Food ... gastric cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin ... to inhibit cancer stemness pathways by targeting STAT3, ...
Breaking Biology Technology: