Navigation Links
Virtual skin model reveals secrets of skin aging
Date:6/26/2013

heal a wound or replenish stocks of other cells, a few of them don't go back into sleep mode, so the population slowly reduces," says Dr. Li. "This explains why older skin is slower to heal and in part why our skin changes as we age. By understanding this mechanism better, it might be possible to find ways to combat the effects of aging on our skin."

Computer modelling of skin biology is the latest step in the evolution of skin science. It allows scientists to project the activity of tissues like skin that are difficult to follow in live systems for extended periods. Currently, 3-dimensional cultures of engineered human skin are viable for only a few weeks and clinical studies in humans are only practical for a few months. With the development of in silico models scientists can predict for the first time what happens in skin as it ages year by year even as it ages decade by decade.

"These models permit exploration of hypotheses in very short periods of time, relative to the lab based bench work," says Dr. Upadhyay. "In silico modelling can significantly shorten R&D programs, and help focus subsequent lab or clinical work on the options with the greatest likelihood of succeeding. This is another reason why in silico models are an effective complement to more established research tools and methods."

The ability to follow virtual skin models over decades may be especially important to skin cancer research. Environmental damage caused by UV exposure or chronic wounding can cause sleeping cells to harbor the mutations which cause skin cancers such as basal cell carcinoma, a very aggressive type of skin cancer.

"The stem cells can harbor mutations throughout the years, but with no effect if they're still in sleep mode," explains Dr. Li. "However, when they start to divide to heal a wound for example, this could trigger the cancer. If it's possible to study this phenomenon for long periods of time it may be possible to find ways to preven
'/>"/>

Contact: Dayna Hochstein
dhochstein@spectrumscience.com
202-955-6222
Spectrum
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Real science in virtual school labs
2. A virtual crystal ball
3. Virtual plant planning, retrofitting and maintenance
4. Scripps Research scientists show potent new compound virtually eliminates HIV in cell culture
5. Darwin discovered to be right: Eastern Pacific barrier is virtually impassable by coral species
6. University of Tennessee Space Institute researchers make clinical trials a virtual reality
7. VirtualScopics Schedules Third Quarter 2012 Earnings Announcement
8. U of M to lead international virtual institute studying climatic and human effects on Earth
9. Virtual women reveal more skin, regardless of body proportions
10. UT Dallas researchers pushing the boundaries of virtual reality
11. Virtual vehicle vibrations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... word for chili peppers. Information about archaeological remains of ... of the appearance of words for chili peppers in ... domesticated and highlight the value of multi-proxy data analysis. ... of nine papers presented in a special feature issue ... Sciences on plant and animal domestication edited by ...
(Date:4/17/2014)... NJ. April 16, 2014. Kessler Foundation has been ... million from the Department of Defense Spinal Cord ... principal investigator for the randomized, double-blinded, controlled, multi-site ... bone and muscle strength after spinal cord injury. ... & Engineering Research at Kessler Foundation. Two additional ...
(Date:4/17/2014)... Professor Marc Andr Gauthier and Professor Luca Razzari ... each been awarded large grants from the John ... for Innovation (CFI) for the acquisition of state-of-the-art ... be added matching grants from the Ministre de ... et de la Technologie (MESRST). These new laboratories ...
Breaking Biology News(10 mins):Chickens to chili peppers 2Chickens to chili peppers 3Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2New state-of-the-art biotech and nanotech equipment for INRS 2
... revolutionize biomedical research, scientists have discovered a way to keep ... individual cancer patient alive in the laboratory which previously ... lab after dividing only a few times, and many common ... This new technique, described today online in the American ...
... activities has polluted lakes throughout the Northern Hemisphere for more ... evident even in remote lakes located thousands of miles from ... published in the journal Science Dec. 16, are ... deposits in 36 lakes using an approach similar to aquatic ...
... insects, high risk of attack has led to the ... in the larval stage. One caterpillar may look like ... Though crypsis may have its advantages, University of Florida ... caterpillars using another strategy previously best-known in adult butterflies: ...
Cached Biology News:Georgetown researchers lead discovery expected to significantly change biomedical research 2Nitrogen from humans pollutes remote lakes for more than a century 2Nitrogen from humans pollutes remote lakes for more than a century 3Caterpillars mimic one another for survival 2Caterpillars mimic one another for survival 3
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 ... Almshouse Road, Warrington, Pa. , Details: The Hepatitis ... finding a cure for hepatitis B and improving the quality ... Crystal Ball on Friday, April 11 at Warrington Country Club ...
(Date:1/14/2014)... pet owners drew up their lists of New Year,s resolutions for ... of my furry companion." Nowadays there are pet salons, dog and ... take the little canine or feline darlings along wherever mommy or ... pricey toys at the pet store. But anyone who has ever ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility management software, ... Strategy. In this role, Michelle will work with current and ... the development of iLab products. Her main goal will be ... the scientific community by offering the most advanced, user-friendly, and ...
(Date:1/14/2014)... Kinaxis ®, provider of RapidResponse ®, a cloud-based supply ... ( S&OP ) service, is proud to be a gold ... held at the Hilton San Diego Bayfront, January 30 – ... Kaszas , Director of Supply Chain at Amgen, as she ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... SOUTH SAN FRANCISCO, Calif., Nov. 21 ,Exelixis, Inc. (Nasdaq: ... the company,s president and chief executive officer will present ... 1:00 p.m.,ET / 10:00 a.m. PT on Wednesday, November ... may be accessed in the Event,Calendar page under Investors ...
... denounces life-destructive research in light of ... new discovery, ... have made a significant breakthrough in stem cell research,using adult skin cells ... Scientists from the University of Wisconsin at Madison announced that,they have identified ...
... to shine spotlight on crisis affecting 246 million ... people ... Day, leaders in the U.S. House of Representatives passed House,Concurrent Resolution 211 ... on November 14. Then, the next day, on,World Diabetes Day itself, the ...
Cached Biology Technology:Stem Cell Breakthrough Could End Human Embryonic Experimentation 2Novo Nordisk Applauds Adoption of World Diabetes Day Resolutions by U.S. Congress 2
... Custom Synthesis Service provides you ... to knockdown any gene. We ... base pairs with terminal dT ... other lengths of your choice. ...
Request Info...
...
Complete cell culture media with cytokines...
Biology Products: