The World Health Organization and the Center for Disease Control has recognized antibiotic resistance "as a critical health challenge of our time," said Amy Pruden, a Virginia Tech environmental engineer who is credited with pioneering the concept of antibiotic resistance genes as environmental pollutants.
Pruden said reducing the spread of antibiotic resistance is a critical measure needed to prolong the effectiveness of currently available antibiotics. This is important since "new drug discovery can no longer keep pace with emerging antibiotic-resistant infections," Pruden said.
Pruden is a 2006 National Science Foundation (NSF) CAREER award recipient as well as a 2007 Presidential Early Career Award in Science and Engineering (PECASE) honoree.
Pruden's unique expertise in characterizing environmental sources and pathways of antibiotic resistance has garnered her as lead of a new NSF RAPID grant to study the recent Colorado flood's effect on antibiotic resistance genes. She will work with Mazddak Arabi of Colorado State University and Diana Aga of the University of Buffalo on the project that will improve the understanding of the role the watershed processes play in disseminating resistance.
For more than 10 years, this research team has monitored the watershed of the South Platte River Basin, southwest of Denver, Colo. "We have already generated a robust data set of antibiotic resistance genes and antibiotics, as well as a unique interdisciplinary watershed-scale approach for characterizing the land-use on their distribution," Pruden explained.
The recent Colorado flooding occurred during the week of Sept. 9, 2013, with flood waters affecting 17 counties over a spread of 200 miles north to south, transporting enormous loads of sediment and transforming the semi-arid landscape of the Front Range of Colorado.
When an antibiotic is consumed, researchers have learned that up to 90 percent passes through a body
|Contact: Lynn Nystrom|