Navigation Links
Video released of rapid Alzheimer's improvement after new immune-based treatment

New research into the treatment of Alzheimer's disease reports improvement in language abilities using a novel immune-based approach. A video accompanying the research, published today in the open access journal BMC Neurology, documents rapid language improvement within minutes of using this new treatment.

Building on previous work by the same authors, published in BioMed Central's Journal of Neuroinflammation, this study focuses on the effect of the anti-tumor necrosis factoralpha (TNF-alpha) drug, etanercept, on measures of verbal ability.

TNF-alpha, a critical component of the brain's immune system, normally finely regulates the transmission of neural impulses in the brain. The authors hypothesize that elevated levels of TNF-alpha in Alzheimer's disease interfere with this regulation. To reduce elevated TNF-alpha, the authors utilized a unique perispinal delivery method to administer etanercept.

The new BMC Neurology article provides preliminary evidence that the disrupted neural communication seen in Alzheimer's disease may be reversible.

According to the lead author of the study, Edward Tobinick, "There are limitations to the data presented; the clinical trial was open label, and not controlled. These caveats notwithstanding, the scientific rationale for the further investigation of anti-TNF-alpha treatment of Alzheimer's disease is compelling. In addition, family members, independent neurologists, and other independent observers have confirmed the clinical, cognitive, and behavioral improvement noted".

Disruption of language function, such as the ability to find words, is a common symptom in advancing Alzheimer's disease, and this BMC Neurology article is one of the first to suggest the possibility of a new therapeutic approach that may address these symptoms.


Contact: Graeme Baldwin
BioMed Central

Page: 1

Related biology news :

1. Fixing the education digital disconnect one video game at a time
2. May 14 AAAS Lecture and videoteleconference on artworks by Siberian schoolchildren
3. Vobile Launches VideoDNA Live; Enables Real-Time Digital Content Protection for Live Broadcast Events
4. Slow-motion video study shows shrews are highly sophisticated predators
5. Professors video series explains all facets of Earth
6. Videos extract mechanical properties of liquid-gel interfaces
7. Silex Introduces Worlds First Wireless USB Device Server With Streaming Video and Audio Data Transfer
8. Mosaic Intelligent Video Management System: Video Surveillance Just Got Smarter
9. Findings released from 1 of the largest percutaneous coronary intervention trials ever
10. Researchers discover natural herbicide released by grass
11. Upgraded IMG 2.3 Data Management System released by DOE JGI to eager user community
Post Your Comments:
(Date:10/29/2015)... Today, LifeBEAM , a leader ... a global leader in technical performance sports clothing ... advanced bio-sensing technology. The hat will allow fitness ... biometrics to improve overall training performance. As a ... bring together the most advanced technology, extensive understanding ...
(Date:10/27/2015)... 2015 Munich, Germany ... technology (ASGM) automatically maps data from mobile eye tracking ... , so that they can be quantitatively analyzed with ... Munich, Germany , October 28-29, 2015. SMI,s Automated ... mobile eye tracking videos created with SMI,s Eye ...
(Date:10/26/2015)... India , October 26, 2015 ... --> adds ... 2015 to 2021 as well as ... 2015-2019 research reports to its collection ... . --> ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... TapImmune, Inc. (TPIV), a ... peptide and gene-based immunotherapeutics and vaccines for the treatment ... be presenting at the 8 th Annual LD ... PM PT. Dr. John N. Bonfiglio a ... the presentation and will join TapImmune management in meeting ...
(Date:11/30/2015)...  AbbVie, is introducing Good Morning Hypothyroidism ... routine for managing the life-long condition of hypothyroidism. When ... way the body absorbs it so resources encouraging patients ... are important. The goal of the new website ... hypothyroidism by establishing a daily routine, spirit of connection, ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... with MarkLogic, the Enterprise NoSQL database platform provider, creating a seamless approach ... Smartlogic’s Content Intelligence capabilities provide a robust set of semantic tools which ...
(Date:11/27/2015)... , Nov. 27, 2015 /PRNewswire/--  Mallinckrodt plc ... announced today that it has closed the sale of ... to Guerbet (GBT- NYSE Euronext) in a transaction valued ... four manufacturing facilities and a total of approximately 1,000 ... the St. Louis area. This ...
Breaking Biology Technology: