Navigation Links
Vibrations influence the circadian clock of a fruit fly
Date:1/31/2014

The internal circadian clock of a Drosophila (fruit fly) can be synchronised using vibrations, according to research published today in the journal Science. The results suggest that an animal's own movements can influence its clock.

The circadian clock, which underlies the daily rhythms characterising most of our bodily functions including the sleep cycle, is mainly set by diurnal changes in light and temperature.

Researchers at UCL and Queen Mary, University of London, have now shown that exposure to 12-hour cycles of vibration and silence are also sufficient to synchronise the fly's internal clock, and corresponding daily locomotor activity.

"In a nutshell, our research shows that, in flies, the biological clock which regulates most bodily functions can be set or entrained not only by light and temperature, but also by mechanical stimuli that excite sensory receptors in the body," says Dr Joerg Albert (UCL Ear Institute), a senior author of the study.

"Our research encourages further research into the genetic and cellular basis of how the circadian clock is set," continues Dr Albert. "In mammals and humans there has been sporadic, but as yet inconclusive evidence to show if, and how, movement such as scheduled physical exercise can reset the clock."

Professor Ralf Stanewsky (Department of Cell and Developmental Biology, UCL; previously Queen Mary, University of London) another lead author of the study added: "Our experiments offer a novel pathway for setting the circadian clock that may well be relevant for the treatment of clock related diseases, such as insomnia, depression, bipolar disorder.

"It also offers a novel way to set the circadian clock using movement as well as extrinsic entrainment such as ambient light and temperature fluctuations. It could point to the existence of an animal's internal 'own time' that might have to be negotiated with the external 'world time'."


'/>"/>
Contact: David Weston
d.weston@ucl.ac.uk
44-020-310-83844
University College London
Source:Eurekalert

Page: 1

Related biology news :

1. Virtual vehicle vibrations
2. Discovery of quantum vibrations in microtubules corroborates theory of consciousness
3. Circadian rhythms have profound influence on metabolic output, UCI study reveals
4. BUSM researchers identify genes that influence hippocampal volume
5. Fat outside of arteries may influence onset of coronary artery disease
6. New evidence that many genes of small effect influence economic decisions and political attitudes
7. Predators have outsized influence over habitats
8. How an ancestral fungus may have influenced coal formation
9. New research questions how fat influences flavor perception
10. New model of disease contagion ranks US airports in terms of their spreading influence
11. Scientists identify new gene that influences survival in ALS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... The Department of Transport Management (DOTM) ... million US Dollar project, for the , Supply ... Enrolment, and IT Infrastructure , to ... implementation of Identity Management Solutions. Numerous renowned international vendors participated ... was selected for the most compliant and innovative ...
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
(Date:5/24/2016)... IRVINE, Calif. , May 24, 2016 Ampronix facilitates superior patient care ... LMD3251MT  3D medical LCD display is the latest premium product recently added to ... ... ... Sony 3d Imaging- LCD Medical Display- Ampronix News ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... MONICA, Calif. , June 23, 2016  The Prostate Cancer Foundation ... pioneer increasingly precise treatments and faster cures for prostate cancer. Members of the ... institutions across 15 countries. Read More About the Class ... ... ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... OTTAWA, ON (PRWEB) , ... June 23, 2016 , ... ... former DNA Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA ... joining the STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. ...
(Date:6/23/2016)... , June 23, 2016 Apellis Pharmaceuticals, ... 1 clinical trials of its complement C3 inhibitor, ... and multiple ascending dose studies designed to assess ... of subcutaneous injection in healthy adult volunteers. ... either as a single dose (ranging from 45 ...
Breaking Biology Technology: