Navigation Links
Viable and fertile fruit flies in the absence of histone H3.3
Date:11/13/2012

begin to develop from cells without H3.2 but these died in the first larval stage," Hdl continues.

Genes are switched on and off without histone modification

Histones are modified by different enzymes at different points in the protein. In a second experiment, Basler and Hdl examined the importance of modifications of the fourth amino acid of the protein, a lysine. Modification of this lysine is thought to play a key role in activating and deactivating the transcription of the gene. To test this, the scientists replaced the lysine with non-modifiable amino acids in all the histone H3 genes. The result was another big surprise. "Cells without this specific histone modification are able to divide normally," explains Basler before adding: "However, they do so considerably more slowly than cells that have not been modified." Therefore, the modification of this lysine is not essential for the activation of the genes.

The results show that the activation of genes and the inheritance of the ability to activate genes work differently than previously assumed. Clearly, the structure of the transcription process is extremely robust. According to Basler, the role of this common histone modification for cell function has been overestimated in recent years.


'/>"/>

Contact: Martina Hdl
martina.hoedl@imls.uzh.ch
41-446-353-115
University of Zurich
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Could chloroplast breakthrough unlock key to controlling fruit ripening in crops?
2. Bees, fruits and money
3. Fruity science halves fat in chocolate
4. Study of fruit fly chromosomes improves understanding of evolution and fertility
5. Hormone in fruit flies sheds light on diabetes cure, weight-loss drug for humans
6. Virginia Tech and University of Tuscia lead team to unravel origin of devastating kiwifruit bacterium
7. Fruit flies provide new knowledge about uninhibited cell growth
8. First fruitful, then futile: Ammonites or the boon and bane of many offspring
9. An invasive Asian fly is taking over European fruit
10. Evolutionary straitjacket means flies cant take the heat
11. Massachusetts butterflies move north as climate warms
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Viable and fertile fruit flies in the absence of histone H3.3
(Date:10/1/2014)... prairies and forests of the world can also be ... to a surprising new study led by Colorado State ... The research team analyzed 596 soil samples collected from ... diversity of below-ground life, most of which had never ... 16.2 percent of the organisms discovered in the park ...
(Date:9/30/2014)... the environmental effects of moorland burning is published today ... with the aim of relieving tensions on both sides ... EMBER (Effects of Moorland Burning on the Ecohydrology of ... moorland, which is practised predominantly to support red grouse ... peat hydrology, peat chemistry and physical properties, river water ...
(Date:9/30/2014)... something that we enjoy when we visit a national park ... of ourselves as a part of nature? A bird,s nest ... , The answers to these questions reflect different cultural ... and in cultural artifacts. , A new Northwestern University study, ... Center of Chicago and the Menominee tribe of Wisconsin, focuses ...
Breaking Biology News(10 mins):Microbes in Central Park soil: If they can make it there, they can make it anywhere 2Microbes in Central Park soil: If they can make it there, they can make it anywhere 3Grouse moor burning causes widespread environmental changes 2The cultural side of science communication 2
... and American researchers found the fossil remains of a whale, ... published, for the first time, the results of the decay ... young cetacean, possibly a baleen whale from the Mysticeti group. ... fossil remains of a whale from the Lower Pliocene (five ...
... consumers can look forward to ultra-low powered or self ... phones. This is made possible with power management and ... power optimisation and higher energy efficiency in electronic devices ... enabling capability for power management and energy harvesting. To ...
... The mouse is a standard laboratory model organism, ... techniques to analyze blood and blood-forming tissues in this ... easy-to-use laboratory resources from Cold Spring Harbor Laboratory Press ... step-by-step protocols for the preparation, enumeration, and microscopic examination ...
Cached Biology News:Story of 4.5 million-year-old whale unveiled in Huelva 2Story of 4.5 million-year-old whale unveiled in Huelva 3NTU and EDB launch S$50 million ($36 million) integrated circuit design research center 2NTU and EDB launch S$50 million ($36 million) integrated circuit design research center 3New source of classical techniques for blood-based studies in the laboratory mouse 2
(Date:10/1/2014)... BOSTON, MA (PRWEB) September 30, 2014 ... company, SoundConnect announces four new-hosted collaboration ... innovative bundles deliver high quality conferencing experiences for ... collaboration packages to choose from, businesses have optimized ... bundled solutions include audio only minutes ...
(Date:10/1/2014)... October 01, 2014 The U.S. Department ... Southern Illinois University Edwardsville as part of the Trade ... The funding is co-administered by the Department of Labor ... Secretary of Labor Thomas E. Perez and Secretary of ... in job-driven training grants to nearly 270 colleges across ...
(Date:9/30/2014)... release is available in German . ... around several quantum dots in a semiconductor layer. Quantum dots ... of atomic processes. If a short laser pulse is fired ... the quantum dot experiences a change in the electromagnetic field ... the emission of light by the dot. As soon as ...
(Date:9/30/2014)... bio-mimicking analog of one of nature,s most efficient ... team led by Alejandro Briseno of the University ... in developing long-sought polymer architecture to boost power-conversion ... electronic devices. , Briseno, with colleagues and ... Stanford University and Dresden University of Technology, Germany, ...
Breaking Biology Technology:SoundConnect Launches New Audio, Web and Video Bundles 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 3U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 4Ultrafast remote switching of light emission 2Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3
... Cellectis (Alternext: ALCLS), the French genome engineering specialist, ... (CiRA) of Kyoto University, Kyoto, Japan, have announced today ... Cellectis, genome engineering technologies with CiRA,s induced pluripotent stem ... iPS cells for use as cellular tools. ...
... Therapeutics, Inc. (Nasdaq: TSRX ) announced today that ... present "Innovative Antibacterial Drugs by Design; The Trius Therapeutics Story" ... October 26, 2010 from 5:30-9:30 p.m. PT. ... . About Trius Therapeutics ...
... International Holdings, Inc. (OTC Bulletin Board: ... medical applications and revolutionary bone graft material, today announced ... Wickwire, a distinguished Washington, D.C. based attorney and Michael ... Carparelli, to its Board of Directors.  Effective immediately, Mr. ...
Cached Biology Technology:Cellectis and the Center for iPS Cells Research and Application Enter Collaboration 2Cellectis and the Center for iPS Cells Research and Application Enter Collaboration 3Bacterin International Reconstitutes Its Board of Directors and Appoints Experienced Legal and Financial Professionals 2Bacterin International Reconstitutes Its Board of Directors and Appoints Experienced Legal and Financial Professionals 3Bacterin International Reconstitutes Its Board of Directors and Appoints Experienced Legal and Financial Professionals 4
Phospho- (Ser) 14-3-3 Binding Motif (4E2) Mouse mAb...
Rat polyclonal to acetyl Salicylic Acid ( Abpromise for all tested applications)....
Drugs and NO-drug Rat Anti-conjugated Acetyl Salicylic Acid Polyclonal Antibody...
Rabbit polyclonal to UBC12 (rating: ****) ( Abpromise for all tested applications). Antigen: Synthetic peptide: RGGYIGSTYFER, corresponding to amino acids 169-180 of UBC12 Entrez Gene ID: 90...
Biology Products: