Navigation Links
Vanderbilt ethicist to study return of results issue involving children in genomics studies
Date:9/28/2011

Answering the questions of if, when and how scientists should inform participants in genomic studies about their risk for diseases or conditions is the aim of new research funded with a $5.7 million grant to Ellen Wright Clayton, Craig-Weaver Professor of Pediatrics and director of the Center for Biomedical Ethics and Society at Vanderbilt University, and seven other experts.

"These new research projects will help us understand how people are reacting to real information about their genomes, which is an increasingly pressing issue as more scientists incorporate genome sequencing into their research," said Eric D. Green, director of the National Human Genome Research Institute which awarded the grants. "We're putting the best minds together to try to develop best practices on this issue by establishing a consortium of all the funded researchers."

The goal of Clayton's project is to identify criteria to guide decisions about returning individual research results to children who participate in genomic research. To do so, she will examine U.S. law and international guidelines about decision-making for and by minors. Then, she will analyze what weight should be given to various benefits potentially associated with returning pediatric research results. These range from immediate benefit to the minor's health or for the minor's reproductive decision-making later in life, to benefits to parents, the minor's siblings or the family as a whole.

Genomic researchers have widely varying opinions on the "return of results" issue. Some believe that they have an ethical or legal obligation to reveal genomic information to study participants -- especially if it is medically significant and treatments are available. Others consider sharing such information unethical -- particularly if the participant was told he or she would not be re-contacted, if the information relates to an untreatable disorder or if the significance of the information is unclear. There are also regulatory and policy issues related to developing clinical applications that the researchers must consider.

According to NHGRI, the studies they have commissioned will shed light on real-life applications of returning genomic results to study participants.


'/>"/>
Contact: David Salisbury
david.salisbury@vanderbilt.edu
61-534-336-803
Vanderbilt University
Source:Eurekalert  

Related biology news :

1. Vanderbilt researchers, international team, uncover genes linked to multiple sclerosis
2. Vanderbilt-Ingram Cancer Center launches online genetic research tool
3. Scripps Research and Vanderbilt to launch joint institute
4. Vanderbilt engineers play key role in new DOE energy frontier research center
5. Vanderbilt scientists invent worlds smallest periscopes
6. Utah ethicist heads stem cell panel
7. Wildlife Conservation Society study uncovers a predictable sequence toward coral reef collapse
8. US Forest Service study finds hemlock still abundant despite adelgid infestation
9. NIH-funded study connects gene variant to response to asthma drugs
10. Study puts a new spin on ibuprofens actions
11. University of Arizona to study human-fire-climate interactions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Vanderbilt ethicist to study return of results issue involving children in genomics studies
(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
(Date:5/12/2016)... 12, 2016 WearablesResearch.com , a brand ... overview results from the Q1 wave of its quarterly ... was consumers, receptivity to a program where they would ... health insurance company. "We were surprised to ... Michael LaColla , CEO of Troubadour Research, "primarily ...
(Date:4/28/2016)... 2016 First quarter 2016:   ... with the first quarter of 2015 The gross margin ... (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) , ... unchanged, SEK 7,000-8,500 M. The operating margin for 2016 ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...  Global demand for enzymes is forecast to ... $7.2 billion.  This market includes enzymes used in ... production, animal feed, and other markets) and specialty ... and beverages will remain the largest market for ... products containing enzymes in developing regions.  These and ...
(Date:6/27/2016)... ... , ... Parallel 6 , the leading software as a service (SaaS) ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication between ... Using the CONSULT module, patients and physicians can schedule a face to face virtual ...
(Date:6/27/2016)... , June 27, 2016   Ginkgo Bioworks , ... industrial engineering, was today awarded as one of ... of the world,s most innovative companies. Ginkgo Bioworks ... for the real world in the nutrition, health ... work directly with customers including Fortune 500 companies ...
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita ... miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject of ... now. , Diagnostic biomarkers are signposts in the blood, lung fluid or tissue ...
Breaking Biology Technology: