Navigation Links
Van Andel research institute study provides new details of fundamental cellular process

Grand Rapids, Mich. A recent Van Andel Research Institute (VARI) study published in the journal Science investigating the molecular structure and function of an essential plant hormone could profoundly change our understanding of a key cell process, and might ultimately lead to the development of new drugs for a variety of diseases.

The study builds on earlier work by the same team of investigators at VARI that was published in the journal Nature in 2009. That study shed light on how plants respond when they are under stress from extreme temperatures, drought and other harsh environmental conditions and was later named by Science as one of the top scientific breakthroughs of 2009.

The current research conducted on the plant hormone Abscisic acid (ABA) determined that during signal transduction the basic process of intercellular and intracellular communication certain enzymes mimic the structure of the opposing enzyme. This insight may enable scientists to more accurately develop mechanisms to activate or inhibit intercellular and intracellular communication, which could lead to the development of plants that more readily survive drought or other conditions of stress.

In mammalian cells the ability to impact communication has numerous and far-reaching implications. For example, applications that inhibit or activate cell communication in out-of-control metastasizing cancer cells have enormous potential to affect tumor growth.

"This type of finding once again demonstrates the importance of identifying, mapping and understanding fundamental cellular and molecular processes because of the profound implications for human health," said H. Eric Xu, Ph.D., Director of the VARI Center for Structural Biology and Drug Discovery and co-author of the current Science study.

Contact: Joe Gavan
Van Andel Research Institute

Page: 1

Related biology news :

1. TGen finalizes alliance with Van Andel Research Institute
2. Organic weed control for dandelions
3. American Society for Microbiology honors Jo Handelsman
4. Statement by Sandy Andelman, co-author of Drought sensitivity of the Amazon Rainforest
5. Van Andel Research Institute and TGen undertake alliance to promote science and health
6. SUNY Downstate receives grant from research to prevent blindness
7. Researchers develop gene therapy that could correct a common form of blindness
8. Researchers meet to refine carbon budget for US East Coast
9. Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research
10. Scripps Research scientists provide new understanding of chronic pain
11. Penn researchers help solve questions about Ethiopians high-altitude adaptations
Post Your Comments:
(Date:3/30/2017)... March 30, 2017 The research team of ... three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint minutiae ... realm of speed and accuracy for use in identification, crime investigation, ... cost. ... A research ...
(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
(Date:3/27/2017)... March 27, 2017  Catholic Health Services (CHS) ... Systems Society (HIMSS) Analytics for achieving Stage 6 ... sm . In addition, CHS previously earned a ... using an electronic medical record (EMR). ... level of EMR usage in an outpatient setting.  ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... SomaGenics announced the receipt of a Phase ... (Single Cell), expected to be the first commercially available ... from single cells using NGS methods. The NIH,s recent ... development of approaches to analyze the heterogeneity of cell ... for measuring levels of mRNAs in individual cells have ...
(Date:10/10/2017)... ... October 10, 2017 , ... The Pittcon Program Committee is ... honoring scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy. ... world’s leading conference and exposition for laboratory science, which will be held February ...
(Date:10/9/2017)... ... , ... The award-winning American Farmer television series will feature 3 Bar Biologics ... at 8:30aET on RFD-TV. , With global population estimates nearing ten billion people ... to feed a growing nation. At the same time, many of our valuable resources ...
(Date:10/9/2017)... ... 2017 , ... The Giving Tree Wellness Center announces the ... of consumers who are incorporating medical marijuana into their wellness and health regimens. ... operators of two successful Valley dispensaries, The Giving Tree’s two founders, Lilach Mazor ...
Breaking Biology Technology: