Navigation Links
Van Andel research institute study provides new details of fundamental cellular process
Date:1/23/2012

Grand Rapids, Mich. A recent Van Andel Research Institute (VARI) study published in the journal Science investigating the molecular structure and function of an essential plant hormone could profoundly change our understanding of a key cell process, and might ultimately lead to the development of new drugs for a variety of diseases.

The study builds on earlier work by the same team of investigators at VARI that was published in the journal Nature in 2009. That study shed light on how plants respond when they are under stress from extreme temperatures, drought and other harsh environmental conditions and was later named by Science as one of the top scientific breakthroughs of 2009.

The current research conducted on the plant hormone Abscisic acid (ABA) determined that during signal transduction the basic process of intercellular and intracellular communication certain enzymes mimic the structure of the opposing enzyme. This insight may enable scientists to more accurately develop mechanisms to activate or inhibit intercellular and intracellular communication, which could lead to the development of plants that more readily survive drought or other conditions of stress.

In mammalian cells the ability to impact communication has numerous and far-reaching implications. For example, applications that inhibit or activate cell communication in out-of-control metastasizing cancer cells have enormous potential to affect tumor growth.

"This type of finding once again demonstrates the importance of identifying, mapping and understanding fundamental cellular and molecular processes because of the profound implications for human health," said H. Eric Xu, Ph.D., Director of the VARI Center for Structural Biology and Drug Discovery and co-author of the current Science study.


'/>"/>
Contact: Joe Gavan
Joe.Gavan@vai.org
616-234-5390
Van Andel Research Institute
Source:Eurekalert

Page: 1

Related biology news :

1. TGen finalizes alliance with Van Andel Research Institute
2. Organic weed control for dandelions
3. American Society for Microbiology honors Jo Handelsman
4. Statement by Sandy Andelman, co-author of Drought sensitivity of the Amazon Rainforest
5. Van Andel Research Institute and TGen undertake alliance to promote science and health
6. SUNY Downstate receives grant from research to prevent blindness
7. Researchers develop gene therapy that could correct a common form of blindness
8. Researchers meet to refine carbon budget for US East Coast
9. Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research
10. Scripps Research scientists provide new understanding of chronic pain
11. Penn researchers help solve questions about Ethiopians high-altitude adaptations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... June 9, 2016 Paris ... Teleste,s video security solution to ensure the safety of people ... during the major tournament Teleste, an international ... and services, announced today that its video security solution will ... to back up public safety across the country. The system ...
(Date:6/3/2016)... Das DOTM (Department ... hat ein 44 Millionen $-Projekt ... einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an Decatur ... Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale Anbieter ... aber Decatur wurde als konformste und innovativste ...
(Date:6/2/2016)... , June 2, 2016   The Weather Company , ... Watson Ads, an industry-first capability in which consumers will be ... able to ask questions via voice or text and receive ... Marketers have long sought an advertising ... that can be personal, relevant and valuable; and can scale ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... , ... December 01, 2016 , ... ACEA Biosciences, Inc. ... Phase I/II clinical trials for AC0010 at the World Conference on Lung Cancer 2016, ... an update on the phase I/II clinical trials for AC0010 in patients with advanced ...
(Date:12/2/2016)... ... December 01, 2016 , ... The Conference Forum has announced that the ... will take place on February 1-3, 2017 at the Roosevelt Hotel in New York ... program provides a unique 360-degree approach, which addresses the most up-to-date information regarding business ...
(Date:12/2/2016)... ... December 02, 2016 , ... Robots will storm the ... on December 3rd, 2016. The event, which is held on the United Nations International ... Americans with Disabilities back into the workplace. Suitable Technologies is partnering with NTI to ...
(Date:11/30/2016)... ... November 30, 2016 , ... BEI Kimco, ... Actuator with a flexure design that ensures high alignment accuracy by preventing unwanted ... is ideally suited where extreme precision is required, such as in medical equipment, ...
Breaking Biology Technology: