Navigation Links
Vaccines preventing pneumococcal disease protect African children with sickle-cell disease
Date:4/28/2010

WASHINGTON, DC A new study released this week in The Lancet Infectious Diseases finds that African children who contract pneumococcus a bacterial infection that causes pneumonia, meningitis and sepsis are 36 times as likely to have sickle-cell disease, a blood disorder prevalent in African children that increases the risk for infectious diseases and early death. The study underscores the critical need for use of pneumococcal conjugate vaccines (PCV) among populations predisposed to sickle-cell disease, most notably those in sub-saharan Africa.

"Our findings clearly show that African children with sickle-cell disease are at increased risk of bacterial illness compared with their peers without sickle-cell disease, with the pneumococcus being of particular concern," said Dr. Keith P. Klugman, contributing author and professor and William H. Foege Chair in Global Health at the Rollins School of Public Health.

Africa is home to the vast majority of the world's sickle-cell disease cases. Sickle-cell disease is inherited by a child from both parents and is caused by abnormal hemoglobin, a blood protein that distorts the shape of red blood cells and delivers less oxygen to tissues. The disease weakens the immune system and puts its victims at risk for serious bacterial infection and childhood death. Data examined from studies in the Democratic Republic of the Congo, Nigeria, Kenya and Senegal countries with the highest sickle-cell disease burden clearly demonstrate an increased risk of serious bacterial infection, especially invasive pneumococcal disease, in African children with sickle-cell disease.

"In combination with early diagnosis and treatment of sickle-cell disease, routine, country-wide immunization against pneumococcus is the best strategy to improve quality of life for all African children, particularly those with sickle-cell disease," said Orin Levine, contributing author, executive director of the International Vacci
'/>"/>

Contact: Mala Persaud
Mala.Persaud@gmmb.com
202-572-2980
Johns Hopkins University Bloomberg School of Public Health
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. GEN reports on the promise of DNA vaccines
2. Major breakthrough may pave the way for therapeutic vaccines
3. Bug barcode readers hold out promise of universal vaccines
4. Pitt researchers find promising candidate protein for cancer prevention vaccines
5. Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma
6. Princeton teams analysis of flu virus could lead to better vaccines
7. New evidence explains poor infant immune response to certain vaccines, says MU researcher
8. Vaccines and autism: Many hypotheses, but no correlation
9. New type of vaccines deliver stronger and faster immune response
10. Syracuse University partners with Serum Institute of India to develop vaccines for children
11. Prostate cancer vaccines more effective with hormone therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... , Saturday to Wednesday, Oct. 18-22, 2014 , ... W. Harbor Drive, San Diego, CA 92101 , ... and other presentations of the latest research in ... plenary session featuring high-scoring abstracts on rare genetic ... various cancers, and treatment for sun sensitivity (Saturday, ...
(Date:8/21/2014)... A team of researchers at Louisiana Tech ... using affordable, consumer-grade 3D printers and materials ... contain antibacterial and chemotherapeutic compounds for targeted ... doctoral students and research faculty from Louisiana ... collaborated to create filament extruders that can ...
(Date:8/21/2014)... pancreatitis involves the pancreas digesting itself resulting in severe ... the UK around 20,000 patients are diagnosed with the ... cure and treatment is restricted to intravenous fluid and ... Faculty of Life Sciences, who led the research, said ... from gall stones and excessive alcohol intake combined with ...
Breaking Biology News(10 mins):American Society of Human Genetics 2014 Annual Meeting 2Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3Insulin offers new hope for the treatment of acute pancreatitis 2
... bacterium or virus starts rummaging through the contents of a ... host,s DNA strands, it can alter the host,s biological course. ... particular sequences of DNA, to bend, kink and twist the ... any part of a DNA strand, but these seemingly random ...
... , HOUSTON -- (Aug. 30, 2012) -- The threads of ... biology are beginning to unravel, thanks to a new investigation ... Texas MD Anderson Cancer Center. In new research published ... Oleg Igoshin and MD Anderson,s Christian Ray offer a possible ...
... Bacteria in hyenas, scent glands may be the ... the current issue of Scientific Reports , show ... and the distinct microbial communities that reside in their ... and Michigan State University postdoctoral researcher. "A critical ...
Cached Biology News:Biophysicists unravel secrets of genetic switch 2Biophysicists unravel secrets of genetic switch 3Rice, MD Anderson scientists probe mystery of operon evolution 2Rice, MD Anderson scientists probe mystery of operon evolution 3Rice, MD Anderson scientists probe mystery of operon evolution 4Microbes help hyenas communicate via scent 2
(Date:8/21/2014)... YORK , Aug. 21, 2014 ... congratulates Immune Pharmaceuticals Inc., a biotechnology company, on ... Market.  Immune previously traded on OTCQX®, the best ... by OTC Markets Group. Logo - ... Pharmaceuticals on the successful execution of its growth ...
(Date:8/21/2014)... Aug. 21, 2014  Four-dimensional (4-D) printing develops ... on external stimuli such as changes in temperature. ... disruptive effect in multiple industries.  In the near ... by printing objects ranging from human organs to ... Logo - http://photos.prnewswire.com/prnh/20140820/138289 ...
(Date:8/21/2014)... Bulgaria (PRWEB) August 21, 2014 ... released today by Ontotext . Now the ... semantic analysis of structured and unstructured data is available ... the cost of enterprise technology. Organizations that do not ... for data management can use S4 since there is ...
(Date:8/21/2014)... Boston, MA (PRWEB) August 21, 2014 ... collaboration company, has been recognized as one of ... 500 | 5000 magazine for the 2nd consecutive ... on its 33rd annual Inc. 500|5000, an exclusive ... list represents the most comprehensive look at the ...
Breaking Biology Technology:OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 4Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 3Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 4SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3
... , , ... , , , Duplications and ... different methods are used for detecting such rearrangements,most based on either ... accurate, but very labour intensive and expensive,while quantitative PCR methods are ...
... , ... , , , Slab ... the separated bands,of an unknown sample to a known,standard (size ... estimated. The Agilent,2100 bioanalyzer is an instrument,which utilizes LabChip,technology to ...
... , , ... , , , , Gene expression ... for analyzing cellular behavior in a micro,scale and is used in ... of RNA from specific cell,populations out of their surrounding tissue environment. ...
Cached Biology Technology:Rapid detection of genomic,duplications and deletions using,the Agilent 2100 bioanalyzer 2Rapid detection of genomic,duplications and deletions using,the Agilent 2100 bioanalyzer 3Rapid detection of genomic,duplications and deletions using,the Agilent 2100 bioanalyzer 4Rapid detection of genomic,duplications and deletions using,the Agilent 2100 bioanalyzer 5High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 2High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 3High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 4High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 5Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 2Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 3Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 4Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 5Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 6Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 7Quality assurance of RNA derived from,laser microdissected tissue samples,obtained by the PALM MicroBeam System,using the RNA 6000 Pico LabChip kit. 8
SH3 Proteins II Sampler Kit 10g each...
... reagent for Virus isolation ... unique water insoluble Elastomeric ... and chaotropes; Engineered to ... viruses while preserving infectivity; ...
Golgi Sampler Kit 10g each...
Caveolin Sampler Kit 10g each...
Biology Products: