Navigation Links
Vaccines and autism: Many hypotheses, but no correlation

An extensive new review summarizes the many studies refuting the claim of a link between vaccines and autism. The review, in the February 15, 2009 issue of Clinical Infectious Diseases and now available online, looks at the three main hypotheses and shows how epidemiological and biological studies refute these claims.

"When one hypothesis of how vaccines cause autism is refuted, another invariably springs up to take its place," said study author Paul Offit, MD, of the Children's Hospital of Philadelphia. Fears about vaccines are pushing down immunization rates and having a real impact on public health, he added. Vaccine refusal is contributing to the current increase in Haemophilus influenzae cases in Minnesotaincluding the death of one childand was a factor in last year's measles outbreak in California.

The controversy began with a 1998 study in The Lancet that suggested a link between the combination measles-mumps-rubella (MMR) vaccine and autism. Dr. Offit and co-author Jeffrey Gerber, MD, PhD, also of the Children's Hospital of Philadelphia, reviewed more than a dozen large studies, conducted in five different countries, that used different methods to address the issue, and concluded that no data supported the association between the MMR vaccine and autism. The correlation between MMR vaccine and the appearance of autism symptoms is merely coincidental, the authors say, because the MMR vaccine is given at the age when autism symptoms usually appear.

Also hypothesized as a cause has been the ethylmercury-containing preservative thimerosal, which was used in vaccines for over 50 years. However, the authors review seven studies from five countries that show that the presence or absence of thimerosal in vaccines did not affect autism rates.

The third suggestion has been that the simultaneous administration of multiple vaccines overwhelms or weakens the immune system. The authors explain that children's immune systems routinely handle much more than the relatively small amount of material contained in vaccines. Furthermore, today's vaccines contain many fewer immune-triggering components than those from decades past. Regardless, autism is not triggered by an immune response, the authors say.

With outbreaks of vaccine-preventable diseases on the rise due to some worried parents choosing not to vaccinate their children, Dr. Offit said, "Parents should realize that a choice not to get a vaccine is not a risk-free choice. It's just a choice to take a different, and far more serious, risk."


Contact: Steve Baragona
Infectious Diseases Society of America

Related biology news :

1. New type of vaccines deliver stronger and faster immune response
2. Syracuse University partners with Serum Institute of India to develop vaccines for children
3. Prostate cancer vaccines more effective with hormone therapy
4. From foe to friend: Researchers use salmonella as a way to administer vaccines in the body
5. VaxInnate to discuss seasonal and pandemic flu vaccines during BIO 2008 this week
6. Iowa State researchers look for smaller, cheaper, 1-dose vaccines
Post Your Comments:
(Date:6/30/2017)... Va. , June 30, 2017 ... leading developer and supplier of face and eye ... ATA Featured Product provider program. ... an innovative way to monitor a driver,s attentiveness ... greatly from being able to detect fatigue and ...
(Date:5/16/2017)...   Bridge Patient Portal , an enterprise ... EMR Systems , an electronic medical record solutions ... established a partnership to build an interface between ... Centricity™ products, including Centricity Practice Solution (CPS), Centricity ... new integrations will allow healthcare delivery networks using ...
(Date:4/17/2017)... MELBOURNE, Florida , April 17, 2017 ... security technology company, announces the filing of its 2016 Annual Report ... Securities and Exchange Commission. ... Report on Form 10-K is available in the Investor Relations section ... well as on the SEC,s website at . ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... , ... October 10, 2017 ... ... cancer-focused pharmaceutical company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing ... HPLN (Hybrid Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s ...
(Date:10/10/2017)... ... October 10, 2017 , ... USDM Life Sciences , ... life sciences and healthcare industries, announces a presentation by Subbu Viswanathan and Jennifer ... “Automating GxP Validation for Agile Cloud Platforms,” will present a revolutionary approach to ...
(Date:10/9/2017)... (PRWEB) , ... October 09, 2017 , ... ... a four-tiered line of medical marijuana products targeting the needs of consumers who ... packaging of Kindred takes place in Phoenix, Arizona. , As operators of two ...
(Date:10/6/2017)... ... October 06, 2017 , ... The HealthTech Venture Network (HTVN) ... their fourth annual Conference where founders, investors, innovative practitioners and collaborators are invited ... competition showcasing early stage digital health and med tech companies. , This day-long ...
Breaking Biology Technology: