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Using novel tool, UD researchers dig through cell 'trash' and find treasure
Date:9/19/2008

arge scale, identifying millions of molecules without bias and with a substantial reduction in labor and efforts."

The "holistic" technique will enable scientists to examine several regulatory pathways at once for a given stimulus versus just one, discovering novel networks of interactions, according to German.

"You could profile a mutant cell against a normal one and determine exactly what is happening and what enzymes are affected in decay processes," German said.

"The focus is changing," he noted. "Work that used to take months, you can now do in a week."

Currently, German is documenting an even faster method.

Originally from Argentina, German received his Ph.D. from the Hebrew University of Jerusalem, Israel. He was attracted to UD by the cell biology research being led by Green and Meyers, who have made internationally recognized strides in plant genetics, including studies of rice, the world's top grain.

"I like to develop new things--to explore and discover. That is the most rewarding thing of all about being a scientist," German said.

"The success rate in experiments like this is only 5 to 10 percent, but when you succeed, it's good," he added, smiling.


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Contact: Tracey Bryant
tbryant@udel.edu
302-831-8185
University of Delaware
Source:Eurekalert  

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Using novel tool, UD researchers dig through cell 'trash' and find treasure
Using novel tool, UD researchers dig through cell 'trash' and find treasure
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