Navigation Links
Using novel tool, UD researchers dig through cell 'trash' and find treasure
Date:9/19/2008

A person's trash can reveal valuable information, as detectives, historians and identity thieves well know. Likewise, a cell's "trash" may yield certain treasures, University of Delaware researchers have found.

Using a new technique they developed, scientists at UD's Delaware Biotechnology Institute analyzed the cellular waste of one of the world's most-studied plants and discovered formerly hidden relationships between genes and the small molecules that can turn them off.

The approach, devised by postdoctoral researcher Marcelo German, with Pamela Green, the Crawford H. Greenewalt Endowed Chair in Plant Molecular Biology, and Blake Meyers, associate professor of plant and soil sciences, and their research teams, is reported in the prestigious scientific journal Nature Biotechnology. It also is highlighted, along with two related techniques that were developed almost simultaneously by other U.S. research teams, in a commentary in the journal's "News and Views" by molecular biologists Ian Henderson and Steven Jacobsen from the University of California at Los Angeles.

The study, which was funded by the Department of Energy and the National Science Foundation, was undertaken in Arabidopsis thaliana, a member of the mustard family. The first flowering plant to have had all of its genetic material ("genome") sequenced, Arabidopsis is regarded as the botanical equivalent of the fruit fly due to the relatively small size of its genome and the ease with which the plant can be cultured and grown in the lab.

The researchers' focus was the cellular targets of tiny molecules of ribonucleic acid (RNA) known as "microRNAs," which play a critical role in how a plant cell develops and responds to stress. MicroRNAs bind to messenger RNAs, which are longer molecules that carry instructions to the cells to make proteins.

"The microRNAs target messenger RNAs--they are out to destroy them--in plant cells," Meyers said.


'/>"/>
Contact: Tracey Bryant
tbryant@udel.edu
302-831-8185
University of Delaware
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
2. Fever causing headaches for Aussie parents
3. Using evolution, UW team creates a template for many new therapeutic agents
4. Using green chemistry to deliver cutting-edge drugs
5. IGERT fellows to design biodevices using flexible electronics
6. Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
7. Computer program traces ancestry using anonymous DNA samples
8. Using nanotubes to detect and repair cracks in aircraft wings, other structures
9. Book on weeds and invasive plants discusses how to manage them using ecological approaches
10. Study shows housing development on the rise near national forests
11. Rare cancer-causing syndrome found, for the first time, in Singapore
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Using novel tool, UD researchers dig through cell 'trash' and find treasure
Using novel tool, UD researchers dig through cell 'trash' and find treasure
(Date:1/8/2009)... researchers at the UC Davis M.I.N.D. Institute ha...the number children born in California with autism...in how the condition is diagnosed or counted and ...in the January 2009 issue of the journal Epidemio...search should shift from genetics to the host of c...
(Date:1/8/2009)...panish . , Sludge obtained from water purifi...ls, for example or to reduce their acidity. The ma...PV/EHU) PhD research thesis was to study the effec...de Aguas Residuales - Waste Water Purification Pla... soil and on the water filtering through it with ...
(Date:1/7/2009)...ng repeat cesarean deliveries and having them at t...p to two times more likely to have a baby with ser...resulting in mechanical ventilation and NICU admis....D., Ph.D., assistant professor in the UAB Departm...nal-Fetal Medicine, and colleagues reported in a s...
(Date:1/7/2009)... A special issue of American Journal of Medical G... presents a comprehensive overview of the latest p...yperactivity Disorder (ADHD). The issue covers maj...tics, underscoring how genetic studies of ADHD hav...er its genetic origins. , ADHD is a complex cond...
Breaking Biology News(10 mins):Study shows California's autism increase not due to better counting, diagnosis 2Study shows California's autism increase not due to better counting, diagnosis 3Adding high doses of sludge to neutralize soil acidity not advisable 2Repeat C-section before 39 weeks raises risk of neonatal illness 2Studies examine genetic determinants of ADHD 2A new way to look at lung cancer and tobacco carcinogens 20431 1A new way to look at lung cancer and tobacco carcinogens 20431 2PBM Companies Partner with the Red Cross to Donate Infant Formula to China Earthquake Victims 20426 1PBM Companies Partner with the Red Cross to Donate Infant Formula to China Earthquake Victims 20426 2Hill Rom Announces Third Quarter 2008 Dividend 20421 1C Sections Explain Jump in U S Preemie Births 20417 1C Sections Explain Jump in U S Preemie Births 20417 2C Sections Explain Jump in U S Preemie Births 20417 3
... question for so many human interactions and perso...larger role than nurture when it comes to family r.... , Researchers from the University of Texas at Au...n, D.C., used data on 674 families, each with a sa...at made up the relationships and individual person...
...mors release fatty acids that interfere with the c...trategies that reduce the amount of fatty acids su...er therapeutics. The details of these findings app... Research, an American Society for Biochemistry an...ti-cancer therapy rely on what is known as immunot...
...by Professor Ian Day and colleagues at the Univers...on healthcare in the future. , One of two gene mut... and his team in the Human Genetics Division of th...fully applied to search for rare genetic mutations...ed meltMADGE, which combines thermal ramp electrop...
...lating cell volume says Dutch researcher Bas Tomas...ater by the plasma membrane of animal and human ce...ance between water uptake and secretion by the cel...by adjusting the salt concentrations in and around... not known. Bas Tomassen has identified a number o...
Other Biology News:Environment, not genes, key in family relationships 2Researchers discover new tumor defense system 2New gene scanning technology marks a major advance in disease research 2Water management in cells 2
(Date:1/8/2009)... Concentric Medical, Inc., the glo... stroke patients, today announced that it has comp... was led by leading venture capital firm New Enter...isting investors and new investors. , , "The po...veral months made the opportunity to participate i...
(Date:1/8/2009)...swire-FirstCall/ -- Amicus Therapeutics (Nasdaq: ...er, Ph.D., to its Board of Directors. Dr. Barer c...ficer of Celgene Corporation. As an industry vete...experience and a reputation as a trusted and respe...one of the world,s preeminent biopharmaceutical co...
(Date:1/8/2009)...ernational Conference on Health Informatics (HEALT...orkshop titled "Open Source in European Healt... Porto, Portugal (PRWEB) January 8, 2009 --...op of the upcoming International Conference on Hea...09 in Porto, Portugal. The workshop, titled "...
(Date:1/7/2009)...08 Researchers from Harvard University and the Na...or the first time, a repulsive quantum mechanical ...ide range of new nanotechnology applications. , ...ace Professor of Applied Physics at Harvard,s Scho... be published as the January 8 cover story of Nat...
Breaking Biology Technology:Concentric Medical Closes on $15 Million Financing 2Amicus Therapeutics Adds Sol J. Barer, Ph.D. to Board of Directors 2OpenClinica to Present at International Conference on Health Informatics, January 14-17, Porto, Portugal 2Researchers measure elusive repulsive force from quantum fluctuations 2
...dison Development Corp ., a non-profit development... $200,000 in venture capital to two Dane County te...loans in that amount to C5-6 Technologies, Inc., a...System Development , a past winner of the Governor...ich will develop enzymes used to improve the effic...
...is the sixth in a series of articles on developing...logy sectors. The most recent article focused on f...Now you have formed an entity. As part of the deci...ave concerned yourself with taxes. , ,The income t...axes depend upon the type of entity you form. If t...
... Rice, who has served as president and CEO of the ...for the past year, will leave ITAWi after an agree... telecommunications industry, the organization ann...search for Rice,s successor, and Chairman William ...lacement is found. Rice will remain on the ITAWi b...
...VC friend of mine (that had worked previously at a...cept that was gathering force - the deconstructio...eaning the casting away of parts and downsizing. ,..., I didn,t recognize this movement as the transfor...ecognized by a recent article in The Economist ,...
Other Biology Technology:Early Stage: Step 6 - Taxes, taxes, taxes! 2Early Stage: Step 6 - Taxes, taxes, taxes! 3Early Stage: Step 6 - Taxes, taxes, taxes! 4Rice to leave Wisconsin technology association 2The deconstruction of Big Pharma 2The deconstruction of Big Pharma 3The deconstruction of Big Pharma 4The deconstruction of Big Pharma 5The deconstruction of Big Pharma 6The deconstruction of Big Pharma 7The deconstruction of Big Pharma 8
...tandard for automated bioresearch: Developed for a...ased on decades of experience in Luminescence Spec... bioresearch • Holographic gratings for reduc... ease-of-use • Pulsed Xenon lamp reduces phot...
...the complete enterprise microarray informatics pla...and data analysis. Buy Acuity once and use it fore...s Tools for Quality Acuity has all the analysis t... quality control statistics and normalization, all...
...late 96/384 workstation offers precise 96 and 384-... Utilizing 100ul and 200ul disposable tips, the 96...t accuracy and precision across a volume range fro...two positions that enable indexing into 384 well p...
...nal-sized Thermal Cycler is the ideal instrument f...ll range of PCR applications. Get Applied Biosys.... Save lab space without sacrificing results. ...dustry-Standard PCR Technology You Can Afford Th...
Biology Products: