Navigation Links
Using morphine after abdominal surgery may prolong pain, CU-Boulder researchers find
Date:11/12/2013

ed with morphine for a week after the surgery took four weeks to recover from the postoperative pain compared with two weeks among the control group of rats.

"We're seeing the pain prolong for weeks after the discontinuation of morphine," Grace said.

The research team also tested the effects of the drug (+)-naloxone, which inhibits morphine from binding to the glial cells and exciting them. They found that the use of (+)-naloxone along with the morphine eliminated the extended postoperative pain effect.

The researchers are now studying in more detail how morphine excites glial cells and how (+)-naloxone works to block that process. A better understanding of that pathway in the brain may help researchers find a wider variety of drugs that could be administered along with morphine in the future to limit postoperative pain.


'/>"/>

Contact: Peter Grace
Peter.Grace@colorado.edu
University of Colorado at Boulder
Source:Eurekalert

Page: 1 2

Related biology news :

1. Studies reveal structure of EV71, a virus causing childhood illnesses
2. BYU study: Using a gun in bear encounters doesnt make you safer
3. The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
4. Beyond the microscope: Identifying specific cancers using molecular analysis
5. Cell therapy using patients own bone marrow may present option for heart disease
6. Using cell phones to detect harmful airborne substances
7. Disarming disease-causing bacteria
8. Notre Dame researchers using novel method to combat malaria drug resistance
9. High-resolution atomic imaging of specimens in liquid by TEM using graphene liquid cell
10. What is really causing the child obesity epidemic?
11. Better housing conditions for zebrafish could improve research results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... which life arose have been maintained in our cells today ... Research published today in the Journal of Biological Chemistry ... also in animals still perform ancient reactions thought to have ... billion years ago. , The primordial soup theory suggests that ... of the combination of metals, gases from the atmosphere and ...
(Date:7/24/2014)... . , Electric cars ... common sight on the roads of the Scandinavian country ... new vehicle registrations for the second time. This poses a ... claim only a small portion of the market. Of the ... mere 8000 are electric powered. The main factors discouraging motorists ...
(Date:7/23/2014)... SAN DIEGO , July 24, 2014 Pfenex ... initial public offering of 8,333,333 shares of its common stock ... In addition, Pfenex has granted the underwriters a 30-day option ... at the initial public offering price. The shares are expected ... 2014, under the symbol "PFNX". William Blair ...
Breaking Biology News(10 mins):Nano-supercapacitors for electric cars 2Nano-supercapacitors for electric cars 3Pfenex Inc. Announces Pricing Of Initial Public Offering 2
... cell biology and showing off the powers of new ... Golgi apparatus, which sorts newly synthesized proteins for transport ... during cell division, according to research to be presented ... Cell Biology (ASCB) annual meeting in New Orleans. ...
... the year,s end-of-life refrigerators, TVs, mobile phones, computers, monitors, ... cord worldwide could fill a line of 40-ton trucks ... Equator. That forecast, based on data compiled by ... of UN organizations, industry, governments, non-government and science organizations ...
... that present-day organisms evolved from earlier life forms. ... enzymes that help complete chemical processessuch as converting food ... Now a University of Iowa researcher and his colleagues ... "dihydrofolate reductase" as it occurred from bacteria to humans. ...
Cached Biology News:High-resolution 3-D imaging draws new picture of Golgi's whereabouts during cell division 2World e-waste map reveals national volumes, international flows 2World e-waste map reveals national volumes, international flows 3World e-waste map reveals national volumes, international flows 4World e-waste map reveals national volumes, international flows 5UI researcher studies evolution on the molecular level 2
(Date:7/24/2014)... 24, 2014  Neogen Corporation (Nasdaq: NEOG ... its potential revenue from new rodenticide research are premature. ... analysts on July 22, 2014, Neogen,s CEO commented about ... research. "It was my intent Tuesday at ... of a new type of rodenticide, but certainly not ...
(Date:7/24/2014)... The first part of the session ... in Human Studies” will cover comprehensive clinical support in ... With increasing R&D costs and declining industry success in ... the knowledge collected in early Phase I/IIa study data ... late stage development. , Next, the presenters will examine ...
(Date:7/24/2014)... , July 24, 2014   Cypher Genomics, ... the appointment of Adam Simpson as ... provides rapid and comprehensive annotation and interpretation of ... reporting. "Cypher,s technology has the potential ... by enhancing diagnostic accuracy, optimizing therapeutic approaches and ...
(Date:7/23/2014)... 24, 2014 Lyfebulb, the International Pemphigus ... and NASDAQ OMX First North Premier, ... announced a collaboration to increase awareness of unmet ... an event attended by more than sixty patients, ... a health and wellness company dedicated to serving ...
Breaking Biology Technology:Neogen comments on SenesTech 2Best Practices for Optimizing Dose Escalation in First in Human Studies, New Webinar August 6th Hosted by Xtalks 2Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 2Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 2Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 3Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 4Innovative Collaboration To Increase Awareness Of Bullous Pemphigoid, A Rare Autoimmune Disease Of The Skin 5
... 22, 2012 /PRNewswire-iReach/ -- FirstMark, the diagnostic ... that the company will be exhibiting at the 61st ... of Cardiology (ACC) in Chicago, March 24-27, Booth #15084. ... is the first and only multiple biomarker blood test ...
... The new Dynaflow Resolve System was developed in close ... demand for a simpler technology capable of complex perfusion ... perfusion system that enables novel experimental protocols by allowing ... type, and any compound. The new and improved system ...
... March 21, 2012 AtheroNova Inc. (OTCBB: AHRO), a ... compounds to regress atherosclerotic plaque, today announced that it ... development stage company, no revenues were recognized in the ... were $2,560,235 for 2011 compared to $2,679,435 in 2010. ...
Cached Biology Technology:FirstMark Exhibiting at the American College of Cardiology 61st Annual Scientific Sessions & Expo 2Cellectricon Launches Dynaflow® Resolve System Enabling Novel Ion Channel Assays 2AtheroNova Releases 2011 Financial Results 2AtheroNova Releases 2011 Financial Results 3
... DNA Engine Dyad instrument is the most ... Featuring MJ's world-class thermal performance, the Dyad ... as well as point-and-click navigation via touch ... can be easily and economically expanded to ...
...
Practical tool for easy, effective sealing of 0.2ml PCR tubes and plates using cap strips....
... RT Telomerase Detection Kit is ... assay for the fluorometric detection ... telomerase activity. It incorporates refinements ... and adds the ability to ...
Biology Products: