Navigation Links
Using modern sequencing techniques to study ancient modern humans
Date:12/31/2009

DNA that is left in the remains of long-dead plants, animals, or humans allows a direct look into the history of evolution. So far, studies of this kind on ancestral members of our own species have been hampered by scientists' inability to distinguish the ancient DNA from modern-day human DNA contamination. Now, research by Svante Pbo from The Max-Planck Institute for Evolutionary Anthropology in Leipzig, published online on December 31st in Current Biology a Cell Press publication overcomes this hurdle and shows how it is possible to directly analyze DNA from a member of our own species who lived around 30,000 years ago.

DNA the hereditary material contained in the nuclei and mitochondria of all body cells is a hardy molecule and can persist, conditions permitting, for several tens of thousands of years. Such ancient DNA provides scientists with unique possibilities to directly glimpse into the genetic make-up of organisms that have long since vanished from the Earth. Using ancient DNA extracted from bones, the biology of extinct animals, such as mammoths, as well as of ancient humans, such as the Neanderthals, has been successfully studied in recent years.

The ancient DNA approach could not be easily applied to ancient members of our own species. This is because the ancient DNA fragments are multiplied with special molecular probes that target certain DNA sequences. These probes, however, cannot distinguish whether the DNA they recognize comes from the ancient human sample or was introduced much later, for instance by the archaeologists who handled the bones. Thus, conclusions about the genetic make-up of ancient humans of our own species were fraught with uncertainty.

Using the remains of humans that lived in Russia about 30,000 years ago, Pbo and his colleagues now make use of the latest DNA sequencing (i.e., reading the sequence of bases that make up the DNA strands) techniques to overcome this problem. These technique
'/>"/>

Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Source:Eurekalert

Page: 1 2

Related biology news :

1. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
2. Fever causing headaches for Aussie parents
3. Using evolution, UW team creates a template for many new therapeutic agents
4. Using green chemistry to deliver cutting-edge drugs
5. IGERT fellows to design biodevices using flexible electronics
6. Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
7. Computer program traces ancestry using anonymous DNA samples
8. Using nanotubes to detect and repair cracks in aircraft wings, other structures
9. Book on weeds and invasive plants discusses how to manage them using ecological approaches
10. Study shows housing development on the rise near national forests
11. Rare cancer-causing syndrome found, for the first time, in Singapore
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/13/2015)... a leading cloud-based consumer engagement platform that provides trusted ... communities around health and wellness, announced today the launching ... The ... vehicle to receive validated health information from consumers. ... will allow higi,s trusted partners, on a user opt-in ...
(Date:4/8/2015)... April 8, 2015  Infinisource, a leading provider ... and Morpho, a leading supplier of biometric identification ... the market,s most advanced biometrically-enabled time clock, the ... time clock is setting a bold, new standard ... for the small and mid-size employer. When connected ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3
... Gladstone Institutes of Cardiovascular Disease (GICD) have found that ... the body is also an element in healthy skin ... 1 or DGAT1. Mice that lack DGAT1 have many ... diet-induced obesity, are more sensitive to insulin and leptin, ...
... release is available in German . , ... the 2009 Charles Rodolphe Brupbacher Prize for Cancer Research. Nubia ... tumours such as cervical cancer through human papilloma viruses and ... smoking. The prize from the Charles Rodolphe Brupbacher Foundation has ...
... This release is available in French and ... Granada , the Spanish National Research Council (CSIC) and the ... nacre,s growing mechanism of gastropods, a previous step for the ... possible its use in biomedicine, with applications such as the ...
Cached Biology News:Brupbacher prize to Nubia Munoz and Sir Richard Peto 2Brupbacher prize to Nubia Munoz and Sir Richard Peto 3A research work on molluscs nacre opens new doors for its possible use in biomedicine 2
(Date:5/5/2015)... 05, 2015 A comment period was ... range of key photonics technologies – regulations that some ... U.S. industry. To help the community understand and comment, ... on the proposed changes to U.S. Munitions List ... International Traffic in Arms Regulations (ITAR). , For the ...
(Date:5/5/2015)... , May 5, 2015 CytomX, a ... cancer, today announced that Sean McCarthy , D. ... Suisse Antibody Day in New York ... Dr. McCarthy will present an overview of CytomX,s Probody ... drug conjugate programs. About CytomX Therapeutics ...
(Date:5/5/2015)... 2015 GEA Pharma Systems, G-CON ... recipients of the INTERPHEX Exhibitor Awards for 2015 ... Portable, Continuous, Miniature and Modular (PCMM) platform. PCMM ... continuous processing equipment, smart control systems and PODs ... and inactive ingredients into bulk tablets. , ...
(Date:5/4/2015)... Many of us take a healthy ... with rare, inherited mutations of certain genes, severe ... impaired immune responses. Now, researchers at ... role for calcium signaling in immune responses to ... causing tuberculosis (TB). Specifically, they ...
Breaking Biology Technology:Comments needed now from photonics industry on revisions of U.S. export rules 2Comments needed now from photonics industry on revisions of U.S. export rules 3Comments needed now from photonics industry on revisions of U.S. export rules 4GEA Pharma Systems, G-CON Manufacturing and Pfizer Consortium Receives Best Technology Innovation Award at INTERPHEX 2015 2GEA Pharma Systems, G-CON Manufacturing and Pfizer Consortium Receives Best Technology Innovation Award at INTERPHEX 2015 3Researchers Discover A Novel And Unexpected Role For Calcium In Controlling Inflammation During Chronic Lung Infection 2Researchers Discover A Novel And Unexpected Role For Calcium In Controlling Inflammation During Chronic Lung Infection 3
... Inc., a privately held molecular diagnostics company developing innovative ... announced today the appointment of Peter Blume-Jensen, M.D., Ph.D. ... Metamark with over 20 years of experience in cancer ... Dr. Blume-Jensen was department head at EMD Serono, Inc. ...
... 16 Cord Blood America, Inc . ( ... the umbilical cord blood stem cell preservation company ... stem cells, a biological insurance policy, to families nationwide ... and CEO, was interviewed by analyst Francis Gaskins on ...
... LOUIS, Sept. 15 Sigma-Aldrich Corporation (Nasdaq: SIAL ... Healthcare Conference on Tuesday, September 21st at 12:30 PM ET ... audio broadcast over the Internet available at http://investor.sigmaaldrich.com/ . ... About Sigma-Aldrich: Sigma-Aldrich is ...
Cached Biology Technology:Metamark Genetics, Inc. Announces New Chief Scientific Officer 2Cord Blood America CEO Matthew Schissler Discusses Projects in China, South America, 'Afford-A-Cord,' and Profitability 2
Synaptotagmin, phosphoSer309...
Mouse anti-hepatitis delta virus Class: Antibody Product Group: Bacterial and Viral Antigen...
Mouse monoclonal [YLI-90] to Ly49I (Biotin) ( Abpromise for all tested applications)....
Rabbit polyclonal to KIAA1276 ( Abpromise for all tested applications). entrezGeneID: 27146 SwissProtID: Q9ULE4...
Biology Products: