Navigation Links
Using hair to manage HIV/AIDS and predict treatment success
Date:3/3/2009

HIV clinical care of measuring hemoglobin A1C, the method used in diabetes to monitor average blood glucose levels," said study co-investigator, Ruth M. Greenblatt, MD, UCSF professor of clinical pharmacy and principal investigator of the Women's Interagency HIV study.

Researchers took 10 strands of hair from patients on HIV therapy from the back of the head. They cut the hair sample close to the scalp underneath the top layer of hair, marked the part farthest from the scalp with tape and wrapped the strands in aluminum foil. The sample was then stored at room temperature in a plastic bag until it was analyzed.

"This is a painless, bloodless, biohazard-free, method of collecting a stable specimen from HIV patients that may allow for the monitoring of levels of antiretroviral drugs absorbed over time and the prediction of treatment success," said Gandhi. "Our next step is to test this method in resource-limited settings where blood collection and viral load monitoring may be expensive and difficult. Not only could this method help in measuring pill-taking, but its strong correlation with viral suppression could allow its use as an inexpensive, non-invasive method of monitoring treatment success in particularly challenging settings."

Researchers from this group are also collaborating with public health researchers in testing hair to monitor pill-taking in clinical trials of single or dual antiretrovirals in high risk, HIV negative individuals to prevent infection with HIV (pre-exposure prophylaxis, known as PrEP, trials).

The 224 patients in this study were drawn from the Women's Interagency HIV study, an ongoing multi-center, prospective study of HIV-infected and at risk uninfected women established in 1994.

"Women taking antiretroviral medications may have more adverse events than men taking these regimens. The safety trials of these medications were conducted in trials consisting largely of men, and the highest tole
'/>"/>

Contact: Jeff Sheehy
jsheehy@ari.ucsf.edu
415-597-8165
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Milestone achieved toward production of malaria treatment using synthetic biology and fermentation
2. MIT: Using touch to help deaf people
3. Dana-Farber oncologists present at ASCO GU -- predict prostate cancer survival using Source MDx test
4. Biological control of tropical weeds using arthropods
5. Defying the disaster: Researcher explores resilient housing
6. Link between unexploded munitions in oceans and cancer-causing toxins determined
7. Singapore research organisations team up to advance drug discovery using brain tumor stem cells
8. While focusing on heart disease, researchers discover new tactic against fatal muscular dystrophy
9. Mayo Clinic researchers suspect a novel gene is causing restless legs syndrome in a large family
10. Cancer-causing gene discovery suggests new therapies
11. Warmer climate causing huge increase in tree mortality across the West
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... CITY (July 28, 2014)The Brain & Behavior Research ... Klerman and Freedman Prizes, recognizing exceptional clinical and ... supported by NARSAD Young Investigator Grants. The grants ... in neurobiological and psychosocial research for the prevention, ... that affect one in four people. , Six ...
(Date:7/28/2014)... Research and Markets has announced ... America 2014-2018" report to their offering. ... and analyze biological data. These systems capture biological traits ... patterns, and hand measurements from the subject and compare ... main purpose of a biometrics system is to identify ...
(Date:7/28/2014)... from fertility problems, many of these due to genetic ... expect such genes, which reduce an individual,s ability to ... Weizmann Institute of Science that recently appeared in ... Not only can it explain the high rates of ... understanding the causes of genetic diseases and their treatment. ...
Breaking Biology News(10 mins):The Brain & Behavior Research Foundation names winners of Klerman and Freedman Prizes 2The Brain & Behavior Research Foundation names winners of Klerman and Freedman Prizes 3The Brain & Behavior Research Foundation names winners of Klerman and Freedman Prizes 4Biometrics Market in Latin America 2014-2018 2Mutations from Venus, mutations from Mars 2
... has evolved a unique technique for sensing motion may inspire ... active sonar. Although members of the fish ... environment and the movement of water around them with gel-covered ... underwater objects and navigate through their lightless environment inspired a ...
... a traffic accident with personal injury is significantly higher ... use of codeine alone does not carry an increased ... Norwegian Institute of Public Health. Codeine and ... mild to moderate pain. In Norway, codeine is included ...
... 2009 / b3c newswire / -  LabRoots Inc. ... social networking site for the scientific community. Beginning today, ... to LabRoots.com to begin building relationships with other scientists ... from giving scientists a place to share their expertise ...
Cached Biology News:Researchers develop flow sensors based on hair structures of blind cavefish 2Researchers develop flow sensors based on hair structures of blind cavefish 3Codeine use and accident risk 2LabRoots Launches Social Networking Site for Scientists & Engineers 2
(Date:7/28/2014)... 2014 Appistry, Inc. , a ... the power of genomics to next-generation medicine, announced today ... Challenge . , Two Appistry staff will be ... Center for Genome Resources, and Mr. Neil Miller, director ... Kansas City. Rounding out the panel are Appistry’s Dr. ...
(Date:7/28/2014)... COLLEGE STATION, Texas , July 28, 2014 /PRNewswire/ ... will be a 177-key, 4-star boutique hotel in the heart ... , Texas.  Photo - http://photos.prnewswire.com/prnh/20140725/130455 ... the first hotel within ATLAS , The ... mixture of standard rooms and suites, a sleek restaurant and bar, ...
(Date:7/25/2014)... "Ischemic Stroke and Cerebral Stroke ... on the Ischemic Stroke and Cerebral Stroke clinical ... data relating to the clinical trials on Ischemic ... Ischemic Stroke Research Report 2014 at: http://www.marketresearchreports.biz/analysis/213207 ... trial numbers and their recruitment status as per ...
(Date:7/25/2014)... -- Research and Markets  has announced the ... report to their offering. ... Metabonomics is the scientific study of chemical processes ... technique that is being widely used in biology, ... molecules that are present in blood, urine, and ...
Breaking Biology Technology:Appistry Names Industry Experts from the National Center for Genome Resources and Mercy Children's, Kansas City, to Judge Pipeline Challenge Competition 2Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 2Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 3Texas' Biocorridor Announces the Atlas Hotel, Centerpiece of Mixed Use Community for Biotech Industry 4Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 2Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 3Global Metabolomics Market 2014-2018: Key Vendors are Agilent, Bio-Rad, Bruker, Human Metabolome and Metabolon 2
... of Health, The Infectious Disease Research, Institute and ... of Advisors, SEATTLE, Oct. 7 The ... acquisition of compounds for further,development into tuberculosis (TB) ... SUMM) of Oxfordshire, UK, and the Microbial Chemistry,Research ...
... Oct. 7 BioEnergy International, LLC,(BioEnergy), a ... biochemicals and biofuels, announces the,addition of Norman ... effective December,2008. Mr. Augustine has a record ... level of industry and government culminating in ...
... Oct. 7 Morria Biopharmaceuticals Plc, ... of novel,anti-inflammatory drugs, announced today the ... novel anti-inflammatory drugs using MD Biosciences,Immunoprofiler(TM) ... was specifically,chosen to identify and assess ...
Cached Biology Technology:Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 2Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 3Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 4Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 5BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 2BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 3Morria Biopharmaceuticals Plc Announces Results From its Pre-Clinical Screening of Novel Anti-Inflammatory Compounds 2
... Systems provide fast and reliable automation ... and drug development laboratories. Staccato Custom ... specifications, providing solutions that are tailored ... Custom Systems are controlled with either ...
... Not treated (or medium binding) polystyrene ... binds biomolecules through passive interactions,• Is ... large molecules, such as antibodies, that ... interact with the surface,• Binding capacity ...
... tabs • Reusable, press-to-seal gasket and ... assembled and disassembled for hybridizing and imaging ... thickness with up to a 13 mm ... slide. Minimize specimen handling, eliminate evaporation and ...
...
Biology Products: