Navigation Links
Using computational biology for the annotation of proteins
Date:11/26/2012

they offer conclusions regarding the interpretation of those predictions, which may help explain the function of the cellular processes that were studied. "In particular," states Beatriz Garca, "the predictions obtained regarding two human proteins stand out (E3 SUMO-protein ligase y E3 ubiquitin-protein ligase DTX1); these were previously related to the controlled degradation of certain proteins, and we can now propose a new function related to the stabilization of telomeres and, therefore, their possible implication in cellular aging and the development of cancer, which will require experimental verification."

For this study, part of which was recently published in the journal PLOS ONE, the researcher has received the award for the best doctoral dissertation in her field (Experimental Sciences and Technology) from the Real Academia de Doctores de Espaa (Spanish Royal Academy of Doctors). The implications that this work holds for the scientific community are already being felt. In fact, the results of the first problem that the project analyzes have already been integrated into the predictions server EcID (E.coli Interaction Database) and they offer a reliability value for the predictions that improves the system's performance when finding functional associations among the proteins that appear in this database. Moreover, the second biological problem dealt with in the study opens a new area of research in Biocomputing, by extending already existing pathways. "The procedure it presents complements the only previously existing publication in the field, extending the pathways with many more proteins and exploring a greater surface of the network of interactions," comments the researcher. In addition, it could be applied to many more problems of functional annotation in Biology and other fields in which there is relevant information with multiple relationships.

In any case, much work remains to be done in the area of Biocomputation. "There are
'/>"/>

Contact: Ana Herrera
oic@uc3m.es
Carlos III University of Madrid
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Detective work using terahertz radiation
2. International team discovers likely basis of birth defect causing premature skull closure in infants
3. Taking the pulse of volcanoes using satellite images
4. UCSB scientists report new beginning in split-brain research, using new analytical tools
5. Primates brains make visual maps using triangular grids
6. UC Davis researchers develop new drug delivery system for bladder cancer using nanoparticles
7. Using planarian flatworms to understand organ regeneration
8. The slippery slope to slime: Overgrown algae causing coral reef declines
9. App lets you monitor lung health using only a smartphone
10. Deep-sea crabs seek food using ultraviolet vision
11. New study shows promise in using RNA nanotechnology to treat cancers and viral infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Using computational biology for the annotation of proteins
(Date:12/17/2014)...  HITLAB SM announced today its completion ... confirm its adherence to current U.S. Food and ... to conduct regulated smart device and smart phone ... safety and research quality. "HITLAB is ... delivery with innovative technology," said Laura Pugliese ...
(Date:12/17/2014)... Dec. 16, 2014  Automation is fundamentally transforming ... evident than at international borders. Over the past ... have allowed veteran travelers to self process through ... (APC) Kiosks at an increasing number of airports, ... According to Maxine Most , ...
(Date:12/11/2014)... 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition ... report to their offering. ... the adoption of multimodal biometric systems. Multimodal biometric ... individual for verification and identification purposes. This helps ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... Science Brief presents a roadmap for marine biodiversity science ... provides 95% of the habitable space on Earth and ... health of the oceans and their productive ecosystems which ... life is under significant threat from climate change and ...
... causing alarm among global public health authorities after it killed ... is now linked to two other cases of disease is ... found in bats, according to a genetic analysis to be ... the American Society for Microbiology, on November 20. Researchers studied ...
... including Carnegie Museum of Natural History scientist John ... Necrolestes patagonensis , whose name translates into grave ... This much-debated fossil mammal from South America has ... years. Scientific perseverance, a recent fossil discovery, and ...
Cached Biology News:Europe must not lose momentum in marine biodiversity research 2New coronavirus related to viruses from bats 2New coronavirus related to viruses from bats 3After 121 years, identification of 'grave robber' fossil solves a paleontological enigma 2After 121 years, identification of 'grave robber' fossil solves a paleontological enigma 3After 121 years, identification of 'grave robber' fossil solves a paleontological enigma 4After 121 years, identification of 'grave robber' fossil solves a paleontological enigma 5
(Date:12/17/2014)... BASKING RIDGE, N.J. (PRWEB) December 17, 2014 ... Ipsen (Euronext: IPN; ADR: IPSEY), ... 120 mg (referred to as Somatuline®) was approved ... for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) ... differentiated, locally advanced or metastatic disease to improve ...
(Date:12/17/2014)... Audacity, a leading California-based health and science ... Huntsworth Health Group, is proud to announce the addition ... role, Gonzales will serve as Senior Vice President of ... welcome a talent of Jamie’s caliber to the Audacity ... is a proven healthcare innovation leader and brand management ...
(Date:12/17/2014)... --  Synageva BioPharma Corp. (NASDAQ: GEVA ... disorders, announced today its presentation at the upcoming J.P. ... Francisco, CA. Sanj K. ... on Monday, January 12, 2015, at 9:00 a.m. PST ... and may be accessed from the "Webcasts & Presentations" ...
(Date:12/15/2014)... , Dec. 15, 2014  Origin Agritech Limited (NASDAQ ... a technology-focused supplier of crop seeds in China ... for its fiscal year 2014 ended September 30, 2014, before ... The Company will host a teleconference on January 8, 2015, ... time to discuss the results. To participate in ...
Breaking Biology Technology:Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 8Audacity Welcomes Healthcare Communications Expert Jamie Gonzales as Senior Vice President of Client Services 2Origin Agritech Limited to Announce Fiscal 2014 Annual Financial Results on January 8th, 2015 2Origin Agritech Limited to Announce Fiscal 2014 Annual Financial Results on January 8th, 2015 3
... YOKOHAMA, Japan, Aug. 27 MaxCyte,Inc. and ... the signing of an,exclusive license, development and ... system to support clinical studies and,commercialization of ... of the agreement, MaxCyte will provide the ...
... RESEARCH TRIANGLE PARK, N.C., Aug. 27 ... Pharmaceuticals, Inc., a,clinical-stage biopharmaceutical company specializing in ... private placement of C$26 million,(US$25 million) in ... investment by NovaQuest, the strategic partnering group,of ...
... Aug. 27 /Xinhua-PRNewswire-FirstCall/ -- China Technology,Development Group Corporation ... appointment of Charlene Hua as the Company,s new ... a board,resolution passed on the same date. This ... the Company. As Chief Financial Officer, Ms. ...
Cached Biology Technology:Medinet Licenses MaxCyte Cell Loading Technology for Cancer Immunotherapy in Japan 2Medinet Licenses MaxCyte Cell Loading Technology for Cancer Immunotherapy in Japan 3NovaQuest Advances 'Virtual Development' Model With Strategic Investment in TOPIGEN Pharmaceuticals 2China Technology Announces New Chief Financial Officer 2China Technology Announces New Chief Financial Officer 3