Navigation Links
Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins

Troy, N.Y. Researchers at Rensselaer Polytechnic Institute have developed a new way to seek out specific proteins, including dangerous proteins such as anthrax toxin, and render them harmless using nothing but light. The technique lends itself to the creation of new antibacterial and antimicrobial films to help curb the spread of germs, and also holds promise for new methods of seeking out and killing tumors in the human body.

Scientists have long been interested in wrapping proteins around carbon nanotubes, and the process is used for various applications in imaging, biosensing, and cellular delivery. But this new study at Rensselaer is the first to remotely control the activity of these conjugated nanotubes. Details of the project are outlined in the article Nanotube-Assisted Protein Deactivation in the December issue of Nature Nanotechnology.

A team of Rensselaer researchers led by Ravi S. Kane, professor of chemical and biological engineering, has worked for nearly a year to develop a means to remotely deactivate protein-wrapped carbon nanotubes by exposing them to invisible and near-infrared light. The group demonstrated this method by successfully deactivating anthrax toxin and other proteins.

By attaching peptides to carbon nanotubes, we gave them the ability to selectively recognize a protein of interest in this case anthrax toxin from a mixture of different proteins, Kane said. Then, by exposing the mixture to light, we could selectively deactivate this protein without disturbing the other proteins in the mixture.

By conjugating carbon nanotubes with different peptides, this process can be easily tailored to work on other harmful proteins, Kane said. Also, employing different wavelengths of light that can pass harmlessly through the human body, the remote control process will also be able to target and deactivate specific proteins or toxins in the human body. Shining light on the conjugated carbon nanotubews" imgurl="" timex="12/10/2007 10:12:07 AM" dirsub="(s creates free radicals called reactive ...)" id="1517" index="biology" dir="Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins" dir2="Using carbon nanotubes to seek and destroy anthrax toxin and other harmfu..." keywords1=",biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters" keywords="Using,carbon,nanotubes,to,seek,and,destroy,anthrax,toxin,and,other,harmful,proteins" description="s creates free radicals called reactive oxygen species. It was the pr...Kanes new method for selective nanotube-assisted protein deactivation ...Kanes team also developed a thin clear film made of carbon nanotubes ...The ability of these coatings to generate reactive oxygen species upon...Kane said he and his team will continue to hone this new technology an..." url=u&"/biology-news-1/Using-carbon-nanotubes-to-seek-and-destroy-anthrax-toxin-and-other-harmful-proteins-1517-2/" title="Using%20carbon%20nanotubes%20to%20seek%20and%20destroy%20anthrax%20toxin%20and%20other%20harmful%20proteins" %> Using carbon nanotubes to seek and destroy anthrax toxin and other harmfu... ( Troy N.Y. Researchers at Rensselaer...)

Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins

s creates free radicals, called reactive oxygen species. It was the presence of radicals, Kane said, that deactivated the proteins.

Kanes new method for selective nanotube-assisted protein deactivation could be used in defense, homeland security, and laboratory settings to destroy harmful toxins and pathogens. The method could also offer a new method for the targeted destruction of tumor cells. By conjugating carbon nanotubes with peptides engineered to seek out specific cancer cells, and then releasing those nanotubes into a patient, doctors may be able to use this remote protein deactivation technology as a powerful tool to prevent the spread of cancer.

Kanes team also developed a thin, clear film made of carbon nanotubes that employs this technology. This self-cleaning film may be fashioned into a coating that at the flip of a light switch could help prevent the spread of harmful bacteria, toxins, and microbes.

The ability of these coatings to generate reactive oxygen species upon exposure to light might allow these coatings to kill any bacteria that have attached to them, Kane said. You could use these transparent coatings on countertops, doorknobs, in hospitals or airplanes essentially any surface, inside or outside, that might be exposed to harmful contaminants.

Kane said he and his team will continue to hone this new technology and further explore its potential applications.


Contact: Michael Mullaney
Rensselaer Polytechnic Institute  

Related biology news :

1. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
2. Fever causing headaches for Aussie parents
3. Using evolution, UW team creates a template for many new therapeutic agents
4. Using green chemistry to deliver cutting-edge drugs
5. IGERT fellows to design biodevices using flexible electronics
6. Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
7. Computer program traces ancestry using anonymous DNA samples
8. Using nanotubes to detect and repair cracks in aircraft wings, other structures
9. Book on weeds and invasive plants discusses how to manage them using ecological approaches
10. Study shows housing development on the rise near national forests
11. Rare cancer-causing syndrome found, for the first time, in Singapore
Post Your Comments:
Related Image:
Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins
(Date:10/1/2015)... 2015  Biometrics includes diverse set of technologies ... such as fingerprints, eye retinas, facial patterns, voice ... technology has been constantly increasing in ... In addition to the most prominent popular method ... means of biometric authentication are rapidly gaining traction ...
(Date:9/29/2015)... News facts: ... energy , Minimized design shrinks PC footprint ... and embedded Fujitsu PalmSecure authentication enable enterprises to realize ... shows that good things come in small packages, with ... enterprise desktop and mobile portfolio. Featuring workplace design that ...
(Date:9/28/2015)... 28, 2015 The global ... USD 12.03 billion by 2020, growing at a CAGR ... as Backside Illumination (BSI) technique to improve picture quality ... period.      (Logo: , ... to reduce loss and, thus, reduce the noise interference ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... ... October 12, 2015 , ... LifeTrak , a leader ... LifeTrak Zoom, the world’s first amphibious fitness tracker that seeks to meet the needs ... and accurate heart rate monitoring both in water and on land, making ...
(Date:10/9/2015)... Oct. 9, 2015 On October 8, the ... Record her statement recognizing the third annual International Plasma ... is sponsored by the Plasma Protein Therapeutics Association ... to:   , Raise global awareness about plasma ... in saving and improving lives , Increase understanding ...
(Date:10/9/2015)... LEXINGTON, Mass. , Oct. 9, 2015  Pulmatrix, Inc., ... presentation at two upcoming investor conferences. th ... at 11:00 am PDT (2:00 pm EDT). --> ... 20, 2015 at 11:00 am PDT (2:00 pm EDT). ... James 2015 Small Cap Growth Stock Conference on Thursday, October ...
(Date:10/8/2015)... Fla. , Oct. 8, 2015   Intrexon ... synthetic biology, today announced the appointment of Joseph ... Environment Sector, succeeding Nir Nimrodi who continues ... Vaillancourt will direct Intrexon,s endeavors to generate sustainable, biologically ... America , where he held a variety of ...
Breaking Biology Technology: