Navigation Links
Use of Biomarkers in Clinical Trials for Drugs Outside of Oncology is Increasing
Date:11/12/2013

BURLINGTON, Mass., Nov. 12, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that while most of the biomarker-drug success stories are in oncology, biomarkers play a critical role in pharmaceutical development of chronic conditions, and their use in clinical trials of drugs outside of oncology is building. The Strategic Insights report entitled Driving Drug and Diagnostic R&D: The Influence of Biomarkers Beyond Oncology, finds that through biomarkers, upcoming chronic disease drugs will target new mechanisms of action, address niche subpopulations and fill the need for safer and more effective treatments. Biomarkers, when placed at the core of R&D programs, can reveal essential information about the drugs in development and/or the target populations.

According to the report, an analysis of ongoing clinical trials using biomarkers reveals a plethora of opportunities for drug R&D in a number of non-oncology therapy areas. Collectively, there are more clinical trials and deals over the last five years involving biomarkers for non-cancer indications than those focusing solely on cancer indications. For instance, all of AbbVie's trials using biomarkers are in non-cancer areas, as are more than half of all biomarker-focused trials sponsored by Merck, Roche, GlaxoSmithKline and Pfizer. While most active clinical trials involving biomarkers are in earlier phases, biomarkers in late-phase trials support label extension or evaluate long-term safety.

The report also explores how companies are capitalizing on the utility of biomarkers in the R&D programs in Alzheimer's disease, asthma, and type 2 diabetes.

"With the advances in biomarker research and in improved diagnostic imaging capabilities, the most notable impact
'/>"/>

SOURCE Decision Resources
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related biology news :

1. HUNT Biosciences and SomaLogic collaborate to validate protein biomarkers of cardiovascular risk
2. Trial seeks improved lung-cancer screening by combining imaging and biomarkers
3. Air pollution level changes in Beijing linked with biomarkers of cardiovascular disease
4. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
5. VEGF Inhibition: Therapy-Indicating and Prognostic Biomarkers, 2013
6. Spanish researchers design biomarkers for the detection of dengue and West Nile virus
7. NIH funds research to identify Parkinsons biomarkers
8. New AAN/ALS Association Clinical Fellow Will Pursue Immune Biomarkers
9. Epigenetic biomarkers may predict if a specific diet and exercise regimen will work
10. Novel biomarkers improve diagnosis in rheumatoid arthritis
11. Biomarkers Market: Epigenetic & MicroRNA Biomarkers Report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... SM announced today its completion of a Good ... current U.S. Food and Drug Administration (FDA) regulations. This ... smart phone application trials utilizing the highest principles for ... determined to improve global healthcare access, quality, and delivery ...
(Date:12/17/2014)... , Dec. 16, 2014  Automation is fundamentally transforming the ... at international borders. Over the past decade, ePassports, biometric ... to self process through border control via eGates and ... of airports, seaports, and land borders across the globe. ...
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition ... report to their offering. One major ... multimodal biometric systems. Multimodal biometric systems utilize more than ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... retirees, and other volunteers who are taking part in ... certain plants are blooming unusually early, perhaps as a ... the timing of flowers and foliage, amassing thousands of ... detailed picture of our changing climate. The project, ...
... release is available in Spanish . , ... generated artificial human skin by tissular engineering basing on agarose-fibrin ... development, maturation and functionality results were obtained. This pioneering finding ... use in many laboratory tests on biological tissues which, additionally, ...
... PROVIDENCE, R.I. [Brown University] Brown University professors Donald ... the American Academy of Arts and Sciences, the Cambridge, ... thinkers in scholarship and science, public affairs and business, ... James L. Manning professor of geological sciences, specializing in ...
Cached Biology News:'10 most wanted' plants inspected for clues to climate change 2'10 most wanted' plants inspected for clues to climate change 3Scientists create artificial human skin with biomechanical properties using tissue engineering 2Brown scientists elected to American Academy of Arts and Sciences 2
(Date:12/24/2014)... 23, 2014 SoundConnect’s ... introduce cutting edge communication technology, provide continued education ... This webinar series demonstrates online communication features and ... web conferencing’s most innovative and powerful tools. , ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 According to Ross ... Island Affiliate of ITRA Global, the national office market continues ... recovery. This is evidenced by the third quarter’s surprising ... market. Low energy costs have held inflation down and ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 Nashville Fertility Center ... treasurer for the American Society for Reproductive Medicine (ASRM), a ... reproductive medicine. In his new role as treasurer, Dr. ... will have a voice in furthering the mission of ASRM. ...
(Date:12/24/2014)... December 23, 2014 Pipette.com announces their ... can submit their #HolidayInTheLab pictures for a chance to win ... those struggling to think of a holiday gift for their ... provides the ideal holiday presents. The #HolidayInTheLab Contest encourages ...
Breaking Biology Technology:SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2
... PharmAthene, Inc. (NYSE Amex: PIP ), ... threats, today reported financial and operating results for the first ... first quarter of 2011 PharmAthene recognized revenue of $6.3 million ...  Revenues for the most recent quarter consisted of contract funding ...
... HCCS (Health Care Compliance Strategies, Inc.), the ... training and tracking solutions, today announced the release ... a web-based system for the management and real-time ... this comprehensive tool in response to tighter government ...
... ROCKVILLE, Md., May 11, 2011 Novavax, Inc. (Nasdaq: ... of the Year by the Tech Council of Maryland ... technology and biotechnology communities of Maryland.  Novavax was recognized ... the Maryland biotechnology community and for its presence and ...
Cached Biology Technology:PharmAthene Reports First Quarter 2011 Financial and Operating Results 2PharmAthene Reports First Quarter 2011 Financial and Operating Results 3PharmAthene Reports First Quarter 2011 Financial and Operating Results 4PharmAthene Reports First Quarter 2011 Financial and Operating Results 5PharmAthene Reports First Quarter 2011 Financial and Operating Results 6Conflict of Interest Disclosures Tool Updated 2Novavax Named Biotechnology Firm of the Year by Tech Council of Maryland 2
Ultra-sensitive, non-radioactive detection of rat Big Endothelin-1 (Big ET-1)...
Request Info...
Request Info...
Peptide Sequence: ovine COX-1 amino acids 272-282 (LMHYPRGIPPQ) To be used in conjunction with Cayman's COX-1 (ovine) polyclonal antiserum (Catalog No. 160108) to block protein-antibody complex f...
Biology Products: