Navigation Links
Urinary tract infections steal from hosts' defense arsenals
Date:7/8/2012

nfections who were treated at the University of Washington in Seattle.

"We found copper bound to yersiniabactin in nearly every patient whose bacteria made the molecule," Henderson says. "Yersiniabactin was often bound to copper more than it was to iron."

When researchers put E. coli in the same test tube with copper, the bacteria that made yersiniabactin were more likely to survive.

Copper's microbe-fighting properties were recognized long before scientists had described the microbes that cause infection. Ancient Greeks and Egyptians knew that treating wounds with copper improved the healing process.

Modern researchers have two explanations for copper's anti-microbial effects: the metal can stimulate production of other chemically reactive molecules that damage bacteria; and it is also directly toxic to the bacteria.

Henderson, who treats patients with urinary tract infections at Barnes-Jewish Hospital, is currently studying whether the presence or absence of yersiniabactin can help physicians assess an infection's chances of becoming more serious.

He and his colleagues are also looking at other disease-causing bacteria that make yersiniabactin to see if they use it in a fashion similar to the E. coli that cause urinary tract infections.


'/>"/>

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Beehive extract shows potential as prostate cancer treatment
2. Bigger gorillas better at attracting mates and raising young
3. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
4. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
5. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
6. Toward an alternative for antibiotics to fight bacterial infections?
7. Innate immune system protein provides a new target in war against bacterial infections
8. Vitamin D supplements may protect against viral infections during the winter
9. To drive infections, a hijacking virus mimics a cells signaling system
10. Stealthy microscopy method visualizes E. coli sub-cellular structure in 3-D
11. Stealing lifes building blocks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... WHEN: , Saturday to Wednesday, Oct. 18-22, 2014 ... 111 W. Harbor Drive, San Diego, CA 92101 ... sessions and other presentations of the latest research ... Opening plenary session featuring high-scoring abstracts on rare ... of various cancers, and treatment for sun sensitivity ...
(Date:8/21/2014)... standards process, will be available soon and will improve ... in the OnlineFirst version of Nutrition in Clinical ... the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.), ... misconnection that can be harmful and even fatal to ... medical devices, components, and accessories to deliver fluids or ...
(Date:8/21/2014)... replicated one of the crucial steps in photosynthesis, opening ... could manufacture hydrogen as a fuel. , "Water is ... prospect to use them to create hydrogen, and do ... the ARC Centre of Excellence for Translational Photosynthesis in ... potential as a zero-carbon replacement for petroleum products, and ...
Breaking Biology News(10 mins):American Society of Human Genetics 2014 Annual Meeting 2New feeding tube connectors will improve patient safety 2Water and sunlight the formula for sustainable fuel 2
... secret to longevity may lie in an enzyme with the ... by maintaining the function of the thymus throughout life, according ... than a typical mouse. The study, led by Abbe ... of Pittsburgh School of Medicine, and immunologist at Children,s Hospital ...
... in Montana of the first trace fossil of a dinosaur ... more dinosaur burrows this time on the other side ... published this month in Cretaceous Research , suggests that ... different hemispheres, and spanned millions of years during the Cretaceous ...
... mathematician at the Department of Energy,s Pacific Northwest National ... Award for Scientists and Engineers. The award honors his ... energy needs: cleaning up buried nuclear or toxic contaminants ... Announced by the White House, the PECASE is ...
Cached Biology News:Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging 2Down Under dinosaur burrow discovery provides climate change clues 2Down Under dinosaur burrow discovery provides climate change clues 3PNNL scientist garners early career presidential award 2
(Date:8/21/2014)... LYNBROOK, N.Y. , Aug. 21, 2014 /PRNewswire/ ... a biopharmaceutical company developing first in class collagenase-based ... histolyticum or CCH) in the U.S. and XIAPEX ... statistically significant results from a randomized, double-blind Phase ... of cellulite, or edematous fibrosclerotic panniculopathy. The results ...
(Date:8/21/2014)... Texas (PRWEB) August 21, 2014 ... Seaweed Fertilizer Industry” is a professional and ... market. The report provides basic Seaweed Fertilizer ... and industry chain structure as well as ... market analysis, including domestic market as well ...
(Date:8/21/2014)... August 21, 2014 The College of ... private college in the Mid-Hudson Region to be designated ... begin accepting applications from qualified “high-technology” businesses that align ... very pleased to have been selected for the START-UP ... transformative initiative to stimulate economic development in New York ...
(Date:8/21/2014)... HONG KONG , Aug. 21, 2014  China Cord ... today announced its plan to release financial results for ... August 28, 2014, after market close in the US.  ... call at 8:00 a.m. ET on Friday, August 29, ... brief overview of the Company,s recent developments, followed by ...
Breaking Biology Technology:BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2
... , , , , Which of the following statements best describes your , ... , , ... , , , ... <a , href="http://www.roche-applied-science.com/pcr/product_find_PCR01a.htm">I , ...
... , for one-step RT-PCR amplification of up to , ... Cat. No. 1 855 476100 reactions , Cat. No. 1 ... Description , , , Components of the Titan ... reaction. The system , includes the following components: , ...
... , , for amplification of GC-rich targets (up to , ... , , , , , , ... Unique enzyme blend of Taq DNA Polymerase and , Pwo DNA Polymerase[a ... The GC-RICH PCR System also includes: , ...
Cached Biology Technology:Find the optimal product for your PCR application 2Titan One Tube RT-PCR System / Kit 2GC-RICH PCR System 2
... Molecular Probes is pleased to ... for the ultrasensitive detection of primary ... at Indiana University, the ATTO-TAG reagents ... o-phthaldialdehyde (OPA), naphthalene-2,3-dicarboxaldehyde (NDA) and anthracene-2,3-dicarboxaldehyde, ...
Troponin I Immunogen: Full length native protein (purified) (Human). Storage: -20 C, Avoid Freeze/Thaw Cycles...
Corticoliberin...
...
Biology Products: