Navigation Links
Unveiling the structure of microcrystals
Date:10/4/2007

Microcrystals take the form of tiny grains resembling powder, which is extremely difficult to study. For the first time, researchers from the European Synchrotron Radiation Facility (ESRF) and the Centre National de Recherche Scientifique used X-ray diffraction at the synchrotron to determine the structure of microcrystal grains of one cubic micrometre. They gained a factor of a thousand on the size of the analysable samples, opening up new research possibilities to chemists, physicists and biologists.

The properties of a crystal are determined by the arrangement of its atom in space, its crystalline structure. Scientists use X-ray or neutron diffraction to study crystalline structure when the size of the crystal is more than 10 cubic micrometres. Below this limit, the solid material is considered a powder. Scientists can apply powder diffraction to analyse such a material but this technique is not easy to exploit. Moreover, powder diffraction can only be used for materials with grain sizes of less than three millionths of a cubic micrometre. Due to these limitations, a determination of the structure of new synthetic solids in powder form is not always possible because the crystals are too small.

The teams from the ESRF and the Institute Lavoisier (CNRS/Universit de Versailles Saint-Quentin) have used new set-up permitting X-ray diffraction on crystals of a size of one cubic micrometre, a volume a thousand times smaller than that ever attainable before. This new set-up consists of a focussing system for the ESRF beam, coupled with a goniometer, an instrument to position the sample with maximum precision.

The researchers studied the structure of an organic-inorganic hybrid compound (a microporous aluminium carboxylate), which could be used for gas absorption or to encapsulate various organic molecules. This study confirms that the new set-up allows pushing back the limits in crystal dimension accessible to X-ray diffraction.

It is a revolution: what was considered a powder in the past has become a crystal today. Researchers can now bring forward samples left in their cupboards because the sizes had previously prevented their study. Now they will be able to elucidate the structures of these samples, with potentially great scientific advances on the horizon, explains Thierry Loiseau, from the Institut Lavoisier.


'/>"/>

Contact: Montserrat Capellas
capellas@esrf.fr
33-476-882-663
European Synchrotron Radiation Facility
Source:Eurekalert

Related biology news :

1. Man and mouse share genome structures
2. The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
3. Scientists solve structure of key protein in innate immune response
4. Vascular structure and function improve with diet and exercise
5. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
6. SuperLigands - a database of ligand structures derived from the Protein Data Bank
7. Structure-building cell signals also may influence learning and memory
8. PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
9. DNA constraints control structure of attached macromolecules
10. Scripps research scientists solve structure of a critical innate immune system protein
11. Major advance made on DNA structure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2016)... 2016 Securus Technologies, a leading provider ... public safety, investigation, corrections and monitoring announced that ... has secured the final acceptance by all three ... Access Systems (MAS) installed. Furthermore, Securus will have ... installed by October, 2016. MAS distinguishes between legitimate ...
(Date:6/9/2016)... 2016 Paris Police Prefecture ... security solution to ensure the safety of people and operations ... the major tournament Teleste, an international technology group ... announced today that its video security solution will be utilised ... up public safety across the country. The system roll-out is ...
(Date:6/2/2016)... , June 2, 2016   The Weather Company , ... Watson Ads, an industry-first capability in which consumers will be ... able to ask questions via voice or text and receive ... Marketers have long sought an advertising ... that can be personal, relevant and valuable; and can scale ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... , ... Parallel 6 , the leading software as a service (SaaS) ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication between ... Using the CONSULT module, patients and physicians can schedule a face to face virtual ...
(Date:6/24/2016)... 2016  Regular discussions on a range of subjects including ... two entities said Poloz. Speaking at a lecture ... , he pointed to the country,s inflation target, which is ... "In certain areas there ... common economic goals, why not sit down and address strategy ...
(Date:6/23/2016)... WI (PRWEB) , ... June 23, 2016 , ... ... supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, into ... for over 35 years, is proud to add Target to its list of ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm Sciences, Inc. ... test has received AOAC Research Institute approval 061601. , “This is another AOAC-RI ... stated Bob Salter, Vice President of Regulatory and Industrial Affairs. “The Peel Plate ...
Breaking Biology Technology: