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Unraveling biological networks
Date:3/5/2012

nd clusters them hierarchically to reveal the presence of recurring motifs in the network. The team has applied the algorithm to a network of protein-protein interaction (PPI) for the well-studied bacterium Escherichia coli and the yeast Saccharomyces cerevisiae.

"Our experimental results show that the algorithm can efficiently discover motifs, which are consistent with current biology knowledge," the team says. Importantly, however, the approach has also revealed several novel motifs previously unrecognised. "Our algorithm can detect several consensus motifs with a given size, which may help biologists go further into cellular process," the team adds.


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Contact: Lin Gao
lgao@mail.xidian.edu.cn
Inderscience Publishers
Source:Eurekalert

Page: 1 2

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