Navigation Links
Unmasking DNA
Date:9/4/2007

DNA is one of the most popular building blocks of nanotechnology and is commonly used to construct ordered nanoscale structures with controlled architectures. For the most part, DNA is looked upon as a promising building block for fabricating microelectronic circuits from the bottom up. Now a team of researchers at Young propose the marriage of DNA self-assembly with standard microfabrication and lithography tools to form features such as nanochannels, nanowires, and nanoscale trenches. This discovery may open up new avenues for nanofabrication at dimensions not accessible by conventional optical lithography.

Adam Woolley and Hctor Becerril have developed a method to use DNA molecules as templates to define patterns on substrates. The researchers deposit metal films over DNA molecules aligned on a substrate. The DNA molecules essentially act as nanostencils to define sub-10-nm-sized patterns on the substrate. The researchers call this process "DNA shadow nanolithography" because the metal film is deposited at an angle and the shadow cast by the DNA molecules defines the dimensions of the features on the substrate.

Anisotropic etching of the patterned surfaces using reactive gas plasmas, a commonly used fabrication tool in the semiconductor industry, yields high-aspect-ratio trenches on the substrate. The trenches can be sealed at the top to form continuous enclosed nanochannels. Alternatively, the trenches can be chemically functionalized and used as templates for the deposition of metal nanowires such as those of nickel, copper, or silver. The templated trenches and nanowires have lateral dimensions less than 30 nm and can be tailored to be less than 10 nm. The exact dimensions of the trenches can be varied by tuning the angle of deposition and the thickness of the deposited film.

The researchers believe that it should be possible to transfer complex patterns onto substrates using surface-aligned DNA molecules. "One remarkable aspect of this technology is that it utilizes the patterning ability of DNA without requiring the nucleic acid to remain in the final construct", said Woolley, adding that the nanostructures fabricated by DNA shadow nanolithography may find use as nanofluidic channels and chemical sensors.
'/>"/>

Contact: Adam T. Woolley
wadam@byu.edu
801-422-1701
John Wiley & Sons, Inc.
Source:Eurekalert

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2016)... OTTAWA, Ontario , PROVO ... 2016 Newborn Screening Ontario (NSO), which operates ... for molecular testing, and Tute Genomics and ... process management technology respectively, today announced the launch of ... new next-generation sequencing (NGS) testing panel. ...
(Date:3/17/2016)... LONDON , March 17, 2016 ... market intelligence, forecasts the global biometrics market will ... an impressive 118% increase from 2015. Consumer electronics, ... with embedded fingerprint sensors anticipated to reach two ... Dimitrios Pavlakis , Research Analyst ...
(Date:3/14/2016)... NXTD ) ("NXT-ID" or the "Company"), ... the airing of a new series of commercials on Time ... 21 st .  The commercials will air on Bloomberg TV, ... the Street show. --> NXTD ) ("NXT-ID" or ... market, announces the airing of a new series of commercials ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... ... April 28, 2016 , ... Morris Midwest ( http://www.morrismidwest.com ... regional manufacturers at its Maple Grove, Minnesota technical center, May 11-12. The ... Trumpf. Almost 20 leading suppliers of tooling, accessories, software and other related ...
(Date:4/27/2016)... , April 27, 2016 ... (CSE: NSK) (OTCPink: NSKQB) ( Frankfurt ... an ihre Pressemitteilung vom 13. August 2015 die ... ihre Finanzen um zusätzliche 200.000.000 Einheiten auf 400.000.000 ... Dollar zu bringen. Davon wurden 157.900.000 Einheiten mit ...
(Date:4/27/2016)... ... April 27, 2016 , ... A compact PET scanner called ... MRI (Magnetic Resonance Imaging) in existing third-party MRI systems. PET and MRI are ... animal subjects. Simultaneous PET/MRI imaging offers a solution to many challenges that face ...
(Date:4/26/2016)... ... April 27, 2016 , ... Cameron Cushman ... an associate in the firm’s Intellectual Property practice group. , Clients turn to ... applications. He has an electrical engineering and computer engineering background, and experience in ...
Breaking Biology Technology: