Navigation Links
Unmasking DNA
Date:9/4/2007

DNA is one of the most popular building blocks of nanotechnology and is commonly used to construct ordered nanoscale structures with controlled architectures. For the most part, DNA is looked upon as a promising building block for fabricating microelectronic circuits from the bottom up. Now a team of researchers at Young propose the marriage of DNA self-assembly with standard microfabrication and lithography tools to form features such as nanochannels, nanowires, and nanoscale trenches. This discovery may open up new avenues for nanofabrication at dimensions not accessible by conventional optical lithography.

Adam Woolley and Hctor Becerril have developed a method to use DNA molecules as templates to define patterns on substrates. The researchers deposit metal films over DNA molecules aligned on a substrate. The DNA molecules essentially act as nanostencils to define sub-10-nm-sized patterns on the substrate. The researchers call this process "DNA shadow nanolithography" because the metal film is deposited at an angle and the shadow cast by the DNA molecules defines the dimensions of the features on the substrate.

Anisotropic etching of the patterned surfaces using reactive gas plasmas, a commonly used fabrication tool in the semiconductor industry, yields high-aspect-ratio trenches on the substrate. The trenches can be sealed at the top to form continuous enclosed nanochannels. Alternatively, the trenches can be chemically functionalized and used as templates for the deposition of metal nanowires such as those of nickel, copper, or silver. The templated trenches and nanowires have lateral dimensions less than 30 nm and can be tailored to be less than 10 nm. The exact dimensions of the trenches can be varied by tuning the angle of deposition and the thickness of the deposited film.

The researchers believe that it should be possible to transfer complex patterns onto substrates using surface-aligned DNA molecules. "One remarkable aspect of this technology is that it utilizes the patterning ability of DNA without requiring the nucleic acid to remain in the final construct", said Woolley, adding that the nanostructures fabricated by DNA shadow nanolithography may find use as nanofluidic channels and chemical sensors.
'/>"/>

Contact: Adam T. Woolley
wadam@byu.edu
801-422-1701
John Wiley & Sons, Inc.
Source:Eurekalert

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/15/2016)... --> --> ... Research "Digital Door Lock Systems Market - Global Industry Analysis, ... global digital door lock systems market in terms of revenue ... forecast to grow at a CAGR of 31.8% during the ... enterprises (MSMEs) across the world and high industrial activity driving ...
(Date:3/11/2016)... March 11, 2016 http://www.apimages.com ) - ... Picture is available at AP Images ( http://www.apimages.com ) - ... be used to produce the new refugee identity cards. DERMALOG will ... at CeBIT in Hanover next week.   ... will be used to produce the new refugee identity cards. DERMALOG ...
(Date:3/9/2016)... March 9, 2016 This BCC Research report ... of the RNA Sequencing (RNA Seq) market for the ... instruments, tools and reagents, data analysis, and services. ... of the RNA-Sequencing market such as RNA-Sequencing tools and ... main factors affecting each segment and forecast their market ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... , ... May 25, 2016 , ... ... Fitzmaurice recently became double board-certified in surgery and surgery of the hand by ... Fitzmaurice is no stranger to going above and beyond in his pursuit of ...
(Date:5/25/2016)... , ... May 25, 2016 , ... ... Food and Drug Administration (FDA) has granted the company’s orphan drug designation request ... second orphan drug designation granted by the FDA. , Spinocerebellar ataxia is ...
(Date:5/23/2016)... ... May 23, 2016 , ... The need for blood donations in South Texas and across the ... Texas Blood & Tissue Center, blood donations are on the decline. In fact, donations across ... down 21 percent in South Texas in the last four years alone. , There is ...
(Date:5/23/2016)... ... May 23, 2016 , ... RoviSys, a ... based in Aurora, Ohio, has broken ground on a new building in Holly ... Park area, this new location solidifies a commitment to business in the region. ...
Breaking Biology Technology: