Navigation Links
University of Wisconsin chemists find new compounds to curb staph infection
Date:5/23/2013

erium uses to regulate quorum sensing. The new agents devised by Blackwell and her group work on the four subtypes of staph, all of which use different quorum sensing signals and are found in different infection types.

"We had not worked much in this area because the (signaling molecules) are somewhat challenging to synthesize," explains Blackwell. "We now have developed methods to make these molecules and analogs much more efficiently, which helped fuel this new study."

For now, the compounds devised by the Wisconsin team will have their greatest impact in the lab as research probes to further study the role of quorum sensing in Staphylococcus aureus. In addition, the gritty details of how these synthetic agents work in the cell need to be determined in order to optimize their potential use in both the lab and clinic. Such studies are ongoing.

"The impact of these new peptides could be significant because staph is an important and increasingly scary pathogen. There is plenty of scope," notes Blackwell.


'/>"/>

Contact: Helen Blackwell
blackwell@chem.wisc.edu
608-262-1503
University of Wisconsin-Madison
Source:Eurekalert

Page: 1 2

Related biology news :

1. University of Maryland Medical Center launches genetic-testing program for cardiac patients
2. University of Maryland School of Medicine researchers find potential novel treatment for influenza
3. University of Houston engineering professor awarded grant to study melanoma treatment
4. Saint Louis University, University of Toronto biologists help decode turtle genome
5. Wayne State University startup, Advaita, to participate in new Michigan I-Corps program
6. Indiana University associate professor earns APSs Henry Pickering Bowditch Award
7. University of Southern California scientists reveal natural process that blocks viruses
8. University of Houston engineering researchers theories to be tested in space
9. University of Tennessee professors research shows Gulf of Mexico resilient after spill
10. Mercyhurst Universitys new DNA sequencer to accelerate scientific research in region
11. Student named universitys first Lawrence scholar, researching at national laboratory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... SM announced today its completion of a Good ... current U.S. Food and Drug Administration (FDA) regulations. This ... smart phone application trials utilizing the highest principles for ... determined to improve global healthcare access, quality, and delivery ...
(Date:12/11/2014)... Markets , http://photos.prnewswire.com/prnh/20130307/600769 ... addition of the "Biometrics Market in the APAC ... One major trend emerging in this market is advances ... important to upgrade biometric solutions to the latest standard ...
(Date:12/10/2014)... 9, 2014  Valencell, a leader in performance biometric data ... demand from its licensees for highly accurate, clinically validated ... solely coming from fitness and health sectors, but first ... wearable is only as useful as the biometric data ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... feeds on a native tree from the western Pacific island of ... are out of reach for its only local natural enemy," said ... ecologist Thomas Marler to study the relationship between the native cycad ... alien insect pest called cycad aulacaspis scale (CAS). The pest arrived ...
... comparative analysis to date of bacterial communities inhabiting the ... into why some individuals become colonized with pathogens while ... in mBio the online open-access journal published by the ... are important sites of pathogen colonization, yet the microbiota ...
... that increasing certain proteins in the blood vessels of ... The study provides new avenues for research that may ... demonstrates that cytochrome P450 plays an important role in ... enormous public health concern," said Darryl Zeldin, M.D., acting ...
Cached Biology News:Cycad pest uses small size to hide from predators 2Study examines, compares bacteria in the nose and throat 2NIH-supported study finds novel pathway may open doors for new blood pressure treatments 2
(Date:1/22/2015)... (PRWEB) January 22, 2015 Pipette.com has ... to their comprehensive portfolio of Eppendorf products. , ... to purchase a Centrifuge 5424/5424 R and receive the ... either Eppendorf Research plus or Eppendorf Reference 2 ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Selexis SA, ... mammalian Research Cell Banks (RCBs) used for drug discovery ... Cell Banks will include Next-Generation Sequencing (NGS) ... architecture de-risks biologic manufacturing by ensuring the integrity of ...
(Date:1/22/2015)... , Jan. 22. 2015  Varian Medical Systems (NYSE: ... been honored for its commitment to sustainability with inclusion on ... is the highest ranked healthcare equipment company among the Corporate ... the World Economic Forum at Davos, Switzerland ...
(Date:12/24/2014)...  United Therapeutics Corporation (NASDAQ: UTHR ) announced ... has submitted a pre-market approval application to the U.S. ... Medtronic,s SynchroMed ® II implantable drug infusion system ... Therapeutics, Remodulin ® (treprostinil) Injection delivered intravenously to ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Varian Honored Among World's 100 Most Sustainable Corporations 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4
... , The Isopure Buccal Cell DNA Kit is a simple, ... genomic DNA for downstream applications , such as ... collection formats using SPRI magnetic bead technology , ... , Buccal Kit effectively and consistently delivers high ...
... Agencourts RNAClean kit provides a simple, flexible and ... products generated in common enzymatic , RT and ... , gene expression analysis experiments and is easily ... eliminates the need for vacuum filtration or , ...
... Although the <A , ... Labeling Kits were developed for labeling siRNA, they can , ... can be used for this application. See "<A , ... Introduced dsRNA in Cells " for experimintal data using dsRNA , ...
Cached Biology Technology:Isopure - Buccal cell DNA isolation 2RNAClean - RNA & cDNA in vitro Reaction Purification 2Fluorescently Labeling Long dsRNA with the Silencer siRNA Labeling Kit 2Fluorescently Labeling Long dsRNA with the Silencer siRNA Labeling Kit 3Fluorescently Labeling Long dsRNA with the Silencer siRNA Labeling Kit 4
EDG-1 Western blot control Source: Cell Lysate Application: Western Blotting Control...
...
Kit containing positive control DNA all parts of the HIV-1 genome, HIV-1 negative control DNA, Primers SK38, SK39, SK19...
Request Info...
Biology Products: