Navigation Links
University of Toronto scientists map entire yeast genome
Date:11/26/2007

TORONTO, ON. University of Toronto scientists have devised a tool to help understand and predict the state of a cell by successfully mapping all 70,000 nucleosomes in yeast. Nucleosomes wrap DNA before it is transformed into proteins and are critical indicators and regulators of a cells state.

Led by Corey Nislow, a U of T Assistant Professor with the Banting and Best Department of Medical Research and Department of Molecular Genetics, the team created a complete, three-dimensional map of the yeast genome. This information was fed into a computer to build a software program that can predict where nucleosomes should be. The program worked remarkably well, and its accuracy will only improve with more data.

When control is lost, cells make inappropriate proteins or divide inappropriately, which is what happens in diseases like cancer, says Nislow, whose team worked closely with U of T Professor Timothy Hughes on the project. Knowing where nucleosomes are is the first step in identifying what is going on in a cell and what the cell plans to do next, so this initial research could have big implications down the road for early detection of certain diseases.

Scientists can tell by the presence of nucleosomes which genes are actively being converted into protein, and this information can function as an important first clue to disease detection.


'/>"/>

Contact: April Kemick
april.kemick@utoronto.ca
416-978-5949
University of Toronto
Source:Eurekalert

0

GOOD

Page: 1

Related biology news :

1. A study by the MUHC and McGill University opens a new door to understanding cancer
2. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
3. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
4. Bioengineers at University of Pennsylvania devise nanoscale system to measure cellular forces
5. Binghamton University researchers investigate evolving malaria resistance
6. Antioxidant to retard wrinkles discovered by Hebrew University researcher
7. Society for General Microbiology 161st Meeting, University of Edinburgh
8. Boston University biomedical engineers find chink in bacterias armor
9. KAUST and American University in Cairo to collaborate on research and academic development
10. UNH becomes first university in nation to use landfill gas as primary energy source
11. University of Minnesota study refutes belief that black men have more aggressive prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... new report from the Institute of Medicine says schools ... least 60 minutes of vigorous or moderate intensity activity ... of American youth meet current evidence-based guidelines of at ... activity daily, according to the report, which was released ... nearly half of their waking hours, the committee recommends ...
(Date:5/23/2013)... Frontiers, one of the world,s largest and fastest ... new journal, Frontiers in Bioengineering and Biotechnology ... all specialties, Frontiers in Bioengineering and Biotechnology ... diverse and emerging bioengineering and biotechnology research to ... in Bioengineering and Biotechnology will provide an ...
(Date:5/22/2013)... May 22, 2013 U.S. Forest Service scientists are ... with funding from the TKF Foundation, will examine how ... and individuals recover from tragedy. , The TKF Foundation ... six projects selected for grant funding. In addition to ... spaces in recovery and resiliency, the 3-year, $585,000 grant ...
Breaking Biology News(10 mins):Schools should provide students with daily physical activity, IOM recommends 2Frontiers launches new open-access journal in Bioengineering and Biotechnology 2'Landscapes of Resilience' to study how people use nature as a source of recovery 2
... New York, NY -- The Damon Runyon Cancer ... exceptional early career researchers and innovative cancer research, ... November 2009 Fellowship Award Committee review. The ... postdoctoral scientists conducting basic and translational cancer research ...
... This release is available in Spanish . ... programme to collect and remove unnecessary cellular components. Autophagy ... components, which, if not disintegrated and recycled, threaten cell ... (IRB Barcelona) led by Antonio Zorzano, head of the ...
... Reducing salt in the American diet by as little ... nearly 100,000 heart attacks and 92,000 deaths each year, according ... with the benefits from reductions in smoking and could save ... researchers add. A team from the University of ...
Cached Biology News:Damon Runyon Cancer Research Foundation awards prestigious fellowships to 11 top young scientists 2Damon Runyon Cancer Research Foundation awards prestigious fellowships to 11 top young scientists 3Researchers identify a new gene involved in autophagy, the cellular recycling program 2Even small dietary reductions in salt could mean fewer heart attacks, strokes and deaths 2Even small dietary reductions in salt could mean fewer heart attacks, strokes and deaths 3
(Date:5/24/2013)... TEL AVIV, Israel , May 24, 2013 ... NSPR), a leader in embolic protection stents, announced that ... Executive Officer, and Craig Shore , the ... LLC One-on-One Investor Conference on Thursday May 30, 2013 at ... WI. The format of the conference ...
(Date:5/24/2013)... Vestiage, Inc. (stock symbol "VEST") a publicly ... and development, sales and marketing of premium branded ... that it is awarding exclusive Vestiage territories in ... Skin Illuminating Facial Care. Qualified applicants can request ... email to info(at)vestiageinc(dot)com and putting RELUMA in the ...
(Date:5/23/2013)... , May 23, 2013  BioScrip, Inc. (NASDAQ: ... present at the Jefferies 2013 Global Healthcare Conference to ... New York. Richard Smith ... Hai Tran , Chief Financial Officer, will present ... Daylight Time.   About BioScrip BioScrip, ...
(Date:5/23/2013)... Ind. , May 23, 2013  Rahal Letterman ... in human cord blood stem cell banking and therapeutics, ... of the No. 16 Acorn Stairlifts Indy car driven ... for the remainder of the IZOD IndyCar 2013 season. ... (RLL) will work to support awareness of umbilical cord ...
Breaking Biology Technology:InspireMD To Participate In Benchmark Investor Conference On May 30th 2InspireMD To Participate In Benchmark Investor Conference On May 30th 3InspireMD To Participate In Benchmark Investor Conference On May 30th 4Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 2Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 3Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 4Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 5StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3
... to Wisconsin, is working with Madison Environmental Group on a ... online extortionists are holding personal files for ransom, and a ... , ,Original air date: Saturday, May 28, 2005 , , ... Read more about the Culver's deal ...
... good at tolerating unexpected difference. The boxes tend to get ... power curve or an unanticipated condition in the data stream. ... course, is our ability to manage our own intractability, assuming ... , ,We've all heard about people who begin to ...
... market failed to reach double-digit growth in 2004 for the ... focused on concerns over drug safety, pricing and competition from ... ,Let's take a look at how the market did. This ... market research firm: , ,If the overall growth ...
Cached Biology Technology:Machine like me 2Machine like me 3Though pharma growth slides, blockbusters reach new record 2Though pharma growth slides, blockbusters reach new record 3
Form: Ready to use Applications: Immunohistology-frozen, Immunohistology-paraffin, Western Blot, ELISA...
... 200RT rotary tables offer precision motorized rotation ... compatible with Parkers linear positioners and its ... multi-axis configurations., , Preloaded, precision worm ... Dual race preloaded angular contact support bearing ...
Wnt-1 (G-19)...
TGF-beta 1,-2,-3 MAb (Clone 1D11)...
Biology Products: