Navigation Links
University of Tennessee Space Institute researchers make clinical trials a virtual reality
Date:8/30/2012

Clinical trials can be time-consuming, expensive and intrusive, but they are also necessary. Researchers at the University of Tennessee Space Institute in Tullahoma have developed an invention that makes clinical trials more efficient by moving them into the virtual world.

Called "digital Eye Bank," the computer software eye modeling program includes data from people's eyes for researchers to use when testing their inventions. Developed by Ying-Ling Chen, research assistant professor of physics and Jim Lewis, professor emeritus in physics, Eye Bank can take data from eyes of patients' and build it into models from the commercial optics program to be used for researchers' virtual clinical trials.

A video about the invention can be viewed by visiting http://bit.ly/Osuxia.

"The idea of Eye Bank is to use existing clinical data and build in realistic and personalized eye models stored in a ready-to-use tool kit like a group of volunteers," said Chen. "Then we can call on any specific eye to test a newly designed optical instrument on the computer and see what kind of performance the design gets. This testing can be done repeatedly without hurting real human subjects."

Currently 35 eyes with various demographics and conditions from Wang Vision Center in Nashville are included in Eye Bank. This variety, combined with the researchers' control of conditions, may allow results of testers' finished product to be more refined before advancing to the real clinical trial phase, which is administered by a third-party.

"Being able to mathematically and computationally describe the visual response of normal and abnormal eyes and sub-groups of the population allows for optimal results of designing the technology," said Chen.

In most clinical trials used today, the types and conditions of eyes that are studied are not as varied as desired because it is difficult and expensive to find the diversity and range of subjects. The result is an uncertainty in the performance of new instruments to detect and diagnose a range of unusual eye conditions. In the virtual world, users can manipulate the eye, such as opening it partially or rotating the pupil. They can also give it certain conditions, such as growing a cataract or developing a tear duct issue. This allows users to see how well their instrument measures in response to such conditions.

This characteristic can be especially useful in assisting surgical planning by predicting outcomes of visual performance.

"For instance, we can predict how one person's eye can react to LASIK surgery and simulate the day and night vision after the procedure," said Chen. "Today, it is also not well known on how the long-term outcome of new interventions would be. But in the virtual world, we could induce cataract and dry eye and other aging conditions to predict the possible complicated outcomes and problems."

Eye Bank could also be helpful in medical education, as most students are not trained on diseased eyes.

Although currently used for optical research, the researchers see broad applications for their technology.

The research is currently undergoing testing funded by the National Institutes of Health.


'/>"/>

Contact: Whitney Heins
wheins@utk.edu
865-974-5460
University of Tennessee at Knoxville
Source:Eurekalert  

Related biology news :

1. University of Leicester takes delivery of unique eye imaging equipment
2. University of Tennessee Team receives NSF support to study toxic water in China
3. George Washington University Computational Biology Director solves 200-year-old oceanic mystery
4. University of Minnesota engineering researchers discover new non-invasive method for diagnosing epilepsy
5. Prestigious Royal Society of Tropical Medicine and Hygiene journals join Oxford University Press
6. MDA supports Duchenne muscular dystrophy research by University of Nevada School of Medicine
7. University of Minnesota receives $13.1 million in DOE funding for 2 new nationwide centers
8. University of Toronto wins third place at the Gates Foundations Reinvent the Toilet Challenge
9. NIH backs Rice University study of delay in gene transcription networks
10. New forensic institute at the University of Leicester will help police forces solve unusual crimes
11. University of Tennessee professor releases weight management product
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
University of Tennessee Space Institute researchers make clinical trials a virtual reality
(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
(Date:6/2/2016)... The Weather Company , an IBM Business (NYSE: IBM ... which consumers will be able to interact with IBM Watson ... or text and receive relevant information about the product or ... long sought an advertising solution that can create a one-to-one ... valuable; and can scale across millions of interactions and touchpoints. ...
(Date:6/1/2016)... 2016 Favorable Government Initiatives Coupled ... Criminal Identification to Boost Global Biometrics System Market Through ... Research report, " Global Biometrics Market By Type, ... Opportunities, 2011 - 2021", the global biometrics market is ... account of growing security concerns across various end use ...
Breaking Biology News(10 mins):
(Date:6/23/2016)...  The Biodesign Challenge (BDC), a university competition that ... living systems and biotechnology, announced its winning teams at ... New York City . The teams, ... at MoMA,s Celeste Bartos Theater during the daylong summit. ... curator of architecture and design, and Suzanne Lee ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... launch of the Supplyframe Design Lab . Located in Pasadena, Calif., the ... future of how hardware projects are designed, built and brought to market. , ...
(Date:6/23/2016)... ... June 23, 2016 , ... In a new case report published ... how a patient who developed lymphedema after being treated for breast cancer benefitted from ... the paradigm for dealing with this debilitating, frequent side effect of cancer treatment. ...
(Date:6/23/2016)... 2016  Blueprint Bio, a company dedicated to identifying, ... community, has closed its Series A funding round, according ... "We have received a commitment from Forentis Fund ... to meet our current goals," stated Matthew Nunez ... to complete validation on the current projects in our ...
Breaking Biology Technology: