Navigation Links
University of Saskatchewan and Canadian Synchrotron researchers shed light on esophageal disease
Date:6/7/2009

SASKATOON, SASKATCHEWAN Canadian Light Source (CLS) staff scientist Luca Quaroni and Dr. Alan Casson, Head of the Department of Surgery at the University of Saskatchewan (U of S) used the synchrotron's infrared microscope to identify tissue afflicted with a condition known as Barrett's Esophagus from chemical fingerprints associated with the disease, which can lead to esophageal cancer. The finding is published in the June, 2009 issue of the Royal Society of Chemistry journal, The Analyst.

"The advantage to using microscopes with synchrotron light is that it allows us to identify chemical biomarkers inside specific cells," says Dr. Quaroni, who conducted the synchrotron analysis. "Often the differences between healthy and malignant tissue can be quite small, but the differences seen here were quite striking. This is a good proof of concept for developing a traceable technique that matches what can be seen at the macroscopic scale using microscopic samples."

The team analyzed preserved samples of healthy and diseased tissue that Dr. Casson had collected during esophageal biopsies. Using a technique known as Fourier Transform Infrared Microscopy, Quaroni and Casson identified specific chemicals known as biomarkers - within the individual cells that make up the tissue. It was found that increased concentrations of particular biomarkers such as glycoproteins were associated with the Barrett's tissue.

Barrett's Esophagus (BE) occurs when the cells that normally line the esophagus the tube that connects our throat to our stomach are replaced by cells that resemble those that line the intestine. While BE only affects approximately one percent of Americans, the number of people diagnosed with the condition is on the rise, with the increasing incidence of chronic heartburn (gastro-esophageal reflux disease or GERD) considered a risk factor for developing BE. The disease in turn can lead to an aggressive form of cancer known as esopha
'/>"/>

Contact: Matthew Dalzell
matt.dalzell@lightsource.ca
306-657-3739
Canadian Light Source, Inc.
Source:Eurekalert  

Page: 1 2

Related biology news :

1. A study by the MUHC and McGill University opens a new door to understanding cancer
2. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
3. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
4. Bioengineers at University of Pennsylvania devise nanoscale system to measure cellular forces
5. Binghamton University researchers investigate evolving malaria resistance
6. Antioxidant to retard wrinkles discovered by Hebrew University researcher
7. Society for General Microbiology 161st Meeting, University of Edinburgh
8. Boston University biomedical engineers find chink in bacterias armor
9. KAUST and American University in Cairo to collaborate on research and academic development
10. UNH becomes first university in nation to use landfill gas as primary energy source
11. University of Minnesota study refutes belief that black men have more aggressive prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
University of Saskatchewan and Canadian Synchrotron researchers shed light on esophageal disease
(Date:5/5/2015)... , May 5, 2015, NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market, reminds investors and ... Technology Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, ... 2015. The three-day conference is organized into ... speaking in is themed Global Fraud: Where is the ...
(Date:4/27/2015)... Apr. 27, 2015 Profile Solutions, Inc. (OTC: ... security systems is pleased to announce that Dr ... consultant and member of its scientific advisory board. ... as a thought leader in technology-enhanced learning models. He ... and has published studies and books focused on online ...
(Date:4/20/2015)... 2015 The announcement comes as ... Records Management (GRM), Ireland,s foremost records ... Having built up an impressive track record of clients within ... within the records management sector in Dubai ... GCC staffbase and employ a further eight staff members at ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... Aug. 17--Researchers are able to achieve extremely high-resolution microscopy ... microscopy. This cutting-edge imaging system has pushed the performance ... to image features that are even smaller than the ... able to achieve this extreme vision by using a ...
... Switzerland have investigated the remarkable distance that microorganisms may ... their potential to colonise new lands and also potentially ... Moores University (LJMU), Swiss Federal Institute for Forest, Snow ... de Lausanne (EPFL) the University of Neuchtel published their ...
... have used tools of paleontology to gain new insights into ... during the evolution of these compounds nature doesn,t settle for ... giving pointers that will help in the search for potent ... the study of the evolution of the characteristic swirl shapes ...
Cached Biology News:Life on the wind: Study reveals how microbes travel the Earth 2Nature reaches for the high-hanging fruit 2
(Date:5/28/2015)... 28, 2015 Clinerion, an ... Switzerland, and the Alliance for Clinical Research ... non-profit organization operating in the public interest ... to enhance quality, safety, integrity and operational ... research, are pleased to announce their partnership ...
(Date:5/27/2015)... , May 27, 2015 RXi Pharmaceuticals ... focused on discovering and developing innovative therapies primarily ... that it has commenced a public offering of ... shares of its common stock and overallotment purchase ... The shares of common stock, warrants and overallotment ...
(Date:5/27/2015)... , May 26, 2015 Research and ... the "Global Breast Cancer Monoclonal Antibodies Market ... Globally, Roche seems to dominate the breast ... Its block buster molecule, Herceptin has been able ... was found that breast cancer cells become recalcitrant ...
(Date:5/27/2015)... 2015 Expanding in a big way ... Avalon Biomed Inc. recently inked a deal with ... Co. Ltd. , the largest endodontic distributor in Japan. ... market for Avalon Biomed, which manufactures Grey MTA Plus® ... dental cements that have won renown from dentists around ...
Breaking Biology Technology:Clinerion and ACRES Partner on Patient Recruitment and Risk-Based Quality Management 2Clinerion and ACRES Partner on Patient Recruitment and Risk-Based Quality Management 3RXi Pharmaceuticals Announces Proposed Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces Proposed Public Offering of Common Stock and Warrants 3Global Breast Cancer Monoclonal Antibodies Market Outlook 2020 2Global Breast Cancer Monoclonal Antibodies Market Outlook 2020 3Dental Manufacturer Avalon Biomed Inks Major Deal with Japanese Distributor 2Dental Manufacturer Avalon Biomed Inks Major Deal with Japanese Distributor 3
... 25 EntreMed, Inc.,(Nasdaq: ENMD ) a ... cancer and inflammatory diseases, today,announced that James S. ... Corporate overview at the BioCentury Future Leaders in ... Millennium Broadway Hotel &,Conference Center, March 27, 2008. ...
... March 25 Senesco,Technologies, Inc. (the "Company") (Amex: ... from the American Stock Exchange ("AMEX") stating that ... in the AMEX,s,letters dated June 15, 2007 and ... review of publicly available information pertaining to the ...
... and misleading information, SOUTH SAN FRANCISCO, ... Board: VXGN.OB), (Logo: ... On March 19th, MedCap Management & Research, ... release entitled "MedCap Urges Vote Against Proposed,VaxGen ...
Cached Biology Technology:EntreMed to Present at BioCentury Future Leaders in the Biotech Industry Conference 2Senesco Technologies Regains Compliance With Amex's Continued Listing Requirements 2Senesco Technologies Regains Compliance With Amex's Continued Listing Requirements 3VaxGen Issues Rebuttal to MedCap Letter 2VaxGen Issues Rebuttal to MedCap Letter 3VaxGen Issues Rebuttal to MedCap Letter 4VaxGen Issues Rebuttal to MedCap Letter 5VaxGen Issues Rebuttal to MedCap Letter 6VaxGen Issues Rebuttal to MedCap Letter 7VaxGen Issues Rebuttal to MedCap Letter 8VaxGen Issues Rebuttal to MedCap Letter 9VaxGen Issues Rebuttal to MedCap Letter 10VaxGen Issues Rebuttal to MedCap Letter 11
Rabbit polyclonal to SERHL ( Abpromise for all tested applications). entrezGeneID: 94009 SwissProtID: Q9H4I8...
Sheep polyclonal to Staphylococcus DNase ( Abpromise for all tested applications). Antigen: Full length native protein (purified)....
Allophycocyanin (APC) anti-human CD193 (CCR3, CKR3) 25 tests...
Goat polyclonal to PPP2R5D Immunogen: Peptide with sequence KRAEEFLTASQEAL, from C Terminus of the protein sequence according to NP_006236...
Biology Products: